Results 61 to 70 of about 212,786 (294)

The Role of Vitamin D in the Transcriptional Program of Human Pregnancy. [PDF]

PLoS ONE, 2016
Patterns of gene expression of human pregnancy are poorly understood. In a trial of vitamin D supplementation in pregnant women, peripheral blood transcriptomes were measured longitudinally on 30 women and used to characterize gene co-expression networks.
Amal Al-Garawi, Vincent J Carey, Divya Chhabra, Hooman Mirzakhani, Jarrett Morrow, Jessica Lasky-Su, Weiliang Qiu, Nancy Laranjo, Augusto A Litonjua, Scott T Weiss   +9 more
doaj   +1 more source

Integrative analysis identifies oxidative stress biomarkers in non-alcoholic fatty liver disease via machine learning and weighted gene co-expression network analysis

Frontiers in Immunology
Background Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease globally, with the potential to progress to non-alcoholic steatohepatitis (NASH), cirrhosis, and even hepatocellular carcinoma.
Hai-Ning Wang, Wei Cheng, Ping Hu, Tao Ling, Chao Hu, Yong-Zhen Chen, Ya-Nan Zheng, Jun-Qi Wang, Ting Zhao, Qiang You   +9 more
semanticscholar   +1 more source

Identification of Hub Genes and Key Pathways Associated With Bipolar Disorder Based on Weighted Gene Co-expression Network Analysis

Frontiers in Physiology, 2019
Bipolar disorder (BD) is a complex mental disorder with high mortality and disability rates worldwide; however, research on its pathogenesis and diagnostic methods remains limited.
Yang Liu, Hui-Yun Gu, Jie Zhu, Yu-Ming Niu, Chao Zhang, Guang-Ling Guo   +5 more
semanticscholar   +1 more source

WGCNA: an R package for weighted correlation network analysis

BMC Bioinformatics, 2008
Background Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method for describing the correlation patterns among genes across microarray ...
Horvath Steve, Langfelder Peter
doaj   +1 more source

Exploiting systems biology to investigate the gene modules and drugs in ovarian cancer: A hypothesis based on the weighted gene co-expression network analysis.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021
BACKGROUND Ovarian cancer (OC) is one of the worrisome gynecological cancers worldwide. Given its considerable mortality rate, it is necessary to investigate its oncogenesis. METHODS In this study, we used systems biology approaches to describe the key
Samira Nomiri, H. Karami, B. Baradaran, Darya Javadrashid, Afshin Derakhshani, Niloufar Sadat Nourbakhsh, Mahdi Abdoli Shadbad, Antonio Giovanni Solimando, Neda Jalili Tabrizi, O. Brunetti, S. Nasseri, V. Racanelli, H. Safarpour, N. Silvestris   +13 more
semanticscholar   +1 more source

Construction of a prediction model for metastasis in gastric cancer based on the weighted gene co-expression network analysis

Zhongguo aizheng zazhi, 2021
Background and purpose: This study aimed to screen out the bio-markers related to the occurrence and metastasis of gastric cancer. The weighted gene co-expression network analysis (WGCNA) was performed to analyze the gene chips containing metastatic ...
龚　超, 陈　魁, 章德昆, 谢径峰, 吴芳华, 黄玉钿, 薛玉钦, 王力群   +7 more
doaj  

Exploration and validation of key genes associated with early lymph node metastasis in thyroid carcinoma using weighted gene co-expression network analysis and machine learning

Frontiers in Endocrinology, 2023
Background Thyroid carcinoma (THCA), the most common endocrine neoplasm, typically exhibits an indolent behavior. However, in some instances, lymph node metastasis (LNM) may occur in the early stages, with the underlying mechanisms not yet fully ...
Yan-Yan Liu, Zheng-Ming Yin, Yao Wang, Hao-Hao Chen   +3 more
semanticscholar   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Using weighted gene co-expression network analysis to identify key genes related to preeclampsia. [PDF]

Front Immunol
IntroductionThe pathogenesis of preeclampsia remains unclear, highlighting the need for the creation of dependable biomarkers. This study aimed to pinpoint genetic risk factors linked to preeclampsia through the utilization of weighted gene co-expression network analysis (WGCNA).MethodsA gene expression profile dataset from the placentas of patients ...
Shen X, Zeng Z, Xie L, Yue X, Wang Z.
europepmc   +4 more sources

Weighted gene co-expression network analysis reveals key genes involved in pancreatic ductal adenocarcinoma development

Cellular Oncology, 2016
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Up till now, the patient’s prognosis remains poor which, among others, is due to the paucity of reliable early diagnostic biomarkers.
M. Giulietti, G. Occhipinti, G. Principato, F. Piva   +3 more
semanticscholar   +1 more source