Results 71 to 80 of about 254,914 (259)
MedCommWhite adipose tissue is not only a highly heterogeneous organ containing various cells, such as adipocytes, adipose stem and progenitor cells, and immune cells, but also an endocrine organ that is highly important for regulating metabolic and immune ...
Zi‐Han Yang +7 more
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Characteristics and mechanisms of subcutaneous and visceral adipose tissue aging
Chinese Journal of Plastic and Reconstructive SurgeryAging is one of the most significant health challenges worldwide and is a primary cause of chronic diseases and physiological decline. Among the myriad changes that occur with aging, alterations in adipose tissue distribution and function have gained ...
Peng Xu, Yikai Wang, Kai Liu
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Lipids in Health and Disease, 2020 Obesity exhibits a correlation with metabolic inflammation and endoplasmic reticulum stress, promoting the progression of metabolic disease such as diabetes, hyperlipidemia, hyperuricemia and so on.
Yunjia Li, Ke Yun, Runqing Mu
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An integrated single cell and spatial transcriptomic map of human white adipose tissue
Nature Communications, 2023 Single-cell studies of human white adipose tissue (WAT) provide insights into the specialized cell types in the tissue. Here the authors combine publicly available and newly generated high-resolution and bulk transcriptomic results from multiple human ...
Lucas Massier +27 more
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Adipose tissue: colors, depots and functions
Ожирение и метаболизм, 2021 Obesity is a chronic disease characterized by excessive accumulation of adipose tissue. The prevalence of obesity and associated diseases has prompted researchers to expand the study of the biology of adipose tissue.
T. I. Romantsova
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Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice [PDF]
, 2017 The increased prevalence of obesity and its cardiometabolic implications demonstrates the imperative to identify novel therapeutic targets able to effect meaningful metabolic changes in this population.
Adams +34 more
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Immune Cells Gate White Adipose Tissue Expansion [PDF]
Endocrinology, 2019 The immune system plays a critical role in white adipose tissue (WAT) energy homeostasis and, by extension, whole-body metabolism. Substantial evidence from mouse and human studies firmly establishes that insulin sensitivity deteriorates as a result of subclinical inflammation in the adipose tissue of individuals with diabetes.
Aaron R Cox +3 more
openaire +2 more sources
Dielectric properties measurements of brown and white adipose tissue in rats from 0.5 to 10 GHz [PDF]
, 2016 Brown adipose tissue (BAT) plays an important role in whole body metabolism and with appropriate stimulus could potentially mediate weight gain and insulin sensitivity.
Colebeck, E. +6 more
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Glucocorticoid Receptor and Adipocyte Biology. [PDF]
, 2018 Glucocorticoids are steroid hormones that play a key role in metabolic adaptations during stress, such as fasting and starvation, in order to maintain plasma glucose levels.
Harris, Charles A +2 more
core +2 more sources
Dexamethasone Inhibits White Adipose Tissue Browning
International Journal of Molecular SciencesWhite adipose tissue (WAT) regulates energy balance through energy storage, adipokines secretion and the thermogenesis process. Beige adipocytes are responsible for WAT thermogenesis. They are generated by adipogenesis or transdifferentiation during cold or β3-adrenergic agonist stimulus through a process called browning.
Alejandra Paula Giordano +8 more
openaire +4 more sources