Results 51 to 60 of about 169,270 (280)
Data describing the solution structure of the WW3* domain from human Nedd4-1
The third WW domain (WW3*) of human Nedd4-1 (Neuronal precursor cell expressed developmentally down-regulated gene 4-1) interacts with the poly-proline (PY) motifs of the human epithelial Na+ channel (hENaC) subunits at micromolar affinity.
Vineet Panwalkar +5 more
doaj +1 more source
A multi-exon deletion within WWOX is associated with a 46,XY disorder of sex development [PDF]
Disorders of sex development (DSD) are congenital conditions where chromosomal, gonad or genital development is atypical. In a significant proportion of 46,XY DSD cases it is not possible to identify a causative mutation, making genetic counseling ...
AJ Notini +32 more
core +1 more source
Dynameomics: protein dynamics and unfolding across fold space
All currently known structures of proteins together define ‘protein fold space’. To increase the general understanding of protein dynamics and protein folding, we selected a set of 807 proteins and protein domains that represent 95% of the currently ...
Jonsson Amanda L. +3 more
doaj +1 more source
Modeling conformational ensembles of slow functional motions in Pin1-WW.
Protein-protein interactions are often mediated by flexible loops that experience conformational dynamics on the microsecond to millisecond time scales. NMR relaxation studies can map these dynamics.
Faruck Morcos +10 more
doaj +1 more source
Gauge invariant formulation of strong WW scattering
Models of strong $WW$ scattering in the $s$-wave can be represented in a gauge invariant fashion by defining an effective scalar propagator that represents the strong scattering dynamics.
Azuelos +26 more
core +1 more source
Density of Eigenvalues of Random Normal Matrices with an Arbitrary Potential, and of Generalized Normal Matrices [PDF]
Following the works by Wiegmann-Zabrodin, Elbau-Felder, Hedenmalm-Makarov, and others, we consider the normal matrix model with an arbitrary potential function, and explain how the problem of finding the support domain for the asymptotic eigenvalue ...
Etingof, Pavel, Ma, Xiaoguang
core +8 more sources
WWC1 (WW and C2 domain containing 1) [PDF]
Review on WWC1, with data on DNA/RNA, on the protein encoded and where the gene is implicated.
Zhang, L, Dong, J
openaire +2 more sources
The WWOX gene has a WW domain containing oxidoreductase, which is located at the common fragile site FRA16D at chromosome 16q23. WWOX is a tumor suppressor gene that has been associated with several types of cancer such as hepatic, breast, lung, prostate,
Ehaideb Salleh N. +4 more
doaj +1 more source
Substrate proteolysis is inhibited by dominant-negative Nedd4 and Rsp5 mutants harboring alterations in WW domain 1 [PDF]
Mammalian Nedd4 and its budding yeast orthologue Rsp5 are members of a large family of HECT-domain-containing ubiquitin ligases. Besides possessing a Ca2+/lipid-binding domain, both ligases have multiple protein-interacting modules termed WW domains. The
Haines, D., Kumar, S., Shcherbik, N.
core
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source

