Results 51 to 60 of about 23,202,835 (216)

A New Rearranged Non-Aromatic Salpichrolide from Salpichroa Origanifolia

open access: yesMolecules, 2000
From the aerial parts of Salpichroa origanifolia a new withanolide in which the C-13 angular methyl has migrated to C-17, was isolated and characterized by spectroscopic methods.
M. C. Tettamanzi   +3 more
doaj   +1 more source

Sonication, Vacuum Infiltration and Thiol Compounds Enhance the Agrobacterium-Mediated Transformation Frequency of Withania somnifera (L.) Dunal. [PDF]

open access: yesPLoS ONE, 2015
In the present study, we have established a stable transformation protocol via Agrobacterium tumafacines for the pharmaceutically important Withania somnifera.
Ganeshan Sivanandhan   +5 more
doaj   +1 more source

Antitumor Potential of Withanolide Glycosides from Ashwagandha (Withania somnifera) on Apoptosis of Human Hepatocellular Carcinoma Cells and Tube Formation in Human Umbilical Vein Endothelial Cells

open access: yesAntioxidants, 2022
Hepatocellular carcinoma (HCC) is the fastest-growing tumor capable of spreading to other organs via blood vessels formed by endothelial cells. Apoptosis and angiogenesis-targeting therapies are attractive for cancer treatment. In this study, we aimed to
Dahae Lee   +8 more
doaj   +1 more source

Phytochemical Evaluation of Withanolide-A in Ashwagandha Roots from Different Climatic Regions of India

open access: yes, 2016
A b s t r a c t A r t i c l e I n f o Ashwagandha [Withania somnifera (L.) Dunal] is a highly valued medicinal plant in Ayurveda, used either singly or in combination with other herbs.
R. Shah   +3 more
semanticscholar   +1 more source

Chlorinated withanolides from Withania somnifera [PDF]

open access: yesPhytochemistry Letters, 2011
A chlorinated withanolide, 6α-chloro-5β,17α-dihydroxywithaferin A (1), and nine known withanolides, 6α-chloro-5β-hydroxywithaferin A (2), (22R)-5β-formyl-6β,27-dihydroxy-1-oxo-4-norwith-24-enolide, withaferin A, 2,3-dihydrowithaferin A, 3-methoxy-2,3-dihydrowithaferin A, 2,3-didehydrosomnifericin, withanone, withanoside IV and withanoside X, were ...
Tong, Xiaoqin   +2 more
openaire   +3 more sources

Safety of 8‐Week Administration With Ashwagandha (Withania somnifera) Root Extract in Adults With Stress and Anxiety: Findings From a Prospective, Randomized, Multi‐Center, Double‐Blinded, Placebo‐Controlled Study

open access: yesPhytotherapy Research, Volume 40, Issue 8, Page 5005-5015, August 2026.
ABSTRACT Ashwagandha ( Withania somnifera ) has been recognized for enhancing physical strength, mental well‐being, and overall vitality. Despite its long‐standing use across generations, some clinical reports have noted occasional adverse events. This study compared the safety and tolerability of Ashwagandha Root Extract (ARE) in healthy adults.
Ketan Pakhale   +4 more
wiley   +1 more source

Amelioration of bromobenzene hepatotoxicity by Withania somnifera pretreatment: Role of mitochondrial oxidative stress

open access: yesToxicology Reports, 2014
The present study investigated the possible protective role of Withania somnifera (Linn.) Dunal (Solanaceae) root powder against bromobenzene-induced oxidative damage in rat liver mitochondria.
Mahima Vedi   +2 more
doaj   +1 more source

Tackling Chronic Inflammation with Withanolide Phytochemicals—A Withaferin A Perspective

open access: yesAntioxidants, 2020
Chronic inflammatory diseases are considered to be one of the biggest threats to human health. Most prescribed pharmaceutical drugs aiming to treat these diseases are characterized by side-effects and negatively affect therapy adherence.
Emilie Logie, Wim Vanden Berghe
doaj   +1 more source

Laser‐Enabled Biotechnology Platforms for Climate‐Resilient Crop Production: Mechanistic Insights and Future Prospects

open access: yesFood and Energy Security, Volume 15, Issue 4, July/August 2026.
ABSTRACT Climate change poses a major threat to global food security through extreme weather events, expanding pathogen ranges, and increased agrochemical dependency. This review highlights the emerging role of laser biotechnology as a sustainable and precise strategy to enhance crop resilience and productivity under climate stress.
Temoor Ahmed   +9 more
wiley   +1 more source

Cytotoxic withanolide constituents of Physalis longifolia [PDF]

open access: yesPlanta Medica, 2011
Fourteen new withanolides, 1-14, named withalongolides A-N, respectively, were isolated from the aerial parts of Physalis longifolia together with eight known compounds (15-22). The structures of compounds 1-14 were elucidated through spectroscopic techniques and chemical methods.
Zhang, Huaping   +9 more
openaire   +3 more sources

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