Results 51 to 60 of about 3,431 (173)
Data in Brief, 2016 Mass spectrometry data collected in a study analyzing the effect of withaferin A (WA) on a mouse microglial (N9) cell line is presented in this article.
Malathi Narayan +2 more
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Withaferin A: a potential therapeutic agent against COVID-19 infection
Journal of Ovarian Research, 2020 The outbreak and continued spread of the novel coronavirus disease 2019 (COVID-19) is a preeminent global health threat that has resulted in the infection of over 11.5 million people worldwide.
Alex R. Straughn, Sham S. Kakar
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Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Molecular Cancer, 2010 Background Multidrug resistance (MDR) is a major obstacle in cancer treatment and is often the result of overexpression of the drug efflux protein, P-glycoprotein (P-gp), as a consequence of hyperactivation of NFκB, AP1 and Nrf2 transcription factors. In
Gerlo Sarah +7 more
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A comprehensive review of cancer‐induced cardiac wasting
British Journal of Pharmacology, EarlyView.Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena +5 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka +3 more
wiley +1 more source
Scientific ReportsWith the aging process of the global population and the development of medical technology, the cases of postoperative cognitive dysfunction (POCD) are also increasing.
Haijun Hu +7 more
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Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine
Molecules, 2009 Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and indigenous medicine for over 3,000 years.
Javier Palazón +4 more
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γ‐T3 Increases the Sensitization of Gastric Cancer Cells to OXA by a Regulation of ARHGAP29
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.γ‐T3 combined with oxaliplatin (OXA) inhibited the proliferation of gastric cancer cells by induction autophagy via ARHGAP29/GSK‐3β/β‐Catenin pathways. γ‐T3 combined with low‐dose of OXA could exert synergistic effects on induction autophagy‐related gastric cancer cell death, which is partially mediated by down‐regulation of the ARHGAP29/GSK‐3β/β ...
Hao Zhu +11 more
wiley +1 more source
Mediators of Inflammation, 2019 Despite the usefulness of glucocorticoids, they may cause hazardous side effects that limit their use. Searching for compounds that are as equally efficient as glucocorticoids, but with less side effects, the current study compared plant steroids, namely,
Mohamed A. Morsy +6 more
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