Results 31 to 40 of about 114,627,962 (212)

Antifungal and antibacterial activities of crude withanolides extract from the roots of Withania somnifera (L.) Dunal (Ashwagandha)

open access: yesEnvironment Conservation Journal, 2010
Ashwagandha [Withania somnifera (L.) Dunal] is an important medicinal plant and its medicinal properties have been attributed to various classes of withanolide compounds.
H. Punetha, Shiv Om Singh, A. K. Gaur
doaj   +1 more source

Elucidating the active interaction mechanism of phytochemicals withanolide and withanoside derivatives with human serum albumin. [PDF]

open access: yesPLoS ONE, 2018
Withania somnifera (Ashwagandha) is an efficient medicinal plant known in Ayurveda and Chinese medicine since ancient times, whose extracts are consumed orally as food supplement or as a health tonic owing to its several restorative properties for ...
Shreya Dubey   +3 more
doaj   +1 more source

Pharmacological Effects of Withanolides [PDF]

open access: yesBiomedical Journal of Scientific & Technical Research, 2020
Withanolides is a class of active compounds widely found in Solanaceae plants. In traditional applications, it has a long history and a wide range of functions. With the progress of drug structure and pharmacological research, more and more reports point to its excellent anticancer effect.
openaire   +1 more source

Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine

open access: yesMolecules, 2009
Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and indigenous medicine for over 3,000 years.
Javier Palazón   +4 more
doaj   +1 more source

De novo assembly, functional annotation and comparative analysis of Withania somnifera leaf and root transcriptomes to identify putative genes involved in the withanolides biosynthesis. [PDF]

open access: yesPLoS ONE, 2013
Withania somnifera is one of the most valuable medicinal plants used in Ayurvedic and other indigenous medicine systems due to bioactive molecules known as withanolides.
Parul Gupta   +7 more
doaj   +1 more source

Withanolides from Withania coagulans

open access: yesPhytochemistry, 2003
Two withanolides, 20beta-hydroxy-1-oxo-(22R)-witha-2,5,24-trienolide (1) and withacoagulin (2), along with a known withanolide, 17beta-hydroxy-14alpha, 20alpha-epoxy-1-oxo-(22R)-witha-3,5,24-trienolide (3) were isolated from Withania coagulans. Their structures were elucidated with the help of different spectroscopic techniques.
Atta, ur-Rahman   +3 more
openaire   +5 more sources

Oxidative Stress and AKT-Associated Angiogenesis in a Zebrafish Model and Its Potential Application for Withanolides

open access: yesCells, 2022
Oxidative stress and the AKT serine/threonine kinase (AKT) signaling pathway are essential regulators in cellular migration, metastasis, and angiogenesis.
Jen-Yang Tang   +6 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review. [PDF]

open access: yesPhytother Res
ABSTRACT The preclinical evidence for the safety of ashwagandha ( Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports. Most studies and reviews conclude
Williamson EM, Brendler T.
europepmc   +2 more sources

Differential Gene Expression and Withanolides Biosynthesis During in vitro and ex vitro Growth of Withania somnifera (L.) Dunal

open access: yesFrontiers in Plant Science, 2022
Ashwagandha (Withania somnifera L. Dunal) is a medicinally important plant with withanolides as its major bioactive compounds, abundant in the roots and leaves.
Sachin Ashok Thorat   +9 more
doaj   +1 more source

Using silver nanoparticles to increase the accumulation of withanolide compounds in cultured callus of Withania somnifera L.

open access: yesمجلة مركز بحوث التقنيات الاحيائية
Background: Withania somnifera L. is a famous medicinal plant that has been utilized in Global folk medicine for a long time. The leaves and roots of the plant are rich in withanolide constituents, which are primarily responsible for their therapeutic ...
Ashwaq S. Abed   +2 more
doaj   +1 more source

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