Results 71 to 80 of about 499,911 (300)

Sex matters: The effects of biological sex on adipose tissue biology and energy metabolism

open access: yesRedox Biology, 2017
Adipose tissue is a complex and multi-faceted organ. It responds dynamically to internal and external stimuli, depending on the developmental stage and activity of the organism.
Teresa G. Valencak   +2 more
doaj   +1 more source

Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice [PDF]

open access: yes, 2017
The increased prevalence of obesity and its cardiometabolic implications demonstrates the imperative to identify novel therapeutic targets able to effect meaningful metabolic changes in this population.
Adams   +34 more
core   +1 more source

TGFBI remodels adipose metabolism by regulating the Notch-1 signaling pathway

open access: yesExperimental and Molecular Medicine, 2023
Fat metabolism: protecting against obesity-related metabolic disorders Studying a protein called TGFBI, which regulates adipose expansion, may help the development of new approaches to protect against obesity and related metabolic disorders such as type ...
Seul Gi Lee   +10 more
doaj   +1 more source

Therapeutic targeting of white adipose tissue metabolic dysfunction in obesity: mechanisms and opportunities

open access: yesMedComm
White adipose tissue is not only a highly heterogeneous organ containing various cells, such as adipocytes, adipose stem and progenitor cells, and immune cells, but also an endocrine organ that is highly important for regulating metabolic and immune ...
Zi‐Han Yang   +7 more
doaj   +1 more source

Characteristics and mechanisms of subcutaneous and visceral adipose tissue aging

open access: yesChinese Journal of Plastic and Reconstructive Surgery
Aging is one of the most significant health challenges worldwide and is a primary cause of chronic diseases and physiological decline. Among the myriad changes that occur with aging, alterations in adipose tissue distribution and function have gained ...
Peng Xu, Yikai Wang, Kai Liu
doaj   +1 more source

Adipose tissue: colors, depots and functions

open access: yesОжирение и метаболизм, 2021
Obesity is a chronic disease characterized by excessive accumulation of adipose tissue. The prevalence of obesity and associated diseases has prompted researchers to expand the study of the biology of adipose tissue.
T. I. Romantsova
doaj   +1 more source

Metabolic effects of FGF-21: thermoregulation and beyond [PDF]

open access: yes, 2015
Fibroblast growth factor (FGF)-21, a member of the FGF family, is a novel hormone involved in the control of metabolism by modulating glucose homeostasis, insulin sensitivity, ketogenesis, and promoting adipose tissue “browning.” Recent studies ...
Celi, Francesco S.   +3 more
core   +3 more sources

Interleukin-6 induces fat loss in cancer cachexia by promoting white adipose tissue lipolysis and browning

open access: yesLipids in Health and Disease, 2018
Cancer cachexia is a progressive and multi-factorial metabolic syndrome characterized by loss of adipose tissue and skeletal muscle. White adipose tissue (WAT) lipolysis and white-to-brown transdifferentiation of WAT (WAT browning) are proposed to ...
Jun Han, Q. Meng, Lei Shen, Guohao Wu
semanticscholar   +1 more source

A percutaneous needle biopsy technique for sampling the supraclavicular brown adipose tissue depot of humans. [PDF]

open access: yes, 2015
Brown adipose tissue (BAT) has been proposed as a potential target tissue against obesity and its related metabolic complications. Although the molecular and functional characteristics of BAT have been intensively studied in rodents, only a few studies ...
Annamalai, P   +6 more
core   +2 more sources

Taurine-mediated browning of white adipose tissue is involved in its anti-obesity effect in mice

open access: yesJournal of Biological Chemistry, 2019
Taurine, a nonprotein amino acid, is widely distributed in almost all animal tissues. Ingestion of taurine helps to improve obesity and its related metabolic disorders.
Ying-ying Guo   +4 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy