Results 61 to 70 of about 23,202,835 (216)

Ashwagandha Root Extract and Its Potential Modulation of CCN1‐Associated Pathways in Sensitive‐Skin Aging

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Cellular Communication Network Factor 1 (CCN1) has been identified as a key regulator of oxidative stress‐induced skin aging and sensitivity. Ashwagandha root extract (ARE) is a promising candidate for modulating CCN1‐associated pathways. Aims To investigate whether ARE can mitigate sensitive‐skin aging by modulating CCN1 expression
Liying Kang, Yanhong Liu, Yuchen Xin, Lin Geng, Shaochun Cai, Jianfang Luo, Shaojie Gu, Shuangyan Wang, Zhiting Zhang, Yan Huang, Guixuan Zhou, Li Ye, Dongcui Li, Naisheng Jiang   +13 more
wiley   +1 more source

Evaluation of Withaferin A Content in Withania somnifera Using NMR and HPLC: A Comparative Assessment of Traditional and PCSL Extraction Methods

Chemistry &Biodiversity, Volume 23, Issue 6, June 2026.
A comparative evaluation of traditional aqueous extractions and innovative pressurised cyclic solid–liquid extraction is presented for Withania somnifera leaves. Quantitative NMR, validated by HPLC, reveals a markedly enhanced preservation and recovery of withaferin A using PCSL.
Silvana Pedatella, Maria Chiara Di Meo, Daniele Naviglio, Gionata De Vico, Armando Zarrelli   +4 more
wiley   +1 more source

Pharmacological Effects of withanolides [PDF]

Open Access Journal of Complementary & Alternative Medicine, 2019
Withania somnifera (L.) Dunal (Family, Solanaceae) commonly known as Ashwgandha or winter cherry is one of the top medicinal herbs used in Ayurveda-the holistic system of Indian medicine.
openaire   +1 more source

Molecular docking studies of various bioactive molecules from Withania somnifera against bronchial asthma

Current Issues in Pharmacy and Medical Sciences
Asthma is a complex respiratory disorder characterized by chronic inflammation and hyperresponsiveness of the bronchial airways. Despite the availability of effective treatments and diagnostic methods, some patients remain symptomatic and exhibit a poor
Nafaa H. Ali, Khursheed A. Sheikh, Maaz Naqvi, Sana Rehman, Kavita Gulati, Arunabha Ray   +5 more
doaj   +1 more source

Alternative Approaches and Plant‐Based Remedies for Livestock Health Management Among the Batswana of Southern Africa: A Review

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
ABSTRACT Due to limited access to, and the high cost of conventional veterinary services, Batswana communities often rely on ethnoveterinary practices for livestock health management. This review provides an in‐depth analysis on the ethnoveterinary uses, biological properties and safety assessment of plants utilised in livestock husbandry. A systematic
Tswelelopele G. Mpolokeng, Ndzalama Shikwambana, Mompati V. Chakale, John A. Asong, Lyndy J. McGaw, Stephen O. Amoo, Nqobile A. Masondo, Adeyemi O. Aremu   +7 more
wiley   +1 more source

Withania somnifera Root Extract Ameliorates PTU‐Induced Hypothyroidism by Regulating Hormone Levels and Gene Expression in Rats

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Graphical abstract for the integrated in silico and in vivo approach demonstrating the Methanolic extract of Withania somnifera root ameliorated PTU‐induced hypothyroidism through the regulation of thyroid hormone levels, gene expression, and thyroid histopathology.
Md. Saud Hossain, Md. Shah Poran Shuvo, M. Maruf Hasan Talukder, Shahidullah, Sumaia Jannat, S. M. Riaduzzaman Niaz, Md Sohel, Md. Khairul Islam   +7 more
wiley   +1 more source

Nutrigenomic Potentials of Phytobiotics Against Heat Stress and Allied Afflictions in Livestock Species–An In Silico Supported Review

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
Heat stress impairs livestock performance through oxidative stress, immune dysregulation, and reduced productivity. Phytobiotics act as natural mitigators with antioxidant, anti‐inflammatory, antimicrobial, and gut‐modulatory effects. Mechanistically, they regulate HSPs, Nrf2, NF‐κB, and MAPK pathways.
Xiaoyan Wang, Ting Yuan, Muhammad Asif Arain, Mohammed Al‐Rasheed, Aftab Shaukat   +4 more
wiley   +1 more source

Molecular Mechanism of Mulberrin Regulating Lipid Metabolism Homeostasis Based on the Gut–Liver Axis Fiaf/AMPK Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
The molecular mechanism for mulberrin regulating lipid metabolism homeostasis. ABSTRACT Lipid metabolism disorders and the induced metabolic diseases have risen to become one of the primary public health issues. Our preliminary experimental results confirmed that mulberry leaf flavonoid extract exhibited efficacy in lipid metabolism regulation; the ...
Qian Li, Daorui Pang, Erna Li, Dongxu Xing, Fan Liu, Li Wang, Yuxiao Zou   +6 more
wiley   +1 more source

The Impacts of Shatamuli, Ashwagandha and their Combination on Growth Performance, Faecal Microbial Population and Blood Parameters in Sonali Chickens

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
ABSTRACT Background Phytogenic feed additives have shown potential in enhancing nutrient utilization, improving performance and mitigating pathogenic challenges in Sonali chicken. Objective The goal of the current study was to assess how Shatamuli (Asparagus racemosus) and Ashwagandha (Withania somnifera) affected the Sonali chickens' growth ...
Ayesha Siddika, Md. Ahsan Habib, Ummay Salma, Md. Nurul Amin, Sabbir Hossen Sabuz, Md Abdur Rahman Toha   +5 more
wiley   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, Volume 7, Issue 1, January 2026.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source