Results 51 to 60 of about 212,786 (294)

Treatment-associated mRNA co-expression changes in monocytes of patients with posttraumatic stress disorder

Frontiers in Psychiatry, 2023
PTSD is a prevalent mental disorder that results from exposure to extreme and stressful life events and comes at high costs for both the individual and society.
Robert Kumsta, Robert Kumsta, Johannes C. S. Zang, Elisabeth M. Hummel, Svenja Müller, Dirk A. Moser, Stephan Herpertz, Henrik Kessler, Henrik Kessler   +8 more
doaj   +1 more source

Identification of Key Modules and Hub Genes Involved in Regulating the Color of Chicken Breast Meat Using WGCNA

Animals, 2023
Meat color is one of the most important economic traits in chickens. However, the gene network and regulatory mechanisms contributing to meat color traits in chickens remain largely unknown.
Xing Guo, Hong Zhang, Hao Wang, Xin-Xin He, Jiang-Xian Wang, Wei Wei, Meng Liu, Jin-Mei Xu, Ya-Nan Liu, Run-Shen Jiang   +9 more
doaj   +1 more source

Weighted Gene Co-Expression Network Analysis Combined with Machine Learning Validation to Identify Key Modules and Hub Genes Associated with SARS-CoV-2 Infection

Journal of Clinical Medicine, 2021
The coronavirus disease-2019 (COVID-19) pandemic has caused an enormous loss of lives. Various clinical trials of vaccines and drugs are being conducted worldwide; nevertheless, as of today, no effective drug exists for COVID-19.
H. Karami, Afshin Derakhshani, Mohammad Ghasemigol, M. Fereidouni, E. Miri-Moghaddam, B. Baradaran, Neda Jalili Tabrizi, S. Najafi, A. Solimando, L. Marsh, N. Silvestris, S. De Summa, A. Paradiso, V. Racanelli, H. Safarpour   +14 more
semanticscholar   +1 more source

CD36 identified by weighted gene co-expression network analysis as a hub candidate gene in lupus nephritis [PDF]

PeerJ, 2019
Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), which often progresses to end-stage renal disease (ESRD) and ultimately leads to death.
Huiying Yang, Hua Li
doaj   +2 more sources

Weighted gene co-expression network analysis of the salt-responsive transcriptomes reveals novel hub genes in green halophytic microalgae Dunaliella salina

Scientific Reports, 2021
Despite responses to salinity stress in Dunaliella salina, a unicellular halotolerant green alga, being subject to extensive study, but the underlying molecular mechanism remains unknown.
B. Panahi, M. Hejazi
semanticscholar   +1 more source

Weighted Gene Co-expression Network Analysis of Key Biomarkers Associated With Bronchopulmonary Dysplasia

Frontiers in Genetics, 2020
Bronchopulmonary dysplasia (BPD) is a complex disorder resulting from interactions between genes and the environment. The accurate molecular etiology of BPD remains largely unclear.
Yao Cai, Fei Ma, LiuHong Qu, LiuHong Qu, Binqing Liu, Hui Xiong, Yanmei Ma, Sitao Li, Hu Hao   +8 more
doaj   +1 more source

Transcriptome profiling of developing leaf and shoot apices to reveal the molecular mechanism and co-expression genes responsible for the wheat heading date

BMC Genomics, 2021
Background Wheat is one of the most widely planted crops worldwide. The heading date is important for wheat environmental adaptability, as it not only controls flowering time but also determines the yield component in terms of grain number per spike ...
Yuxin Yang, Xueying Zhang, Lifen Wu, Lichao Zhang, Guoxiang Liu, Chuan Xia, Xu Liu, Xiuying Kong   +7 more
doaj   +1 more source

Identifying disease progression biomarkers in metabolic associated steatotic liver disease (MASLD) through weighted gene co-expression network analysis and machine learning

Journal of Translational Medicine
Metabolic Associated Steatotic Liver Disease (MASLD), encompassing conditions simple liver steatosis (MAFL) and metabolic associated steatohepatitis (MASH), is the most prevalent chronic liver disease. Currently, the management of MASLD is impeded by the
Weiliang Zhang, Weirong Lu, Yaqi Jiao, Tian-Hao Li, Hai-Ning Wang, Chun-Hua Wan   +5 more
semanticscholar   +1 more source

Weighted Gene Co-Expression Network Analysis Identifies Critical Genes in the Development of Heart Failure After Acute Myocardial Infarction

Frontiers in Genetics, 2019
Background: The development of heart failure (HF) remains a common complication following an acute myocardial infarction (AMI), and is associated with substantial adverse outcomes.
Xiao-Wei Niu, Jing-Jing Zhang, Lanlan Zhang, Yangfang Hou, Shuangshuang Pu, A. Chu, M. Bai, Zheng Zhang   +7 more
semanticscholar   +1 more source

Screening of potential biomarkers in peripheral blood of patients with depression based on weighted gene co-expression network analysis and machine learning algorithms

Frontiers in Psychiatry, 2022
Background The prevalence of depression has been increasing worldwide in recent years, posing a heavy burden on patients and society. However, the diagnostic and therapeutic tools available for this disease are inadequate.
Zhe Wang, Zhe Meng, Che Chen
semanticscholar   +1 more source