Results 51 to 60 of about 1,533 (168)

Cells of Escherichia coli Contain a Protein-Tyrosine Kinase, Wzc, and a Phosphotyrosine-Protein Phosphatase, Wzb [PDF]

open access: yesJournal of Bacteriology, 1999
ABSTRACT Two proteins of Escherichia coli , termed Wzc and Wzb, were analyzed for their capacity to participate in the reversible phosphorylation of proteins on tyrosine. First, Wzc was overproduced from its specific gene and purified to homogeneity by affinity chromatography.
Vincent, C.   +5 more
openaire   +3 more sources

Different gut microbiome dysbioses impact the evolutionary fate of hypervirulent Klebsiella pneumoniae

open access: yesiMeta, EarlyView.
Transient exposure to ampicillin results in restructuring of microbiota to favor oxygen‐tolerant bacteria, whereas osmotic laxative perturbation preserves Bacteriodota. Ampicillin‐ but not laxative‐exposed environment favors establishment of rmpA phase variants that lost hypermucoviscosity but short‐chain fatty acids present in the laxative‐exposed gut
Carey Lim   +9 more
wiley   +1 more source

Diversity of capsular polysaccharide gene clusters in Kpc-producing Klebsiella pneumoniae clinical isolates of sequence type 258 involved in the Italian epidemic. [PDF]

open access: yesPLoS ONE, 2014
Strains of Klebsiella pneumoniae producing KPC-type beta-lactamases (KPC-Kp) are broadly disseminating worldwide and constitute a major healthcare threat given their extensively drug resistant phenotypes and ability to rapidly disseminate in healthcare ...
Marco Maria D'Andrea   +7 more
doaj   +1 more source

Interactive segmentation of membrane and membrane‐mimic densities in cryo‐EM maps

open access: yesActa Crystallographica Section D, Volume 82, Issue 8, Page 848-861, August 2026.
SURFER performs automated segmentation of contextual membrane and membrane‐mimic density in cryo‐EM maps to enable robust separation of macromolecular signal from surrounding detergent or lipid–membrane features. It is conveniently distributed as a plugin for UCSF ChimeraX, allowing interactive application within standard map‐visualization workflows ...
Alok Bharadwaj   +2 more
wiley   +1 more source

The MIREN Road Survey Database: Standardized Vegetation Sampling to Advance Our Understanding of Biodiversity Responses in Mountain Systems Across the Globe

open access: yesGlobal Ecology and Biogeography, Volume 35, Issue 8, August 2026.
ABSTRACT Motivation The database initiated by the Mountain Invasion Research Network (MIREN) is one of the few globally implemented standardized vegetation surveys in mountains. The focus is on collecting plant species occurrences at 5‐year intervals along and adjacent to mountain roads spanning elevational gradients, with the goal of providing ...
Sylvia Haider   +68 more
wiley   +1 more source

Nuclear dysfunction in aging and neurodegeneration

open access: yesAlzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract Neurodegenerative diseases are characterized by a loss of neuronal function and structure, often in a region‐specific manner. Multiple factors contribute to neuronal dysfunction and death, including pathogenic protein buildup, protein mislocalization, and inflammation. Despite extensive research, the common mechanisms driving neurodegeneration
Abbigael Aday   +7 more
wiley   +1 more source

Comparative Proteomic Profiling of Clinical Klebsiella pneumoniae Strains and the Corresponding Outer Membrane Vesicles

open access: yesJournal of Extracellular Biology, Volume 5, Issue 4, April 2026.
ABSTRACT Klebsiella pneumoniae (K. pneumoniae) has become a global threat due to the convergence of carbapenem resistance and hypervirulence. Outer membrane vesicles (OMVs) play important roles in bacterial pathogenicity, yet their functional coordination with strains remains unclear.
Zongping Li   +12 more
wiley   +1 more source

A. baumannii Wzc autokinase determines capsular exopolysaccharide polymer length.

open access: yes, 2015
A-D. Spontaneous point mutations in autokinase domain result in misregulation of capsular exopolysaccharide production. A. Colony morphology on LB plates. Scale bar: 1cm. B. Capsules were analyzed by India ink staining (Scale bar: 10μm).
Ralph R. Isberg (145637)   +1 more
core   +1 more source

Metabolic Alterations in Macrophage Subtypes Propel Immune and Stromal Remodeling in Neurofibroma's Malignant Progression

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Illustration of the microenvironment factors driving malignant progression in MPNSTs. ABSTRACT Neurofibromatosis type 1 (NF1) is characterized by the development of benign plexiform neurofibromas (PNFs). In 10%–15% of patients, these tumors undergo malignant transformation into aggressive malignant peripheral nerve sheath tumors (MPNSTs).
Ling‐Ling Ge   +11 more
wiley   +1 more source

Engineering Fully‐Exposed Ir Clusters on Tin Oxide Surface for Highly Sensitive and Stable H2 Sensing

open access: yesRare Metals, Volume 45, Issue 1, January 2026.
ABSTRACT Metal oxide semiconductor‐supported noble metal nanoparticles are common sensing materials for gas sensors. However, the large size and their tendency to migrate at high temperatures often lead to inferior sensing sensitivity and stability. Herein, a salt‐assistant strategy is developed to prepare fully‐exposed Ir clusters on SnO2 nanorods ...
Yi Jiang   +7 more
wiley   +1 more source

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