Results 251 to 260 of about 2,032,739 (298)

The Wnt signaling pathway in cancer [PDF]

open access: yesCritical Reviews in Oncology/Hematology, 2016
The Wnt signaling pathway is critically involved in both the development and homeostasis of tissues via regulation of their endogenous stem cells. Aberrant Wnt signaling has been described as a key player in the initiation of and/or maintenance and development of many cancers, via affecting the behavior of Cancer Stem Cells (CSCs).
Yong-Mi Kim, Michael Kahn
exaly   +3 more sources

Wnt signaling pathway in cancer immunotherapy

Cancer Letters, 2022
Wnt/β-catenin signaling is a highly conserved pathway that regulates cell proliferation, differentiation, apoptosis, stem cell self-renewal, tissue homeostasis, and wound healing. Dysregulation of the Wnt pathway is intricately involved in almost all stages of tumorigenesis in various cancers. Through direct and/or indirect effects on effector T cells,
Yang Zhou, Haichang Luo
exaly   +3 more sources

Wnt signaling pathway: A comprehensive review

Cell Biology International, 2022
AbstractWnt signaling is an evolutionary cell‐to‐cell coordination mechanism and it is highly critical for a variety of physiological processes of an organism's body, including stem cell regeneration, proliferation, division, migration, polarity of a cell, determining fate of the cell and specification of neural crest, neural symmetry and morphogenesis.
Rabia Hayat   +2 more
openaire   +2 more sources

Wnt signalling: pathway or network?

Current Opinion in Genetics & Development, 1999
Members of the Wnt family of secreted glycoproteins participate in many signalling events during development. Recent findings suggest that Wnt signals can sometimes play a permissive role during cell-fate assignment. Wnt proteins have been shown to interact with a number of extracellular and cell-surface proteins, whereas many intracellular components ...
Arias, Alfonso Martinez   +2 more
openaire   +2 more sources

Wnt Signaling Pathway in Schizophrenia

CNS & Neurological Disorders - Drug Targets, 2014
The Wnt signaling pathway is one of the crucial signaling pathways that regulate many aspects of central nervous system. In this review, we tempt to depict an overall picture of the Wnt signaling with its multitude of roles in schizophrenia. If the Wnt signaling pathway plays a crucial role in the pathogenesis of schizophrenia as we suggest, a better ...
Yanmin, Peng, Yifeng, Xu, Donghong, Cui
openaire   +2 more sources

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