Results 21 to 30 of about 499,911 (300)
Reviews in Endocrine & Metabolic Disorders, 2023 Adipose tissue, including white adipose tissue (WAT), brown adipose tissue (BAT), and beige adipose tissue, is vital in modulating whole-body energy metabolism. While WAT primarily stores energy, BAT dissipates energy as heat for thermoregulation.
Zeinab Ghesmati +5 more
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White Adipose Tissue Dysfunction: Pathophysiology and Emergent Measurements
Nutrients, 2023 White adipose tissue (AT) dysfunction plays an important role in the development of cardiometabolic alterations associated with obesity. AT dysfunction is characterized by the loss of the expansion capacity of the AT, an increment in adipocyte ...
Natalia Santillana +3 more
semanticscholar +1 more source
Nature Immunology, 2021 White adipose tissue (WAT) is an essential regulator of energy storage and systemic metabolic homeostasis. Regulatory networks consisting of immune and structural cells are necessary to maintain WAT metabolism, which can become impaired during obesity in
Andrew D Hildreth +5 more
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Exercise-Mediated Browning of White Adipose Tissue: Its Significance, Mechanism and Effectiveness
International Journal of Molecular Sciences, 2021 As a metabolic organ, adipose tissue plays an important role in regulating metabolism. In adults, most adipose tissue is white adipose tissue (WAT), and excessive expansion of WAT will lead to obesity.
Wang-Jing Mu +3 more
semanticscholar +1 more source
Dynamic changes in the transcriptome of tRNA-derived small RNAs related with fat metabolism
Scientific Data, 2023 The prevalence of obesity and overweight is steadily rising, posing a significant global challenge for humanity. The fundamental cause of obesity and overweight lies in the abnormal accumulation of adipose tissue.
Tianci Liao +6 more
doaj +1 more source
Nature Communications, 2021 Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network.
Anna Whitehead +19 more
semanticscholar +1 more source
Mitochondrial regulation and white adipose tissue homeostasis.
Trends in Cell Biology, 2021 The important role of mitochondria in the regulation of white adipose tissue (WAT) remodeling and energy balance is increasingly appreciated. The remarkable heterogeneity of the adipose tissue stroma provides a cellular basis to enable adipose tissue plasticity in response to various metabolic stimuli.
Qingzhang Zhu, Yu A. An, P. Scherer
semanticscholar +3 more sources
Obesity, white adipose tissue and cancer. [PDF]
FEBS JWhite adipose tissue (WAT) is crucial for whole‐body energy homeostasis and plays an important role in metabolic and hormonal regulation. While healthy WAT undergoes controlled expansion and contraction to meet the body's requirements, dysfunctional WAT in conditions like obesity is characterized by excessive tissue expansion, alterations in lipid ...
Solsona-Vilarrasa E, Vousden KH.
europepmc +3 more sources
Effects of a Phosphodiesterase inhibitor on the Browning of Adipose Tissue in Mice
Biomedicines, 2022 Cilostazol is a selective inhibitor of phosphodiesterase type 3 (PDE3) that increases intracellular cyclic adenosine monophosphate (cAMP), which plays a critical role in the development of the beige phenotype and the activation of its thermogenic program
Da Hea Seo +6 more
doaj +1 more source
Fatty Acid Metabolite Profiling Reveals Oxylipins as Markers of Brown but Not Brite Adipose Tissue
Frontiers in Endocrinology, 2020 Metabolites of omega-6 and omega-3 polyunsaturated fatty acids are important signaling molecules implicated in the control of adipogenesis and energy balance regulation.
Sebastian Dieckmann +14 more
doaj +1 more source