Results 81 to 90 of about 114,628,403 (161)
Phytotherapy Research, Volume 40, Issue 8, Page 4802-4812, August 2026.ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve +6 more
wiley +1 more source
Withaferin A is a Leptin Sensitizer with Strong Anti-Diabetic Properties in Mice
, 2018 The increasing global prevalence of obesity and its associated disorders point to an urgent need for the development of novel and effective therapeutic strategies that induce healthy weight loss.
Lee, Jaemin +7 more
core +1 more source
Withaferin-A: A Potential Anticancer Withanolide from \u3cem\u3eWithania somnifera\u3c/em\u3e (L.) Dun. [PDF]
, 2005 Withania somnifera (Ashwagandha) is a plant used in medicine from the time of Ayurveda, the ancient system of Indian medicine. The dried roots of the plant are used in the treatment of nervous and sexual disorders.
Singh, Amrit Pal
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The development of advanced high-capacity nanoparticle-based drug loading, precise targeting, low toxicity, and excellent biocompatibility is critical for improving cancer therapeutics.
Paulraj Arunkumar +2 more
core +1 more source
Chemical structures of withanone and withaferin A.
, 2013 Withanone is a C6, C7 epoxy compound (colored red) that has hydroxyl groups (colored green) on C5 and C17. On the other hand, withaferin A is a C5, C6 epoxy compound (colored red) with hydroxyl groups on C4 and C27 (colored green).
M. Uthayakumar (308967) +9 more
core +1 more source
Effect of withanone and withaferin A purified from WSWE on S. globosa cells.
, 2022 [A, B] Mirror HPLC chromatograms of standard mix (black) and purified withanone (blue) (A)/withaferin A (B) recorded at 227 nm. [C, D] Dose response curves of withanone (A) and withaferin A (B) demonstrating anti-sporotrichotic effects against S. globosa
Acharya Balkrishna (5640038) +5 more
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PROTECTIVE EFFECT OF WITHAFERIN-A ON MICRONUCLEUS FREQUENCY AND DETOXICATION AGENTS DURING EXPERIMENTAL ORAL CARCINOGENESIS [PDF]
, 2008 Our aim was to investigate the effect of Withaferin-A on bone marrow micronucleus frequency and buccal mucosa detoxication agents during 7, 12–dimethylbenz[a]anthracene (DMBA) induced hamster buccal pouch carcinogenesis.
Panjamurthy, K. +6 more
core
Withaferin A Associated Differential Regulation of Inflammatory Cytokines
Frontiers in Immunology, 2018 A role of inflammation-associated cytokines/chemokines has been implicated in a wide variety of human diseases. Here, we investigated the regulation of inflammatory cytokines released by monocyte-derived THP-1 cells following treatment with the dietary ...
Seema Dubey +5 more
doaj +1 more source
Obesity: Will withaferin win the war?
, 2016 A new study shows that withaferin A, a steroidal lactone isolated from Withania somnifera, can exert profound metabolic benefits in mice, including body-weight loss, reduced hepatic steatosis and improved glucose ...
Pfluger, P.T., Tschöp, M.H.
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Water-soluble Withaferin A polymer prodrugs via a drug-functionalized RAFT CTA approach
, 2019 To cope with the poor aqueous solubility of withaferin A, a broad-spectrum anti-cancer agent effective against therapy-resistant cancers, a polymer-drug conjugate was synthesized via a grafting-from-drug approach.
Vanden Berghe, Tom +8 more
core +1 more source