Results 21 to 30 of about 23,202,835 (216)
Integrative Medicine Research, 2013 Background: Ashwagandharishtha is a liquid polyherbal formulation traditionally prepared by fermentation process using the flowers of Woodfordia fruticosa. It contains roots of Withania somnifera as a major crude drug.
Jagdish Manwar +4 more
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Biologia Plantarum, 2011 Squalene synthase (SS) dimerizes two molecules of farnesyl diphosphate to synthesize squalene, a shared precursor in steroid and triterpenoid biosynthesis in plants.
M. H. Mirjalili +4 more
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RNAi and Homologous Over-Expression Based Functional Approaches Reveal Triterpenoid Synthase Gene-Cycloartenol Synthase Is Involved in Downstream Withanolide Biosynthesis in Withania somnifera. [PDF]
PLoS ONE, 2016 Withania somnifera Dunal, is one of the most commonly used medicinal plant in Ayurvedic and indigenous medicine traditionally owing to its therapeutic potential, because of major chemical constituents, withanolides.
Smrati Mishra +6 more
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Elucidating the active interaction mechanism of phytochemicals withanolide and withanoside derivatives with human serum albumin. [PDF]
PLoS ONE, 2018 Withania somnifera (Ashwagandha) is an efficient medicinal plant known in Ayurveda and Chinese medicine since ancient times, whose extracts are consumed orally as food supplement or as a health tonic owing to its several restorative properties for ...
Shreya Dubey +3 more
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Induction of Quinone Reductase by Withanolides
Journal of Natural Products, 2002 Thirty-seven naturally occurring withanolides (1-37), previously isolated in our laboratories, were evaluated for their potential to induce quinone reductase with cultured murine hepatoma cells (Hepa 1c1c7). Spiranoid (29, 32) and 18-functionalized withanolides (2-5, 7-9, 24) were found to be potent inducers of the enzyme, while 5alpha-substituted ...
Misico, Rosana Isabel +12 more
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Environment Conservation Journal, 2010 Ashwagandha [Withania somnifera (L.) Dunal] is an important medicinal plant and its medicinal properties have been attributed to various classes of withanolide compounds.
H. Punetha, Shiv Om Singh, A. K. Gaur
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Cells, 2022 Oxidative stress and the AKT serine/threonine kinase (AKT) signaling pathway are essential regulators in cellular migration, metastasis, and angiogenesis.
Jen-Yang Tang +6 more
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Withanolides from Withania coagulans
Phytochemistry, 2003 Two withanolides, 20beta-hydroxy-1-oxo-(22R)-witha-2,5,24-trienolide (1) and withacoagulin (2), along with a known withanolide, 17beta-hydroxy-14alpha, 20alpha-epoxy-1-oxo-(22R)-witha-3,5,24-trienolide (3) were isolated from Withania coagulans. Their structures were elucidated with the help of different spectroscopic techniques.
Atta, ur-Rahman +3 more
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De novo assembly, functional annotation and comparative analysis of Withania somnifera leaf and root transcriptomes to identify putative genes involved in the withanolides biosynthesis. [PDF]
PLoS ONE, 2013 Withania somnifera is one of the most valuable medicinal plants used in Ayurvedic and other indigenous medicine systems due to bioactive molecules known as withanolides.
Parul Gupta +7 more
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Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine
Molecules, 2009 Withania somnifera, commonly known as Ashwagandha, is an important medicinal plant that has been used in Ayurvedic and indigenous medicine for over 3,000 years.
Javier Palazón +4 more
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