Results 61 to 70 of about 69,571 (187)

Immune infiltration landscape and immune-marker molecular typing of pulmonary fibrosis with pulmonary hypertension

BMC Pulmonary Medicine, 2021
Background Pulmonary arterial hypertension (PH) secondary to pulmonary fibrosis (PF) is one of the most common complications in PF patients, it causes severe disease and usually have a poor prognosis.
Haomin Cai, Hongcheng Liu
doaj   +1 more source

Novel prognostic genes and subclasses of acute myeloid leukemia revealed by survival analysis of gene expression data

BMC Medical Genomics, 2021
Background Acute myeloid leukemia (AML) is biologically heterogeneous diseases with adverse prognosis. This study was conducted to find prognostic biomarkers that could effectively classify AML patients and provide guidance for treatment decision making.
Yanli Lai, Guifang OuYang, Lixia Sheng, Yanli Zhang, Binbin Lai, Miao Zhou   +5 more
doaj   +1 more source

Identification of Prognostic Genes in Leiomyosarcoma by Gene Co-Expression Network Analysis

Frontiers in Genetics, 2020
Background/AimsLeiomyosarcoma (LMS) is a tumor derived from malignant mesenchymal tissue associated with poor prognosis. Determining potential prognostic markers for LMS can provide clues for early diagnosis, recurrence, and treatment.Methods RNA ...
Jun Yang, Cuili Li, Jiaying Zhou, Xiaoquan Liu, Shaohua Wang   +4 more
doaj   +1 more source

Weighted gene co-expression network analysis revealed T cell differentiation associated with the age-related phenotypes in COVID-19 patients

BMC Medical Genomics, 2023
The risk of severe condition caused by Corona Virus Disease 2019 (COVID-19) increases with age. However, the underlying mechanisms have not been clearly understood. The dataset GSE157103 was used to perform weighted gene co-expression network analysis on
Yao Lin, Yueqi Li, Hubin Chen, Jun Meng, Jingyi Li, Jiemei Chu, Ruili Zheng, Hailong Wang, Peijiang Pan, Jinming Su, Junjun Jiang, Li Ye, Hao Liang, Sanqi An   +13 more
doaj   +1 more source

Mean Expression of the X-Chromosome is Associated with Neuronal Density. [PDF]

, 2012
peer reviewedBackground: Neurodegenerative diseases are characterized by key features such as loss of neurons, astrocytosis, and microglial activation/proliferation. These changes cause differences in the density of cell types between control and disease
Pascal F. Durrenberger, James Thomas Swingland, Durrenberger, Pascal F, Swingland, James T., Reynolds, Richard, DEPREZ, Manuel, Pombo, A., Deprez, M, Roncaroli, F, Durrenberger, P.F., David T Dexter, Richard eReynolds, Dexter, DT, Turkheimer, Federico E; id_orcid, Turkheimer, Federico E., James T. Swingland, Ana Pombo, Federico Roncaroli, Turkheimer, FE, Swingland, J.T., Durrenberger, PF, David T. Dexter, Pombo, Ana, Dexter, David T, Durrenberger, Pascal F., Reynolds, R, Turkheimer, F.E., Manuel eDeprez, Swingland, James T, Federico E. Turkheimer, Dexter, D.T., Roncaroli, Federico, Federico eRoncaroli, Richard Reynolds, Reynolds, R., Turkheimer, Federico E, Manuel Deprez, Pombo, A, Pascal F Durrenberger, Ana ePombo, Dexter, David T., Deprez, M., Roncaroli, F., Swingland, JT   +43 more
core   +1 more source

Identification of prognostic biomarkers for papillary thyroid carcinoma by a weighted gene co‐expression network analysis

Cancer Medicine, 2022
Aim Whole transcriptome analysis was conducted to identify differentially expressed RNAs and regulatory networks associated with papillary thyroid carcinoma (PTC). Methods A weighted gene co‐expression network analysis based on high‐throughput sequencing
Kexin Meng, Xiaotian Hu, Guowan Zheng, Chenhong Qian, Ying Xin, Haiwei Guo, Ru He, Minghua Ge, Jiajie Xu   +8 more
doaj   +1 more source

Gene Correlation Network Analysis to Identify Biomarkers of Peri-Implantitis

Medicina, 2022
Background and Objectives: The histopathological and clinical conditions for transforming peri-implant mucositis into peri-implantitis (PI) are not fully clarified. We aim to uncover molecular mechanisms and new potential biomarkers of PI.
Binghuan Sun, Wei Zhang, Xin Song, Xin Wu   +3 more
doaj   +1 more source

Predicting glioblastoma prognosis networks using weighted gene co-expression network analysis on TCGA data

, 2012
Background Using gene co-expression analysis, researchers were able to predict clusters of genes with consistent functions that are relevant to cancer development and prognosis.
Huang Kun, Zhang, Cun-Quan, Zhang Cun-Quan, Xiang Yang, Xiang, Yang, Huang, Kun   +5 more
core   +1 more source

Investigation of hub gene associated with the infection of Staphylococcus aureus via weighted gene co-expression network analysis

BMC Microbiology, 2021
Introduction Staphylococcus aureus is a gram-positive bacterium that causes serious infection. With the increasing resistance of bacteria to current antibiotics, it is necessary to learn more about the molecular mechanism and cellular pathways involved ...
Jia-xin Li, Xun-jie Cao, Yuan-yi Huang, Ya-ping Li, Zi-yuan Yu, Min Lin, Qiu-ying Li, Ji-chun Chen, Xu-guang Guo   +8 more
doaj   +1 more source

Up-Regulation of TRIM32 Associated With the Poor Prognosis of Acute Myeloid Leukemia by Integrated Bioinformatics Analysis With External Validation

Frontiers in Oncology, 2022
BackgroundAcute myeloid leukemia (AML) is a malignant and molecularly heterogeneous disease. It is essential to clarify the molecular mechanisms of AML and develop targeted treatment strategies to improve patient prognosis.MethodsAML mRNA expression data
Xiaoyan Xu, Xiaoyan Xu, Xiaoyan Xu, Xiaoyan Xu, Jiaqian Qi, Jiaqian Qi, Jiaqian Qi, Jiaqian Qi, Jingyi Yang, Jingyi Yang, Jingyi Yang, Jingyi Yang, Tingting Pan, Tingting Pan, Tingting Pan, Tingting Pan, Haohao Han, Haohao Han, Haohao Han, Haohao Han, Meng Yang, Meng Yang, Meng Yang, Meng Yang, Yue Han, Yue Han, Yue Han, Yue Han   +27 more
doaj   +1 more source