Results 101 to 110 of about 114,627,962 (212)

Data for: Profiling Withanolide A for Therapeutic Targets in Neurodegenerative Diseases

, 2019
This is the supporting information for the article by Crane et al, (2019) "Profiling Withanolide A for Therapeutic Targets in Neurodegenerative Diseases "
Erika Crane (7017518), Stephan Sieber (449608), Elma Mons (1763260), Angelo Vedani (2175378), Lydia Barth (7017524), Martin Smiesko (1637800), Wolfgang Heydenreuter (6184424), Karl Gademann (1233621), Jan Vormacka (7017521), Alex Odermatt (27423), Katharina Beck (5204546), Petra Strajhar (7017515), Markus Neuburger (1233615)   +12 more
core   +2 more sources

Effect of Withanolide A on oxidative stress markers.

, 2014
Administration of Withanolide A decreases the hypoxia induced elevated level of reactive oxygen species, lipid peroxidation and GSH in hippocampus. Data expressed as percentage change taking normoxic value as 100% and represents Mean ± SEM. ‘a’ denotes p≤
Pradeep Kumar Naik (436805), Jayanta Kumar Sahu (643672), Vishal Jain (14349), Govindasamy Ilavazhagan (414361), Iswar Baitharu (414359), Satya Narayan Deep (643670), Sabita Shroff (643671)   +6 more
core   +1 more source

Endophytes of Withania somnifera modulate in planta content and the site of withanolide biosynthesis

, 2018
Tissue specific biosynthesis of secondary metabolites is a distinguished feature of medicinal plants. Withania somnifera, source of pharmaceutically important withanolides biosynthesizes withaferin-A in leaves and withanolide-A in roots.
Sumit Soni, Shiv S. Pandey, Sucheta Singh, Madhumita Srivastava, M. M. Gupta, Harshita Pandey, Tania Ray, Suchitra Banerjee, Alok Kalra, Alok Pandey, Karuna Shanker, C. S. Vivek Babu   +11 more
core   +1 more source

Shoden promotes Relief from stress and anxiety: A randomized, double-blind, placebo-controlled study on healthy subjects with high stress levels

Heliyon
Background: This randomized placebo-controlled study examined the effect of ashwagandha root and leaf extract 60 mg (AE60) and 120 mg (AE120) (35 % withanolide glycosides, Shoden) in physically healthy subjects with higher stress and anxiety.
Deo Nidhi Mishra, Manoj Kumar
doaj   +1 more source

Withanolide Artifacts Formed in Methanol

, 2016
Methanol solutions of the main withanolides (6–8) naturally present in Physalis longifolia yielded five artificial withanolides (1–5), including three new compounds (1–3).
Robert J. Gallagher (1880416), Barbara N. Timmermann (1502962), Huaping Zhang (1828219), Cong-Mei Cao (228099)   +3 more
core   +1 more source

Withanolide glycosides from Physalis volubilis

Fitoterapia
The study of the acetone and methanol extracts of the stems, leaves, and flowers of Physalis volubilis led to obtain four withanolide glycosides (4, 6, 10, and 14). Compounds 1-3, 13, 15, and a sterol glycoside were also isolated. The structures were established by analysis of spectroscopic and spectrometric data, and by chemical transformations.
Ana-L, Pérez-Castorena, Tonantzin G, Anguheven L, M Azucena, Martínez R, Jesús, Morales-Jiménez, Emma, Maldonado, Mahinda, Martínez   +5 more
openaire   +2 more sources

Estimation of withanolide A in diverse genotypes of Ashwagandha Withania somnifera (L.) Dunal [PDF]

, 2019
212-217Withania somnifera (L.) Dunal (Fam. Solanaceae) commonly known as Ashwagandha has been used in traditional Indian medicine system from ancient times. Roots of the plant are being used in the preparation of many Ayurvedic medicines for treatment of
Joshi, Arunabh, Jain, Rohit, Jain, Devendra, Chauhan, Surya   +3 more
core  

Metabolic clustering of a core collection of Indian ginseng Withania somnifera Dunal through DNA, isoenzyme, polypeptide and withanolide profile diversity

, 2009
Withania somnifera is one of the most important medicinal plants of Ayurveda and finds extensive uses in Indian traditional herbal preparations. In this investigation, selected accessions of the plant were examined for diversity through RAPDs, isoenzymes,
Sangwan, Rajender S., Misra, Laxmi N., Sangwan, Neelam S., Chaurasiya, Narayan D., Tuli, Rakesh   +4 more
core   +1 more source

Schematic diagram showing Withanolide A mediated modulation of glutathione biosynthesis and neuroprotection during hypobaric hypoxia.

, 2014
Schematic diagram showing Withanolide A mediated modulation of glutathione biosynthesis and neuroprotection during hypobaric hypoxia.
Pradeep Kumar Naik (436805), Jayanta Kumar Sahu (643672), Vishal Jain (14349), Govindasamy Ilavazhagan (414361), Iswar Baitharu (414359), Satya Narayan Deep (643670), Sabita Shroff (643671)   +6 more
core   +1 more source

Antiviral Activity of Withanolide A Against Different Infectivity Phases of Dengue Virus Serotype 2 in Vero Cell Line

Dengue fever is caused by the Aedes mosquito-borne dengue virus, which is a global threat with 400 million cases reported annually and 5–20% mortality rate. Currently, there is no effective treatment available for dengue fever.
Lee, Michelle Felicia *, Batumalaie, Kalaivani, Mahendran Sekar, Fuloria, Neeraj Kumar, Neeraj Kumar Fuloria, Poh, Chit Laa *, Nafees Ahemad, Shivkanya Fuloria, Subramaniyan, Vetriselvan, Chit, Laa Poh, Sekar, Mahendran, Ahemad, Nafees, Kalaivani Batumalaie, Wu, Yuan Seng *, Michelle felicia lee, Yuan, Seng Wu, Lujin Al Quwatli, Vetriselvan Subramaniyan, Al Quwatli, Lujin, Fuloria, Shivkanya, Sarke, Moklesur Rahman, Moklesur Rahman Sarke, Rhanye Mac Guad, Guad, Rhanye Mac   +23 more
core   +1 more source