Results 51 to 60 of about 114,627,962 (212)
Phytotherapy Research, EarlyView.Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli +6 more
wiley +1 more source
Enhanced biosynthesis of withanolides by elicitation and precursor feeding in cell suspension culture of Withania somnifera (L.) Dunal in shake-flask culture and bioreactor. [PDF]
PLoS ONE, 2014 The present study investigated the biosynthesis of major and minor withanolides of Withania somnifera in cell suspension culture using shake-flask culture and bioreactor by exploiting elicitation and precursor feeding strategies.
Ganeshan Sivanandhan +3 more
doaj +1 more source
Novel approaches for drug development against chronic primary pain: A systematic review
British Journal of Pharmacology, EarlyView.Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Pubescenol, a withanolide from Physalis pubescence
, 1984 A new withanolide, named pubescenol, and also physalin E and physalin E acetate have been isolated from Physalis pubescence. The structure of pubescenol is assigned as 4α,7α-dihydroxy-l-oxo-24α,25α-epoxy-2,3 ...
Dhaveji, K. +3 more
core +1 more source
MicrobiologyOpen, Volume 15, Issue 5, October 2026.The graphical abstract visually summarizes the study's key findings: it lists the major bacterial pathogens isolated from livestock wounds (such as S. aureus and E. coli) and the medicinal plants tested (Withania somnifera, Achyranthes aspera. It highlights the phytochemicals (alkaloids, flavonoids, etc.) present in the plant extracts and shows that ...
Safia Arbab +7 more
wiley +1 more source
A new withanolide from the roots of Withania somnifera
, 2004 2001-2003Phytochemical studies on the roots of Withania somnifera (Solanaceae) resulted in the isolation of a new withanolide glycoside, glucosomniferanolide, characterized as (20R, 22S)- 1-oxo-witha-2, 5, 24-trienolide-20-β-ol-20-D-glucopyranoside by
M. Ali +5 more
core +1 more source
Nano Select, Volume 7, Issue 10, October 2026.Surface‐modified niosomes are introduced as multifunctional nanoparticles for precision tumor treatment that combine hydrophilic and lipophilic drug encapsulation with ligand‐based targeting via antibodies, peptides, transferrin, and folic acid. This modification leads to increased tumor selectivity, facilitates cell entry, and enables enhanced ...
Narges Sahraei +3 more
wiley +1 more source
, 2014 Administration of withanolide A prior to and during hypoxic exposure decreases number of apoptotic cells in CA3 region of hippocampus while glutathione depletion using buthionine sulfoximine elevates hypoxic neuronal apoptosis.
Pradeep Kumar Naik (436805) +6 more
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Effect of heavy metals on germination, biochemical, antioxidant and withanolide content in Withania somnifera (L.) Dunal [PDF]
, 2023 Withania somnifera (L.) Dunal., commonly referred to as Ashwagandha, is a medicinal plant from the solanaceae family with a wide range of pharmacological properties. W.
Akshatha Banadka +3 more
core +1 more source
Pharmacological Effects of withanolides [PDF]
Open Access Journal of Complementary & Alternative Medicine, 2019 Withania somnifera (L.) Dunal (Family, Solanaceae) commonly known as Ashwgandha or winter cherry is one of the top medicinal herbs used in Ayurveda-the holistic system of Indian medicine.
openaire +1 more source