Results 71 to 80 of about 3,164 (224)

Cytotoxic withanolide constituents of Physalis longifolia [PDF]

Planta Medica, 2011
Fourteen new withanolides, 1-14, named withalongolides A-N, respectively, were isolated from the aerial parts of Physalis longifolia together with eight known compounds (15-22). The structures of compounds 1-14 were elucidated through spectroscopic techniques and chemical methods.
Zhang, Huaping, Samadi, Abbas K., Gallagher, Robert J., Araya, Juan Jose, Tong, Xiaoqin, Day, Victor W., Cohen, Mark S., Kindscher, Kelly, Gollapudi, Rao, Timmermann, Barbara N.   +9 more
openaire   +3 more sources

Laser‐Enabled Biotechnology Platforms for Climate‐Resilient Crop Production: Mechanistic Insights and Future Prospects

Food and Energy Security, Volume 15, Issue 4, July/August 2026.
ABSTRACT Climate change poses a major threat to global food security through extreme weather events, expanding pathogen ranges, and increased agrochemical dependency. This review highlights the emerging role of laser biotechnology as a sustainable and precise strategy to enhance crop resilience and productivity under climate stress.
Temoor Ahmed, Yumeng Lei, Muhammad Noman, Zhitao Li, Gabrijel Ondrasek, Muhammad Shafiq Shahid, Branko Petrinec, Xingjiang Qi, Bin Li, Yetong Qi   +9 more
wiley   +1 more source

A New Rearranged Non-Aromatic Salpichrolide from Salpichroa Origanifolia

Molecules, 2000
From the aerial parts of Salpichroa origanifolia a new withanolide in which the C-13 angular methyl has migrated to C-17, was isolated and characterized by spectroscopic methods.
M. C. Tettamanzi, J. R. De La Fuente, A. S. Veleiro, G. Burton   +3 more
doaj   +1 more source

Sonication, Vacuum Infiltration and Thiol Compounds Enhance the Agrobacterium-Mediated Transformation Frequency of Withania somnifera (L.) Dunal. [PDF]

PLoS ONE, 2015
In the present study, we have established a stable transformation protocol via Agrobacterium tumafacines for the pharmaceutically important Withania somnifera.
Ganeshan Sivanandhan, Gnajothi Kapil Dev, Jeevaraj Theboral, Natesan Selvaraj, Andy Ganapathi, Markandan Manickavasagam   +5 more
doaj   +1 more source

Antitumor Potential of Withanolide Glycosides from Ashwagandha (Withania somnifera) on Apoptosis of Human Hepatocellular Carcinoma Cells and Tube Formation in Human Umbilical Vein Endothelial Cells

Antioxidants, 2022
Hepatocellular carcinoma (HCC) is the fastest-growing tumor capable of spreading to other organs via blood vessels formed by endothelial cells. Apoptosis and angiogenesis-targeting therapies are attractive for cancer treatment. In this study, we aimed to
Dahae Lee, Jae Sik Yu, Ji Won Ha, Seoung Rak Lee, Bum Soo Lee, Jin-Chul Kim, Jung Kyu Kim, Ki Sung Kang, Ki Hyun Kim   +8 more
doaj   +1 more source

A New Antifeedant Withanolide from Jaborosa lanigera. [PDF]

, 2007
A new trechonolide-type withanolide, jaborosolactol, possessing a hemiketal ring system and a 5-membered lactol, has been isolated from the aerial parts of Jaborosa lanigera.
Biurrun, F.N., M. Cristina Tettamanzi, Fernando N. Biurrun, Cirigliano, A.M., Tettamanzi, M.C., Adriana M. Cirigliano   +5 more
core   +1 more source

DataSheet_1_Estimating the production of withaferin A and withanolide A in Withania somnifera (L.) dunal using aquaponics for sustainable development in hill agriculture.doc [PDF]

, 2023
IntroductionHumanity is suffering from huge and severe difficulties, including changes in climate, soil degradation, scarcity of water and the security of food and medicines, among others.
Kahkashan Perveen (11909840), Manali Singh, Mehrun Nisha Khanam, Santosh Chandra Bhatt (16910865), Anita Mishra, Mehrun Nisha Khanam (16910784), Deep Chandra Suyal (4541179), Santosh Chandra Bhatt, Anita Mishra (16910859), Nisha Dinkar (16910856), Nisha Dinkar, Manali Singh (15335929), Shivani Bhutani, Alanoud T. Alfagham, Deep Chandra Suyal, Shivani Bhutani (16910853), Kahkashan Perveen, Alanoud T. Alfagham (16910862)   +17 more
core   +1 more source

Ashwagandha Root Extract and Its Potential Modulation of CCN1‐Associated Pathways in Sensitive‐Skin Aging

Journal of Cosmetic Dermatology, Volume 25, Issue 7, July 2026.
ABSTRACT Background Cellular Communication Network Factor 1 (CCN1) has been identified as a key regulator of oxidative stress‐induced skin aging and sensitivity. Ashwagandha root extract (ARE) is a promising candidate for modulating CCN1‐associated pathways. Aims To investigate whether ARE can mitigate sensitive‐skin aging by modulating CCN1 expression
Liying Kang, Yanhong Liu, Yuchen Xin, Lin Geng, Shaochun Cai, Jianfang Luo, Shaojie Gu, Shuangyan Wang, Zhiting Zhang, Yan Huang, Guixuan Zhou, Li Ye, Dongcui Li, Naisheng Jiang   +13 more
wiley   +1 more source

Amelioration of bromobenzene hepatotoxicity by Withania somnifera pretreatment: Role of mitochondrial oxidative stress

Toxicology Reports, 2014
The present study investigated the possible protective role of Withania somnifera (Linn.) Dunal (Solanaceae) root powder against bromobenzene-induced oxidative damage in rat liver mitochondria.
Mahima Vedi, Mahaboobkhan Rasool, Evan Prince Sabina   +2 more
doaj   +1 more source

Tackling Chronic Inflammation with Withanolide Phytochemicals—A Withaferin A Perspective

Antioxidants, 2020
Chronic inflammatory diseases are considered to be one of the biggest threats to human health. Most prescribed pharmaceutical drugs aiming to treat these diseases are characterized by side-effects and negatively affect therapy adherence.
Emilie Logie, Wim Vanden Berghe
doaj   +1 more source