Results 11 to 20 of about 237,377 (265)
Frontiers in Physiology, 2021 Exercise initiates systemic adaptation to promote health and prevent various lifestyle-related chronic diseases. Emerging evidence suggests that circulating exosomes mediate some of the beneficial effects of exercise via the transfer of microRNAs between
Kitti Garai +13 more
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eLife, 2021 Neuronal cell fate determinants establish the identities of neurons by controlling gene expression to regulate neuronal morphology and synaptic connectivity.
Mizuki Kurashina +5 more
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Crosstalk Between ER Stress, Unfolded Protein Response (UPR) and Wnt Signaling Pathway in Cancer [PDF]
Iranian Journal of Colorectal Research, 2020 : 1. Context Endoplasmic reticulum stress (ER stess) is associated with endoplasmic reticulum perturbation homeostasis. Prolonged ER stress conditions may induce cell death. Unfolded protein response (UPR) attempts to restore normal cell conditions.
Morvarid Siri +3 more
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The amyloid precursor protein is a conserved Wnt receptor
eLife, 2021 The Amyloid Precursor Protein (APP) and its homologues are transmembrane proteins required for various aspects of neuronal development and activity, whose molecular function is unknown.
Tengyuan Liu +11 more
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When Wnts antagonize Wnts [PDF]
The Journal of Cell Biology, 2003 Secreted Wnt ligands appear to activate a variety of signaling pathways. Two papers in this issue now present genetic evidence that “noncanonical” Wnt signaling inhibits the “canonical” Wnt/β-catenin pathway. Westfall et al. (2003a) show that zebrafish embryos lacking maternal Wnt-5 function are dorsalized due to ectopic activation of β-catenin ...
Weidinger, Gilbert, Moon, Randall T.
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Rab7 is required for mesoderm patterning and gastrulation in Xenopus
Biology Open, 2021 Early embryogenesis requires tightly controlled temporal and spatial coordination of cellular behavior and signaling. Modulations are achieved at multiple levels, from cellular transcription to tissue-scale behavior.
Jennifer Kreis +2 more
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Wnt3a and wnt5a as Potential Chondrogenic Stimulators for Nucleus Pulposus Cell Induction: A Comprehensive Review [PDF]
Neurospine, 2020 Low back pain remains a highly prevalent pathology engendering a tremendous socioeconomic burden. Low back pain is generally associated with intervertebral disc (IVD) degeneration, a process involving the deterioration of nucleus pulpous (NP) cells and ...
Tibo Nico Emmie Volleman +4 more
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Activation of the Wnt Pathway by Mycobacterium tuberculosis: A Wnt–Wnt Situation [PDF]
Frontiers in Immunology, 2017 Mycobacterium tuberculosis (M. tuberculosis), an intracellular pathogenic Gram-positive bacterium, is the cause of Tuberculosis, a major worldwide human infectious disease. The innate immune system is the first host defense against M. tuberculosis. The recognition of this pathogen is mediated by several classes of pattern recognition receptors (PRRs ...
Tomás Villaseñor +5 more
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EXCLI Journal : Experimental and Clinical Sciences, 2023 Circular RNAs (CircRNAs) are a class of regulatory RNA transcripts, which are ubiquitously expressed in eukaryotes. CircRNA dysregulation has been shown to disrupt the interaction of the Wnt/β-catenin pathway, which regulates several biological processes
Mina Alimohammadi +7 more
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Wnt and Wnt inhibitors in bone metastasis [PDF]
BoneKEy Reports, 2012 Bone metastasis is a clinically devastating development of progressive cancers including prostate carcinoma, breast carcinoma and multiple myeloma. Bone metastases are typically painful, lead to adverse skeletal-related events, such as fracture, and are highly resistant to therapy.
Joseph L, Sottnik +3 more
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