Results 31 to 40 of about 69,571 (187)

Edge-weighting of gene expression graphs [PDF]

, 2009
In recent years, considerable research efforts have been directed to micro-array technologies and their role in providing simultaneous information on expression profiles for thousands of genes.
Kerr, Gráinne, Crane, Martin, DIMITRI PERRIN, HEATHER J. RUSKIN, Ruskin, Heather J., Perrin, Dimitri, MARTIN CRANE, GRAINNE KERR, Ruskin, Heather J   +8 more
core   +1 more source

Weighted Gene Co-expression Network Analysis of Glioblastoma Gene Expression Microarray Data

, 2023
Glioblastoma is a highly aggressive and lethal form of brain cancer characterized by its complex molecular landscape. Understanding the underlying gene expression patterns and their relationships is essential for unraveling the mechanisms driving this ...
G.Madhusudhan, Pandurangan, Sujatha, T.Geetharathan   +2 more
core   +1 more source

Identification of PDK4 as Hub Gene for Diabetic Nephropathy Using Co-Expression Network Analysis

Kidney & Blood Pressure Research, 2023
Introduction: Diabetic nephropathy (DN) is related to type 1 and type 2 diabetes. They are the leading cause of end-stage renal disease, but the underling specific pathogenesis of DN is not yet clear. Our study was conducted to explore how DN changed the
Yuanyuan Han, Liangzi Jin, Liangzhi Wang, LAN WEI, CHAO TU   +4 more
doaj   +1 more source

Identification of Hub Genes and Potential ceRNA Networks of Diabetic Nephropathy by Weighted Gene Co-Expression Network Analysis [PDF]

Frontiers in Genetics, 2021
Diabetic nephropathy (DN) is one of the most common microvascular complications in diabetic patients, and is the main cause of end-stage renal disease. The exact molecular mechanism of DN is not fully understood. The aim of this study was to identify novel biomarkers and mechanisms for DN disease progression by weighted gene co-expression network ...
Guoqing Li, Jun Zhang, Dechen Liu, Qiong Wei, Hui Wang, Yingqi Lv, Zheng Ye, Gaifang Liu, Ling Li, Ling Li   +9 more
openaire   +3 more sources

Assessment of Weighted Gene Co-Expression Network Analysis to Explore Key Pathways and Novel Biomarkers in Muscular Dystrophy

Pharmacogenomics and Personalized Medicine, 2021
Xiaoxue Xu,1 Yuehan Hao,1 Jiao Wu,2 Jing Zhao,1 Shuang Xiong3 1Department of Neurology, The First Hospital of China Medical University, Shenyang, People’s Republic of China; 2Department of Neurology, The People’s Hospital of Liaoning Province,
Xu X, Hao Y, Wu J, Zhao J, Xiong S
doaj  

Construction and Analysis of a Diagnostic Model Based on Differential Expression Genes in Patients With Major Depressive Disorder

Frontiers in Psychiatry, 2021
Background: Major depressive disorder (MDD) is a common and severe psychiatric disorder with a heavy burden on the individual and society. However, the prevalence varies significantly owing to the lack of auxiliary diagnostic biomarkers.
Qing Long, Rui Wang, Maoyang Feng, Xinling Zhao, Yilin Liu, Xiao Ma, Lei Yu, Shujun Li, Zeyi Guo, Yun Zhu, Zhaowei Teng, Yong Zeng   +11 more
doaj   +1 more source

Comprehensive analysis of diabetic nephropathy expression profile based on weighted gene co-expression network analysis algorithm

BMC Nephrology, 2021
Background Diabetic nephropathy (DN) is the major complication of diabetes mellitus, and leading cause of end-stage renal disease. The underlying molecular mechanism of DN is not yet completely clear.
Alieh Gholaminejad, Mohammad Fathalipour, Amir Roointan   +2 more
doaj   +1 more source

Identification of the hub genes in gastric cancer through weighted gene co-expression network analysis

PeerJ, 2021
Background Gastric cancer is one of the most lethal tumors and is characterized by poor prognosis and lack of effective diagnostic or therapeutic biomarkers. The aim of this study was to find hub genes serving as biomarkers in gastric cancer diagnosis and therapy.
Li, Chunyang, Yu, Haopeng, Sun, Yajing, Zeng, Xiaoxi, Zhang, Wei   +4 more
openaire   +3 more sources

Using Weighted Gene Co-Expression Network Analysis to Identify Increased MND1 Expression as a Predictor of Poor Breast Cancer Survival

International Journal of General Medicine, 2022
Zhaokang Bao,1,* Jiale Cheng,1,* Jiahao Zhu,2,* Shengjun Ji,3 Ke Gu,2 Yutian Zhao,2 Shiyou Yu,1 You Meng1 1Department of Oncology Surgery, The Affiliated Suzhou Hospital of Nanjing Medical University, Gusu School, Nanjing Medical University ...
Bao Z, Cheng J, Zhu J, Ji S, Gu K, Zhao Y, Yu S, Meng Y   +7 more
doaj  

Modular network inference between miRNA–mRNA expression profiles using weighted co-expression network analysis

Journal of Integrative Bioinformatics, 2021
Connecting transcriptional and post-transcriptional regulatory networks solves an important puzzle in the elucidation of gene regulatory mechanisms. To decipher the complexity of these connections, we build co-expression network modules for mRNA as well ...
Wani Nisar, Barh Debmalya, Raza Khalid
doaj   +1 more source