Results 41 to 50 of about 118,549,391 (165)
Effect of withanone and withaferin A purified from WSWE on S. globosa cells.
, 2022 [A, B] Mirror HPLC chromatograms of standard mix (black) and purified withanone (blue) (A)/withaferin A (B) recorded at 227 nm. [C, D] Dose response curves of withanone (A) and withaferin A (B) demonstrating anti-sporotrichotic effects against S. globosa
Acharya Balkrishna (5640038) +5 more
core +1 more source
Exploring the Multifaceted Therapeutic Potential of Withaferin A and Its Derivatives
Biomedicines, 2020 Withaferin A (WA), a manifold studied, C28-steroidal lactone withanolide found in Withania somnifera. Given its unique beneficial effects, it has gathered attention in the era of modern science.
Tapan Behl +7 more
doaj +1 more source
, 2022 Withaferin A, a natural steroidal lactone found in the extracts of Withania somnifera, is used extensively in traditional medicine and part of an ancient remedy in ayurvedic medicine.
Winssinger, Nicolas +5 more
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ISOLATION AND CHARACTERIZATION OF WITHAFERIN-A FROM THE WITHANIA SOMNIFERA (ASHWAGANDHA) [PDF]
, 2017 The research work is related to an improved process of isolation & characterization of Withaferin-A from withania somnifera (Sanskrit: Ashawagandha, English: Winter cherry).
Rakesh Kumar Jat +3 more
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Withaferin A ameliorates ovarian cancer-induced cachexia and proinflammatory signaling
Journal of Ovarian Research, 2019 Background Ovarian cancer is the fifth leading cause of cancer-related deaths amongst women in the United States. Cachexia is the primary cause of death in approximately 30% of cancer patients, and is often evidenced in ovarian cancer patients. We tested
Alex R. Straughn, Sham S. Kakar
doaj +1 more source
Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review. [PDF]
Phytother ResABSTRACT The preclinical evidence for the safety of ashwagandha ( Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports. Most studies and reviews conclude
Williamson EM, Brendler T.
europepmc +2 more sources
Vimentin as a potential therapeutic target in sorafenib resistant HepG2, a HCC model cell line [PDF]
Clinical and Molecular Hepatology, 2020 Background/Aims Hepatocellular carcinoma (HCC) is the most common liver cancer with high mortality rate in patients suffering from liver diseases. The drug of choice used in advanced-stage of HCC is sorafenib.
Ankita Makol +5 more
doaj +1 more source
Frontiers in Pharmacology, 2018 Pulmonary fibrosis (PF) is chronic lung disease with only two FDA approved clinically available drugs, with limited safety profile. Inadequate therapy motivated us to explore the effect of vimentin inhibitor Withaferin A, as an anti-fibrotic agent ...
Swarna Bale +3 more
doaj +1 more source
Withaferin-A displays enhanced anxiolytic efficacy without tolerance in rats following sub chronic administration [PDF]
, 2013 Withaferin-A dose-dependently (10 tob40 mg/kg) displayed anxiolytic activity, as measured by an increase in open arm exploration time in the elevated plus-maze (EPM), following intraperitoneal (i.p.) administration in rats.
Ghosh, AR, Khan, ZA
core +1 more source
Supplementary Table from Withaferin A Inhibits Fatty Acid Synthesis in Rat Mammary Tumors
, 2023 Supplementary Table from Withaferin A Inhibits Fatty Acid Synthesis in Rat Mammary ...
Krishna B. Singh (15111017) +3 more
core +1 more source