Results 171 to 180 of about 2,412 (209)

Withanolides of Acnistus breviflorus

Phytochemistry, 1981
The chemical examination of Acnistus breviflorus afforded nine withanolides, four of which are new and were established as 2,3,24,25-tetrahydro-27-desoxywithaferin A (4β-hydroxy-5β,6β-epoxy-1-oxo-22 R-withanolide), 2,3-dihydro-27-desoxywithaferin A (4β-hydroxy-5β,6β-epoxy-22 R-witha-24-enolide), 5,6-desoxywithaferin A (4β,27-dihydroxy-1-oxo-22 R-witha ...
S. Sarma Nittala, David Lavie
openaire   +1 more source

New withanolides from Mandragora officinarum: First report of withanolides from the Genus Mandragora

Fitoterapia, 2010
Two new withanolides named mandragorolide A (1) and mandragorolide B (2) were isolated from the MeOH extract of the whole plant of Mandragora officinarum of Jordanian origin, along with five known withanolides namely larnaxolide A (3), withanolide B (4), datura lactone 2 (5), withanicandrin (6) and salpichrolide C (7). Compound 3 has been reported only
Rami K, Suleiman, Musa Abu, Zarga, Salim S, Sabri   +2 more
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Withanolides of Datura metel

Phytochemistry, 1992
Abstract The leaves of Datura metel yielded three new withanolides in addition to lycium substance B, previously reported from other Datura species. The structures of the withanolides, clarified by comprehensive spectral analysis, showed features of typical daturalactones as well as of the withanolides of D. metel. p -Hydroxy cinnamic acid amide
Mohini Gupta, M. Manickam, Subhash C. Sinha, Anjana Sinha-Bagchi, Anil B. Ray   +4 more
openaire   +1 more source

Withanolides from Physalis hispida

Journal of Natural Products, 2014
Nine new withanolides (1-9), withahisolides A-I, were isolated along with nine known compounds (10-18) from the aerial parts of Physalis hispida. The structures of 1-9 were elucidated through a variety of spectroscopic techniques, while the structures of 1 and 2 were confirmed by X-ray crystallographic analysis. Compounds 1-3 are the first withanolides
Cong-Mei, Cao, Huaping, Zhang, Robert J, Gallagher, Victor W, Day, Kelly, Kindscher, Patrick, Grogan, Mark S, Cohen, Barbara N, Timmermann   +7 more
openaire   +2 more sources

Withanolides from Ajuga parviflora

Journal of Natural Products, 1999
Two new withanolides named ajugin A [14alpha,20, 28-trihydroxy-1-oxo-(20R,22R)-witha-3,5,24-trienolide] (1) and ajugin B [14alpha,20,27-trihydroxy-1-oxo-(20R,22R)-witha-5, 24-dienolide] (2) were isolated from the whole plant of Ajuga parviflora, and their structures were deduced by NMR and MS analyses.
, Khan, , Malik, , Ahmad, , Nawaz
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Antiproliferative Withanolides from Jaborosa Riojana

Fitoterapia
Six previously undescribed withanolides, of which three had a normal glycosylated skeleton (Jaborosalactones 49-51) and three had a sativolide skeleton (12-O-methyl jaborosalactone 52, jaborosalactone 53, and 12-O-methyl jaborosalactone 53), were isolated from the aerial parts of Jaborosa riojana.
Lobatto, Virginia Laura, Casero, Carina Noelia, González Bakker, Aday, Padrón, José M., Nicotra, Viviana Estela   +4 more
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Withanolide glycosides from dunalia australis*

Phytochemistry, 1992
Four new withanolide glycosides, (20R,22R)-O-(3)-[beta-D- xylopyranosyl(1----3), beta-D-xylopyranosyl(1----4)]-beta-D-glucopyranosyl-3 beta,20-dihydroxy-1 alpha-acetoxy-witha-5,24-dienolide, (20R,22R)-O-(3)-[beta-D-xylopyranosyl(1----3), beta-D-glucopyranosyl(1----4)]-beta-D-glucopyranosyl-3 beta,20-dihydroxy-1 alpha-acetoxy-witha-5,24-dienolide, (20R ...
M, Lischewski, N T, Hang, A, Porzel, G, Adam, G, Massiot, C, Lavaud   +5 more
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Withanolides from Salpichroa origanifolia

Journal of Natural Products, 2001
Five new withanolides, 5 alpha,6 alpha:22,26:24,25-triepoxy-16 alpha,26-dihydroxy-18(13-->17)-abeo-ergosta-2,13-dien-1-one (salpichrolide N, 1), 5 alpha,6 alpha:22,26:24,25-triepoxi-15 alpha,26-dihydroxyergosta-2,16-dien-1-one (salpichrolide L, 2), 5 alpha,6 alpha:22,26-diepoxi-24,25,26-trihydroxy-17(13-->18)-abeo-ergosta-2,13,15,17-tetraen-1-one ...
M C, Tettamanzi, A S, Veleiro, J R, de la Fuente, G, Burton   +3 more
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Withanolides: Promising candidates for cancer therapy

Phytotherapy Research
AbstractNatural products have played a significant role throughout history in the prevention and treatment of numerous diseases, particularly cancers. As a natural product primarily derived from various medicinal plants in the Withania genus, withanolides have been shown in several studies to exhibit potential activities in cancer treatment ...
Qiang Zhang, YongKang Yuan, Shijie Cao, Ning Kang, Feng Qiu   +4 more
openaire   +2 more sources

Molecular targets and mechanisms of anti-cancer effects of withanolides

Chemico-Biological Interactions, 2023
Zhiruo Zhang, Yueying Yang, Wenhui Liu   +2 more
exaly