Results 21 to 30 of about 69,571 (187)
AgronomyPlant height (PH) is a vital agronomic trait that significantly affects cotton yield and facilitates mechanized harvesting. Gaining insights into the genetic regulatory mechanisms governing plant height is fundamental to advancing cotton breeding.
Qian Huang +6 more
doaj +2 more sources
Weighted gene co-expression network analysis of hub genes in lung adenocarcinoma [PDF]
Evolutionary Bioinformatics, 2021 Lung adenocarcinoma (LUAD) is a tumor with high incidence. This study aimed to identify the central genes of LUAD. LUAD were analyzed by weighted gene co-expression network (WGCNA), and differentially expressed genes (DEGs) were identified. Samples were obtained from The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) databases and ...
Xuan Luo +4 more
openaire +3 more sources
Identification of key gene modules and genes in colorectal cancer by co-expression analysis weighted gene co-expression network analysis [PDF]
Bioscience Reports, 2020 Abstract Colorectal cancer (CRC) has been one of the most common malignancies worldwide, which tends to get worse for the growth and aging of the population and westernized lifestyle. However, there is no effective treatment due to the complexity of its etiology. Hence, the pathogenic mechanisms remain to be clearly defined.
Peng Wang +7 more
openaire +2 more sources
Identification of Key Genes and Pathways Associated With Endometriosis by Weighted Gene Co-Expression Network Analysis [PDF]
SSRN Electronic Journal, 2021 Background: Endometriosis is a common gynecological disorder with high rates of infertility and pelvic pain. However, its pathogenesis and diagnostic biomarkers remain unclear. This study aimed to elucidate potential hub genes and key pathways associated with endometriosis in ectopic endometrium (EC) and eutopic endometrium (EU).
Wu, Jingni +2 more
openaire +2 more sources
Gene co-expression network analysis of Trypanosoma brucei in tsetse fly vector
Parasites & Vectors, 2021 Background Trypanosoma brucei species are motile protozoan parasites that are cyclically transmitted by tsetse fly (genus Glossina) causing human sleeping sickness and nagana in livestock in sub-Saharan Africa. African trypanosomes display digenetic life
Kennedy W. Mwangi +2 more
doaj +1 more source
BMC Cardiovascular Disorders, 2021 Background Aneurysm is a severe and fatal disease. This study aims to comprehensively identify the highly conservative co-expression modules and hub genes in the abdominal aortic aneurysm (AAA), thoracic aortic aneurysm (TAA) and intracranial aneurysm ...
Siwei Bi +4 more
doaj +1 more source
Distance correlation application to gene co-expression network analysis
BMC Bioinformatics, 2022 Background To construct gene co-expression networks, it is necessary to evaluate the correlation between different gene expression profiles. However, commonly used correlation metrics, including both linear (such as Pearson’s correlation) and monotonic ...
Jie Hou +7 more
doaj +1 more source
Rice Science, 2022 Zinc (Zn) malnutrition is a major public health issue. Genetic biofortification of Zn in rice grain can alleviate global Zn malnutrition. Therefore, elucidating the genetic mechanisms regulating Zn deprivation response in rice is essential to identify ...
Blaise Pascal Muvunyi +4 more
doaj +1 more source
Weighted gene co-expression network analysis identifies functional modules related to bovine respiratory disease. [PDF]
PLoS OneBovine respiratory disease (BRD) is a multifactorial disease of dairy and beef cattle that involves complex interactions with the host immune system. In the current study, a comprehensive meta-analysis was performed using a P-value combination approach ...
Ghahramani N, Hashemi A, Panahi B.
europepmc +2 more sources
Hub genes of stroke identified by weighted gene co-expression network analysis [PDF]
, 2019 Abstract Background Microarray-based gene expression profiling has been widely used in biomedical research. Weighted gene co-expression network analysis (WGCNA) can link microarray data directly to clinical traits and to identify rules for predicting pathological stage and prognosis of disease, it has been found useful in many biological ...
Junhong Li +6 more
openaire +2 more sources