Results 81 to 90 of about 3,164 (224)

Evaluation of Withaferin A Content in Withania somnifera Using NMR and HPLC: A Comparative Assessment of Traditional and PCSL Extraction Methods

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
A comparative evaluation of traditional aqueous extractions and innovative pressurised cyclic solid–liquid extraction is presented for Withania somnifera leaves. Quantitative NMR, validated by HPLC, reveals a markedly enhanced preservation and recovery of withaferin A using PCSL.
Silvana Pedatella, Maria Chiara Di Meo, Daniele Naviglio, Gionata De Vico, Armando Zarrelli   +4 more
wiley   +1 more source

Endophytes of Withania somnifera modulate in planta content and the site of withanolide biosynthesis [PDF]

, 2018
Tissue specific biosynthesis of secondary metabolites is a distinguished feature of medicinal plants. Withania somnifera, source of pharmaceutically important withanolides biosynthesizes withaferin-A in leaves and withanolide-A in roots.
Sumit Soni, Shiv S. Pandey, Sucheta Singh, Madhumita Srivastava, M. M. Gupta, Harshita Pandey, Tania Ray, Suchitra Banerjee, Alok Kalra, Alok Pandey, Karuna Shanker, C. S. Vivek Babu   +11 more
core   +1 more source

Atomic Force Microscopic (AFM) studies to visualize alteration in HSA molecule topology in presence of withanolide and withanoside derivatives at 10 μM resolution. [PDF]

, 2018
(A) Only HSA (B) HSA+withanolide A (C) HSA+withanolide B (D) HSA+withanolide IV and (E) HSA+withanolide V.
Arijit Sarkar (5942156), Monika Kallubai (618436), Shreya Dubey (3820303), Rajagopal Subramanyam (297691)   +3 more
core   +1 more source

Pharmacological Effects of withanolides [PDF]

Open Access Journal of Complementary & Alternative Medicine, 2019
Withania somnifera (L.) Dunal (Family, Solanaceae) commonly known as Ashwgandha or winter cherry is one of the top medicinal herbs used in Ayurveda-the holistic system of Indian medicine.
openaire   +1 more source

Alternative Approaches and Plant‐Based Remedies for Livestock Health Management Among the Batswana of Southern Africa: A Review

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
ABSTRACT Due to limited access to, and the high cost of conventional veterinary services, Batswana communities often rely on ethnoveterinary practices for livestock health management. This review provides an in‐depth analysis on the ethnoveterinary uses, biological properties and safety assessment of plants utilised in livestock husbandry. A systematic
Tswelelopele G. Mpolokeng, Ndzalama Shikwambana, Mompati V. Chakale, John A. Asong, Lyndy J. McGaw, Stephen O. Amoo, Nqobile A. Masondo, Adeyemi O. Aremu   +7 more
wiley   +1 more source

Molecular docking studies of various bioactive molecules from Withania somnifera against bronchial asthma

Current Issues in Pharmacy and Medical Sciences
Asthma is a complex respiratory disorder characterized by chronic inflammation and hyperresponsiveness of the bronchial airways. Despite the availability of effective treatments and diagnostic methods, some patients remain symptomatic and exhibit a poor
Nafaa H. Ali, Khursheed A. Sheikh, Maaz Naqvi, Sana Rehman, Kavita Gulati, Arunabha Ray   +5 more
doaj   +1 more source

Antitumor effect of withanolide D: a scoping review protocol [PDF]

This scoping review aims to identify studies that have investigated the antitumor effects of withanolide D and map the main ...
Karuza Maria Aves Pereira, Sthefane Gomes Feitosa, Denis Francisco Gonçalves de Oliveira   +2 more
core   +1 more source

Withania somnifera Root Extract Ameliorates PTU‐Induced Hypothyroidism by Regulating Hormone Levels and Gene Expression in Rats

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Graphical abstract for the integrated in silico and in vivo approach demonstrating the Methanolic extract of Withania somnifera root ameliorated PTU‐induced hypothyroidism through the regulation of thyroid hormone levels, gene expression, and thyroid histopathology.
Md. Saud Hossain, Md. Shah Poran Shuvo, M. Maruf Hasan Talukder, Shahidullah, Sumaia Jannat, S. M. Riaduzzaman Niaz, Md Sohel, Md. Khairul Islam   +7 more
wiley   +1 more source

Nutrigenomic Potentials of Phytobiotics Against Heat Stress and Allied Afflictions in Livestock Species–An In Silico Supported Review

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Heat stress impairs livestock performance through oxidative stress, immune dysregulation, and reduced productivity. Phytobiotics act as natural mitigators with antioxidant, anti‐inflammatory, antimicrobial, and gut‐modulatory effects. Mechanistically, they regulate HSPs, Nrf2, NF‐κB, and MAPK pathways.
Xiaoyan Wang, Ting Yuan, Muhammad Asif Arain, Mohammed Al‐Rasheed, Aftab Shaukat   +4 more
wiley   +1 more source

Molecular Mechanism of Mulberrin Regulating Lipid Metabolism Homeostasis Based on the Gut–Liver Axis Fiaf/AMPK Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
The molecular mechanism for mulberrin regulating lipid metabolism homeostasis. ABSTRACT Lipid metabolism disorders and the induced metabolic diseases have risen to become one of the primary public health issues. Our preliminary experimental results confirmed that mulberry leaf flavonoid extract exhibited efficacy in lipid metabolism regulation; the ...
Qian Li, Daorui Pang, Erna Li, Dongxu Xing, Fan Liu, Li Wang, Yuxiao Zou   +6 more
wiley   +1 more source