Results 101 to 110 of about 3,164 (224)

Effect of Withanolide A on free radical scavenging enzyme system. [PDF]

, 2014
Withanolide A administration during hypoxic exposure increases hypoxia induced decreased activity of glutathione reductase, glutathione peroxidase, glutathione s transferase and superoxide dismutase in hippocampus.
Pradeep Kumar Naik (436805), Jayanta Kumar Sahu (643672), Vishal Jain (14349), Govindasamy Ilavazhagan (414361), Iswar Baitharu (414359), Satya Narayan Deep (643670), Sabita Shroff (643671)   +6 more
core   +1 more source

Effect of Inoculum Density and Different Media on the Growth of Hairy Roots and Production of Withanolide-A from Withaniasomnifera [PDF]

, 2017
Withaniasomnifera (L.) Dunal. (Indian ginseng) is one of the most important medicinal plants used as a crude drug for its preventive and therapeutic purposes.
H N Murthy, Praveen Nagella, Nagella, Praveen, Murthy, H N   +3 more
core   +2 more sources

Natural Withanolides in the Treatment of Chronic Diseases [PDF]

, 2016
Withanolides, and in particular extracts from Withania somnifera, have been used for over 3,000 years in traditional Ayurvedic and Unani Indian medical systems as well as within several other Asian countries. Traditionally, the extracts were ascribed a wide range of pharmacologic properties with corresponding medical uses, including adaptogenic ...
White, Peter T., Subramanian, Chitra, Motiwala, Hashim F., Cohen, Mark S.   +3 more
openaire   +2 more sources

Protective effects of Withanolide A from HIV-1_Ba-L (clade B) infection, Cocaine and METH treated in SK-N-MC cells. [PDF]

, 2014
MTT assay showing the inhibition of % cell viability in HIV-1Ba-L (clade B), Cocaine and METH treated and their reversal by Withanolide A. Withanolide A alone showed significant increase in cell viability.
Thangavel Samikkannu (471645), Madhavan P. N. Nair (404586), Adriana Yndart (404585), Venkata Subba Rao Atluri (404582), Kesava Rao Venkata Kurapati (471644), Elena Kaftanovskaya (664371)   +5 more
core   +1 more source

Structure-based virtual screening methods for the identification of novel phytochemical inhibitors targeting furin protease for the management of COVID-19

Frontiers in Cellular and Infection Microbiology
The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, is a highly contagious respiratory disease with widespread societal impact.
Prashant Kumar Tiwari, Mandeep Chouhan, Richa Mishra, Saurabh Gupta, Anis Ahmad Chaudhary, Mohammed Al-Zharani, Ashraf Ahmed Qurtam, Fahd A. Nasr, Niraj Kumar Jha, Niraj Kumar Jha, Niraj Kumar Jha, Kumud Pant, Mukesh Kumar, Sanjay Kumar   +13 more
doaj   +1 more source

Synergistic activity of nootropic herbs as potent therapeutics for Alzheimer's disease: A cheminformatics, pharmacokinetics, and system pharmacology approach

Journal of Alzheimer's Disease Reports
Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder, which subdues over 55 million people and finding a cure, still remains disenchanting.
Reiya Bosco Don Bosco, Johnson Retnaraj Samuel Selvan Christyraj, Beryl Vedha Yesudhason   +2 more
doaj   +1 more source

Molecular Modeling, NOESY NMR, and the Structure of Nicandrenone Isolated from (Solanaceae)

Natural Product Communications, 2009
The configuration and conformation of nicandrenone, isolated from Nicandra physalodes , are described using molecular modeling and NMR NOESY techniques.
Patrick F. Jonas, Geoffrey A. Cordell
doaj   +1 more source

Evaluation of the bioavailability of major withanolides of Withania somnifera using an in vitro absorption model system

Journal of Advanced Pharmaceutical Technology & Research, 2015
Withania somnifera (L.) Dunal, shows several pharmacological properties which are attributed mainly to the withanolides present in the root. The efficacy of medicinally active withanolides constituents depends on the absorption and transportation through
Santosh T Devkar, Amit D Kandhare, Brian D Sloley, Suresh D Jagtap, James Lin, Yun K Tam, Surendra S Katyare, Subhash L Bodhankar, Mahabaleshwar V Hegde   +8 more
doaj   +1 more source

The Total Synthesis of Analogues of Withanolide F [PDF]

, 2014
The total synthesis of analogues of withanolide F I, a highly oxygenated C-28 steroidal lactone natural product isolated from the leaves of the plant Withania adpressa is discussed herein. Chapter 1 describes the classification of the withanolides, their
Manicassamy, Laura
core  

Withanolide A is inherently de novo biosynthesized in roots of the medicinal plant Ashwagandha (Withania somnifera) [PDF]

, 2008
Ashwagandha (Withania somnifera Dunal., Solanaceae) is one of the most reputed medicinal plants of Ayurveda, the traditional medical system. Several of its traditionally proclaimed medicinal properties have been corroborated by recent molecular ...
Lal, Payare, Misra, Laxminarain, Sangwan, Neelam Singh, Sangwan, Rajender Singh, Tuli, Rakesh, Chaurasiya, Narayan Das   +5 more
core   +1 more source