Results 31 to 40 of about 237,377 (265)
Wnt5A Signaling Blocks Progression of Experimental Visceral Leishmaniasis
Frontiers in Immunology, 2022 Visceral leishmaniasis, caused by L. donovani infection is fatal if left untreated. The intrinsic complexity of visceral leishmaniasis complicated further by the increasing emergence of drug resistant L.
Shreyasi Maity +5 more
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Winning WNT: Race to Wnt signaling inhibitors [PDF]
Proceedings of the National Academy of Sciences, 2011 More than a quarter of a century ago, a mammalian homolog of Drosophila wingless, int-1 (Wnt1), was identified as an oncogenic viral integration site in mouse breast cancer (1). A decade later, deregulation of canonical Wnt/β-catenin signaling through mutations in adenomatous polyposis coli (APC) was recognized to be an initiating event in colon ...
Kazuhide, Watanabe, Xing, Dai
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Wnt Signaling in Neural Crest Ontogenesis and Oncogenesis
Cells, 2019 Neural crest (NC) cells are a temporary population of multipotent stem cells that generate a diverse array of cell types, including craniofacial bone and cartilage, smooth muscle cells, melanocytes, and peripheral neurons and glia during embryonic ...
Yu Ji +4 more
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MicroRNA-506 as a tumor suppressor in anaplastic thyroid carcinoma by regulation of WNT and NOTCH signaling pathways [PDF]
Iranian Journal of Basic Medical Sciences, 2023 Objective(s): Anaplastic thyroid carcinoma (ATC) is an aggressive thyroid tumor type that has a poor prognosis due to its high therapeutic resistance.
Zahra Nasrpour Navaei +4 more
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Cells, 2019 : AF1q impairs survival in hematologic and solid malignancies. AF1q expression is associated with tumor progression, migration, and chemoresistance, and acts as a transcriptional co-activator in WNT and STAT signaling.
Elisabeth S. Gruber +10 more
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Wnt signalling in the development of axon, dendrites and synapses [PDF]
Open Biology, 2018 Wnts are a highly conserved family of secreted glycoproteins that play essential roles in the morphogenesis and body patterning during the development of metazoan species.
Chun-Wei He +2 more
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Bionanotechnological strategies for the synthesis of quercetin conjugates with selenium nanoparticles for their targeting of the Wnt/Ca2+signaling pathway [PDF]
Технологія виробництва і переробки продуктів тваринництва, 2023 One of the applications of nanotechnology is the synthesis of nanoparticles for targeted drug delivery and disease prevention. In the agricultural sector, nanotechnology holds great promise for improving animal health and productivity.
Bityutskyy V.S. +5 more
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eLife, 2016 How cells in the embryo coordinate epithelial plasticity with cell fate decision in a fast changing cellular environment is largely unknown. In chick embryos, skeletal muscle formation is initiated by migrating Delta1-expressing neural crest cells that ...
Daniel Sieiro +3 more
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WormBook, 2005 The use of Wnt ligands for signaling between cells is a conserved feature of metazoan development. Activation of Wnt signal transduction pathways upon ligand binding can regulate diverse processes including cell proliferation, migration, polarity, differentiation and axon outgrowth.
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FAM46C suppresses gastric cancer by inhibition of Wnt/β-catenin
Frontiers in Bioscience-Landmark, 2020 Gastric cancer (GC) is the most common cancer with a poor prognosis and the third leading cause of cancer death in the world, for which no effective therapeutic target exists.
Jun Shi, Qiuwei Zhu, Jianbo Wu, Ping Zhu
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