Results 81 to 90 of about 114,627,962 (212)

Pubescenol, a new withanolide from Physalis pubescence

, 1985
The isolation from Physalis pubescence of a new withanolide (now named pubescenol) and physalin E and its acetate is reported. The structure of pubescenol was shown to be 2,3-dihydro-4α ,7α -dihydroxy-1-oxo-24α ,25α -epoxywithanolide on the basis of its ...
Sambi Reddy, K., Matsuura, Teruo, Ramachandra Row, L.   +2 more
core   +1 more source

Molecular docking studies of various bioactive molecules from Withania somnifera against bronchial asthma

Current Issues in Pharmacy and Medical Sciences
Asthma is a complex respiratory disorder characterized by chronic inflammation and hyperresponsiveness of the bronchial airways. Despite the availability of effective treatments and diagnostic methods, some patients remain symptomatic and exhibit a poor
Nafaa H. Ali, Khursheed A. Sheikh, Maaz Naqvi, Sana Rehman, Kavita Gulati, Arunabha Ray   +5 more
doaj   +1 more source

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

Phytotherapy Research, Volume 40, Issue 8, Page 5005-5015, August 2026.
ABSTRACT Ashwagandha ( Withania somnifera ) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale, Jaising Salve, John Ademola, Jose Parraca, Deepak Langade   +4 more
wiley   +1 more source

A new antifeedant withanolide from Jaborosa lanigera [PDF]

, 2007
A new trechonolide-type withanolide, jaborosolactol, possessing a hemiketal ring system and a 5-membered lactol, has been isolated from the aerial parts of Jaborosa lanigera.
Biurrun, F.N., Cirigliano, A.M., Tettamanzi, M.C.   +2 more
core   +2 more sources

Laser‐Enabled Biotechnology Platforms for Climate‐Resilient Crop Production: Mechanistic Insights and Future Prospects

Food and Energy Security, Volume 15, Issue 4, July/August 2026.
ABSTRACT Climate change poses a major threat to global food security through extreme weather events, expanding pathogen ranges, and increased agrochemical dependency. This review highlights the emerging role of laser biotechnology as a sustainable and precise strategy to enhance crop resilience and productivity under climate stress.
Temoor Ahmed, Yumeng Lei, Muhammad Noman, Zhitao Li, Gabrijel Ondrasek, Muhammad Shafiq Shahid, Branko Petrinec, Xingjiang Qi, Bin Li, Yetong Qi   +9 more
wiley   +1 more source

Ashwagandha Root Extract and Its Potential Modulation of CCN1‐Associated Pathways in Sensitive‐Skin Aging

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Cellular Communication Network Factor 1 (CCN1) has been identified as a key regulator of oxidative stress‐induced skin aging and sensitivity. Ashwagandha root extract (ARE) is a promising candidate for modulating CCN1‐associated pathways. Aims To investigate whether ARE can mitigate sensitive‐skin aging by modulating CCN1 expression
Liying Kang, Yanhong Liu, Yuchen Xin, Lin Geng, Shaochun Cai, Jianfang Luo, Shaojie Gu, Shuangyan Wang, Zhiting Zhang, Yan Huang, Guixuan Zhou, Li Ye, Dongcui Li, Naisheng Jiang   +13 more
wiley   +1 more source

Evaluation of Withaferin A Content in Withania somnifera Using NMR and HPLC: A Comparative Assessment of Traditional and PCSL Extraction Methods

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
A comparative evaluation of traditional aqueous extractions and innovative pressurised cyclic solid–liquid extraction is presented for Withania somnifera leaves. Quantitative NMR, validated by HPLC, reveals a markedly enhanced preservation and recovery of withaferin A using PCSL.
Silvana Pedatella, Maria Chiara Di Meo, Daniele Naviglio, Gionata De Vico, Armando Zarrelli   +4 more
wiley   +1 more source

A Novel Withanolide Glucoside from the Rhizomes of Dioscorea panthaica

, 2013
A novel withanolide type C-28-steroid saponin, named dioscolide glucoside, was isolated from the rhizomes of Dioscorea panthaica Prain et Buckill. The structure was elucidated as (20S,22R,24R,25S)-1-oxo-2 alpha,3 alpha;6 alpha,7 alpha-diepoxy-5 alpha,16 ...
Wang Xiaoling, Liang Jian, Shan Xiaoqing, Ding Lisheng, Peng Shulin   +4 more
core  

Evolution of withanolide biosynthesis in nightshades

Withanolides are a diverse class of defensive metabolites produced by multiple clades within the nightshade family (Solanaceae). To evaluate whether withanolide biosynthesis originated independently across these lineages, we investigated the evolutionary
Saleh Alseekh, Sofía Rojas Contreras, Santiago Perez, Eva Knoch, Rocío Deanna, Federico Roda, Stacey D. Smith, Alisdair Fernie   +7 more
core   +1 more source

Elucidating the active interaction mechanism of phytochemicals withanolide and withanoside derivatives with human serum albumin - Fig 7

, 2018
Molecular docking studies between HSA and withanolide A, withanolide B, withanoside IV and withanoside V showed that the minimum binding energy conformer is very close to the experimentally determined values.
Arijit Sarkar (5942156), Monika Kallubai (618436), Shreya Dubey (3820303), Rajagopal Subramanyam (297691)   +3 more
core   +1 more source