Results 41 to 50 of about 313,995 (297)

Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural Stem cell specification into oligodendrocytes and glutamatergic neurons [PDF]

, 2014
In the postnatal and adult central nervous system (CNS), the subventricular zone (SVZ) of the forebrain is the main source of neural stem cells (NSCs) that generate olfactory neurons and oligodendrocytes (OLs), the myelinating cells of the CNS.
Raineteau, Olivier, Fischer, Bruno,, Sommer, Lukas, Sommer, Lukas,, Draganova, Kalina,, Draganova, Kalina, Fischer, Bruno, Cantu, Claudio, Azim, Kasum,, Butt, Arthur, Raineteau, Olivier,, Butt, Arthur,, Azim, Kasum, Hurtado-Chong, Anahi,, Hurtado-Chong, Anahi, Cantù, Claudio,, Zemke, Martina, Zemke, Martina,, Butt A, Cantù C, Draganova K, Raineteau O, Sommer L, Fischer B, Zemke M, Hurtado-Chong A, Azim K   +26 more
core   +1 more source

The Oncogene AF1Q is Associated with WNT and STAT Signaling and Offers a Novel Independent Prognostic Marker in Patients with Resectable Esophageal Cancer

Cells, 2019
: AF1q impairs survival in hematologic and solid malignancies. AF1q expression is associated with tumor progression, migration, and chemoresistance, and acts as a transcriptional co-activator in WNT and STAT signaling.
Elisabeth S. Gruber, Georg Oberhuber, Peter Birner, Michaela Schlederer, Michael Kenn, Wolfgang Schreiner, Gerd Jomrich, Sebastian F. Schoppmann, Michael Gnant, William Tse, Lukas Kenner   +10 more
doaj   +1 more source

Wnt signalling in the development of axon, dendrites and synapses [PDF]

Open Biology, 2018
Wnts are a highly conserved family of secreted glycoproteins that play essential roles in the morphogenesis and body patterning during the development of metazoan species.
Chun-Wei He, Chien-Po Liao, Chun-Liang Pan   +2 more
doaj   +1 more source

Genetic dissection of differential signaling threshold requirements for the Wnt/β-catenin pathway in vivo [PDF]

, 2010
Contributions of null and hypomorphic alleles of Apc in mice produce both developmental and pathophysiological phenotypes. To ascribe the resulting genotype-to-phenotype relationship unambiguously to the Wnt/beta-catenin pathway, we challenged the allele
Newton, Ian P., Jarnicki, Andrew G., Nathke, Inke S.; id_orcid, Nathke, I., Samuel, M., Suzuki, Hiromu, Tosh, David, Abud, H E, Newton, IP, Huelsken, J, Stacker, SA, Samuel, M S, Buchert, M, Ernst, M., Stacker, S., Dimitris Athineos, Alan R Clarke, Newton Ian P., Helen E. Abud, Heath, JK, Abud Helen E., Clarke Alan R., Suzuki, H., Newton, I., Jarnicki, A.G., Meniel, VS, Michael Buchert, Ernst, Matthias, Sansom, Owen J., Sansom Owen J., Meniel, Valerie, Clarke, Alan R., Burke, Z D, Ian P Newton, Inke S Näthke, David Tosh, Näthke, I.S., Ian P. Newton, Sansom, O J, Burke, Z., Samuel Michael S., Samuel, M.S., Näthke Inke S., Inke S. Näthke, Jarnicki, A G, Abud, H.E., Tosh, D, Burke, ZD, Catherine E Winbanks, Samuel, Michael S., Heath Joan K., Andrew G Jarnicki, Nusse, R., Meniel, V.S., Abud, H., Samuel, MS, Joan K Heath, Winbanks, C E, Clarke, A R, Winbanks, C.E., Suzuki Hiromu, Winbanks Catherine E., Clarke, Alan Richard, Clarke, A.R., Joerg Huelsken, Stacker, Steven A., Helen E Abud, Alan R. Clarke, Buchert, M., Owen J. Sansom, Abud, HE, Joan K. Heath, Faux Maree C., Jarnicki, AG, Owen J Sansom, Athineos Dimitris, Suzuki, H, Faux, M., Winbanks, C., Matthias Ernst, Huelsken Joerg, Athineos, D, Sansom, O.J., Burke, Zoe D., Meniel Valerie S., Huelsken, J., Tosh David, Newton, I.P., Athineos, Dimitris, Ernst Matthias, Jarnicki Andrew G., Zoe D Burke, Stacker, S.A., Stacker, S A, Buchert, Michael, Abud, Helen E., Michael S. Samuel, Jarnicki, A., Steven A Stacker, Meniel, Valerie S., Faux, M C, Athineos, D., Meniel, V., Ernst, M, Michael S Samuel, Heath, Joan K., Nathke, I S, Sansom, OJ, Tosh, D., Valerie S. Meniel, Clarke, AR, Newton, I P, Näthke, Inke S., Meniel, V S, Valerie S Meniel, Buchert Michael, Newton, Ian P, Maree C Faux, Näthke, IS, Burke, Z.D., Heath, J., Maree C. Faux, Faux, Maree C., Winbanks, Catherine E., Heath, J K, Faux, M.C., Catherine E. Winbanks, Faux, MC, Sansom, O., Andrew G. Jarnicki, Steven A. Stacker, Hiromu Suzuki, Zoe D. Burke, Huelsken, Joerg, Heath, J.K., Stacker Steven A., Burke Zoe D., Winbanks, CE, Clarke, A.   +138 more
core   +2 more sources

MicroRNA-506 as a tumor suppressor in anaplastic thyroid carcinoma by regulation of WNT and NOTCH signaling pathways [PDF]

Iranian Journal of Basic Medical Sciences, 2023
Objective(s): Anaplastic thyroid carcinoma (ATC) is an aggressive thyroid tumor type that has a poor prognosis due to its high therapeutic resistance.
Zahra Nasrpour Navaei, Negin Taghehchian, Amir Sadra Zangouei, Mohammad reza Abbaszadegan, Meysam Moghbeli   +4 more
doaj   +1 more source

Cytoplasmic NOTCH and membrane-derived β-catenin link cell fate choice to epithelial-mesenchymal transition during myogenesis

eLife, 2016
How cells in the embryo coordinate epithelial plasticity with cell fate decision in a fast changing cellular environment is largely unknown. In chick embryos, skeletal muscle formation is initiated by migrating Delta1-expressing neural crest cells that ...
Daniel Sieiro, Anne C Rios, Claire E Hirst, Christophe Marcelle   +3 more
doaj   +1 more source

Bionanotechnological strategies for the synthesis of quercetin conjugates with selenium nanoparticles for their targeting of the Wnt/Ca2+signaling pathway [PDF]

Технологія виробництва і переробки продуктів тваринництва, 2023
One of the applications of nanotechnology is the synthesis of nanoparticles for targeted drug delivery and disease prevention. In the agricultural sector, nanotechnology holds great promise for improving animal health and productivity.
Bityutskyy V.S., Tsekhmistrenko S.I., Demchenko O.A., Tsekhmistrenko O.S., Melnychenko Yu.О., Kharchyshyn V.M.   +5 more
doaj   +1 more source

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression [PDF]

, 2012
Endothelial Wnt/β-catenin signaling is necessary for angiogenesis of the central nervous system and blood–brain barrier (BBB) differentiation, but its relevance for glioma vascularization is unknown. In this study, we show that doxycycline-dependent Wnt1
Devraj, Kavi, Nicole Ziegler, Fruttiger, Marcus, Rosario Heck, Sascha Seidel, Sonja Thom, Taketo, Makoto Mark, Kavi Devraj, Seidel, Sascha, Karl H. Plate, Liebner, Stefan, Reis, Marco, Bockamp, Ernesto, Heck, Rosario, Ernesto Bockamp, Marco Reis, Cathrin J. Czupalla, Makoto M. Taketo, Thom, Sonja, Zinke, Jenny, Plate, Karl, Macas, Jadranka, Jenny Zinke, Czupalla, Cathrin Jacqueline, Jadranka Macas, Stefan Liebner, Stefanie Dimmeler, Dimmeler, Stefanie, Ziegler, Nicole, Marcus Fruttiger   +29 more
core   +1 more source

FAM46C suppresses gastric cancer by inhibition of Wnt/β-catenin

Frontiers in Bioscience-Landmark, 2020
Gastric cancer (GC) is the most common cancer with a poor prognosis and the third leading cause of cancer death in the world, for which no effective therapeutic target exists.
Jun Shi, Qiuwei Zhu, Jianbo Wu, Ping Zhu
doaj   +1 more source

Wnt signaling [PDF]

WormBook, 2005
The use of Wnt ligands for signaling between cells is a conserved feature of metazoan development. Activation of Wnt signal transduction pathways upon ligand binding can regulate diverse processes including cell proliferation, migration, polarity, differentiation and axon outgrowth.
openaire   +2 more sources