Induction of zinc conjugated with Doxorubicin for the prevention of aggregating β-catenin in the Wnt signaling pathway investigated through computational approaches. [PDF]
Rajagopal G +7 more
europepmc +1 more source
Comparison of the Anticancer Effects of a Complementary Peptide for Dickkopf WNT Signaling Pathway Inhibitor 3 (DKK3) With Conventional Anticancer Drugs in the Treatment of Oral Squamous Cell Carcinoma: A Pilot Study. [PDF]
Katase N +3 more
europepmc +1 more source
Schistosoma sex-biased microRNAs regulate ovarian development and egg production by targeting Wnt signaling pathway. [PDF]
Du P +7 more
europepmc +1 more source
EXPRESSION OF CONCERN: Subtype-Specific Alterations of the Wnt Signaling Pathway in Breast Cancer: Clinical and Prognostic Significance. [PDF]
europepmc +1 more source
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Wnt signaling pathway in cancer immunotherapy
Cancer Letters, 2022Wnt/β-catenin signaling is a highly conserved pathway that regulates cell proliferation, differentiation, apoptosis, stem cell self-renewal, tissue homeostasis, and wound healing. Dysregulation of the Wnt pathway is intricately involved in almost all stages of tumorigenesis in various cancers. Through direct and/or indirect effects on effector T cells,
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Wnt signaling pathway: A comprehensive review
Cell Biology International, 2022AbstractWnt signaling is an evolutionary cell‐to‐cell coordination mechanism and it is highly critical for a variety of physiological processes of an organism's body, including stem cell regeneration, proliferation, division, migration, polarity of a cell, determining fate of the cell and specification of neural crest, neural symmetry and morphogenesis.
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Wnt signalling: pathway or network?
Current Opinion in Genetics & Development, 1999Members of the Wnt family of secreted glycoproteins participate in many signalling events during development. Recent findings suggest that Wnt signals can sometimes play a permissive role during cell-fate assignment. Wnt proteins have been shown to interact with a number of extracellular and cell-surface proteins, whereas many intracellular components ...
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Wnt Signaling Pathway in Schizophrenia
CNS & Neurological Disorders - Drug Targets, 2014The Wnt signaling pathway is one of the crucial signaling pathways that regulate many aspects of central nervous system. In this review, we tempt to depict an overall picture of the Wnt signaling with its multitude of roles in schizophrenia. If the Wnt signaling pathway plays a crucial role in the pathogenesis of schizophrenia as we suggest, a better ...
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