Results 61 to 70 of about 114,628,403 (161)
British Journal of Pharmacology, EarlyView.Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka +3 more
wiley +1 more source
Rapid and sensitive method for determination of withaferin-A in human plasma by HPLC
, 2011 Background: To develop and validate a rapid and sensitive high-performance liquid chromatographic method for determination of withaferin-A in human plasma.
Pankaj Patial, Vikram Gota
core +1 more source
Mediators of Inflammation, 2019 Despite the usefulness of glucocorticoids, they may cause hazardous side effects that limit their use. Searching for compounds that are as equally efficient as glucocorticoids, but with less side effects, the current study compared plant steroids, namely,
Mohamed A. Morsy +6 more
doaj +1 more source
Food Science &Nutrition, Volume 14, Issue 10, October 2026.This review contrasts the root and leaf of Withania somnifera (ashwagandha) across phytochemistry, clinical evidence, and regulatory context. Root preparations are dominated by withanolide A, D, and glyco‐withanolides, with multiple randomized controlled trials supporting reductions in stress, anxiety, and insomnia alongside a favorable safety profile.
Abhijit Dutta, Jang Bahadur Gupta
wiley +1 more source
Frontiers in Medicine, 2017 Visceral leishmaniasis (VL) causes fatal life-threatening disease, if left untreated. The current drugs have various limitations; hence, natural products from medicinal plants are being focused in search of new drugs to treat leishmaniasis.
Sambamurthy Chandrasekaran +3 more
doaj +1 more source
Nano Select, Volume 7, Issue 10, October 2026.Surface‐modified niosomes are introduced as multifunctional nanoparticles for precision tumor treatment that combine hydrophilic and lipophilic drug encapsulation with ligand‐based targeting via antibodies, peptides, transferrin, and folic acid. This modification leads to increased tumor selectivity, facilitates cell entry, and enables enhanced ...
Narges Sahraei +3 more
wiley +1 more source
Nanoencapsulation of Withaferin-A for the Treatment of Neurological Disorder [PDF]
, 2022 A better delivery mechanism is ensured by a superior formulation. This study is based on the fact that people believe in natural products more than chemical products.
Sonu Sharma, Dr. Viney Lather, Dr. Vikram Sharma
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Phytotherapy Research, Volume 40, Issue 10, Page 5951-5972, October 2026.ABSTRACT Withania somnifera (L.) Dunal (WS), commonly known as Ashwagandha, is a prominent medicinal herb in Ayurveda, with extensive therapeutic potential attributed to its diverse phytochemical profile. This review critically examines the immunomodulatory properties of WS, focusing on innate immune cell populations, including neutrophils, eosinophils,
Rana Yukta +9 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 18, 30 September 2026.MR identified phenylalanine as a causal PC risk factor (OR 1.18). A 5‐gene RF model (AUC 0.955) highlighted SLC6A14 as the top biomarker. Single‐cell analysis revealed epithelial–immune crosstalk. Molecular docking identified genistein (−9.1 kcal/mol) as a lead SLC6A14‐targeting compound.
Xing Liu +3 more
wiley +1 more source
Withaferin A promotes proliferation and migration of brain endothelial cells [PDF]
, 2016 Purpose: To investigate the effect of withaferin A (WFA) on the proliferation and migration of brain endothelial cells.Methods: BALB-5023 mouse microvascular cells were treated with a range of withaferin A (WFA) concentrations from 10 to 100 ng/mL ...
Huang, Li-An +3 more
core +1 more source