Results 91 to 100 of about 3,164 (224)
ABSTRACT Background Phytogenic feed additives have shown potential in enhancing nutrient utilization, improving performance and mitigating pathogenic challenges in Sonali chicken. Objective The goal of the current study was to assess how Shatamuli (Asparagus racemosus) and Ashwagandha (Withania somnifera) affected the Sonali chickens' growth ...
Ayesha Siddika +5 more
wiley +1 more source
Withanolide Artifacts Formed in Methanol [PDF]
Methanol solutions of the main withanolides (6–8) naturally present in Physalis longifolia yielded five artificial withanolides (1–5), including three new compounds (1–3).
Robert J. Gallagher (1880416) +3 more
core +1 more source
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima +15 more
wiley +1 more source
Schematic diagram showing Withanolide A mediated modulation of glutathione biosynthesis and neuroprotection during hypobaric hypoxia. [PDF]
Schematic diagram showing Withanolide A mediated modulation of glutathione biosynthesis and neuroprotection during hypobaric hypoxia.
Pradeep Kumar Naik (436805) +6 more
core +1 more source
ABSTRACT Dysregulation of the nuclear factor kappa B (NF‐κB) signaling pathway is closely associated with inflammation‐driven carcinogenesis, tumor progression and resistance to conventional therapies. Sustained NF‐κB activation enhances malignant cell survival, proliferation and immune evasion by promoting proinflammatory and antiapoptotic gene ...
Maria Sharif +10 more
wiley +1 more source
Antiviral Activity of Withanolide A Against Different Infectivity Phases of Dengue Virus Serotype 2 in Vero Cell Line [PDF]
Dengue fever is caused by the Aedes mosquito-borne dengue virus, which is a global threat with 400 million cases reported annually and 5–20% mortality rate. Currently, there is no effective treatment available for dengue fever.
Lee, Michelle Felicia * +23 more
core +1 more source
Metabolic clustering of a core collection of Indian ginseng Withania somnifera Dunal through DNA, isoenzyme, polypeptide and withanolide profile diversity [PDF]
Withania somnifera is one of the most important medicinal plants of Ayurveda and finds extensive uses in Indian traditional herbal preparations. In this investigation, selected accessions of the plant were examined for diversity through RAPDs, isoenzymes,
Sangwan, Rajender S. +4 more
core +1 more source
Withania somnifera (WS) or Ashwagandha is valued for its anti‐inflammatory, antioxidant, adaptogenic, and memory‐enhancing properties. This randomized, placebo‐controlled and double‐blind study assessed the safety of standardized WS root extract in healthy adult participants over 180 days. The study concluded that WS root extract (200 mg capsules twice
Narendra Vaidya +7 more
wiley +1 more source
Withametelin: a biologically active withanolide in cancer, inflammation, pain and depression
Withanolides are natural medicinal agents whose safety and therapeutic profiles make them valuable to mankind. Among multiple withanolides, withametelin is underexplored.
Muhammad Waleed Baig +5 more
doaj +1 more source
Elucidating the active interaction mechanism of phytochemicals withanolide and withanoside derivatives with human serum albumin - Fig 1 [PDF]
The structure of withanolide A (C28H38O6-470.6Da), withanolide B (C28H38O5-454.6Da), withanoside IV (C40H62O15-782.9Da) and withanoside V (C40H62O14-766.9Da).
Arijit Sarkar (5942156) +3 more
core +1 more source

