Results 31 to 40 of about 1,511 (146)

Epidemiological characteristics of multidrug-resistant Acinetobacter baumannii ST369 in Anhui, China

mSystems, 2023
Acinetobacter baumannii is of growing concern for global health owing to its ability to evade the immune system and develop resistance to antibiotics. We analyzed A.
Yi Huang, Md Roushan Ali, Wei Li, Wanying Wang, Yuanyuan Dai, Huaiwei Lu, Zhien He, Yujie Li, Baolin Sun   +8 more
doaj   +1 more source

Tyrosine phosphorylation controlled poly(A) polymerase I activity regulates general stress response in bacteria

Life Science Alliance, 2023
We show a tyrosine phosphorylation–controlled poly(A) polymerase I polyadenylation activity regulated stress response mechanism in bacteria that is distinct and operates downstream of the primary stress regulator RpoS.
Nimmy Francis, Malaya R Behera, Kathiresan Natarajan, Rakesh S Laishram   +3 more
doaj   +1 more source

Genomic and Phenotypic Evolution of Tigecycline-Resistant Acinetobacter baumannii in Critically Ill Patients

Microbiology Spectrum, 2022
Acinetobacter baumannii is an important opportunistic pathogen of nosocomial infections. A. baumannii presently exhibits increasing antibiotic resistance, which poses great challenges to public health. The occurrence of tigecycline-resistant A. baumannii
Jiangang Zhang, Jinru Xie, Henan Li, Zhiren Wang, Yuyao Yin, Shuyi Wang, Hongbin Chen, Qi Wang, Hui Wang   +8 more
doaj   +1 more source

The Escherichia coli phosphotyrosine proteome relates to core pathways and virulence. [PDF]

PLoS Pathogens, 2013
While phosphotyrosine modification is an established regulatory mechanism in eukaryotes, it is less well characterized in bacteria due to low prevalence. To gain insight into the extent and biological importance of tyrosine phosphorylation in Escherichia
Anne-Marie Hansen, Raghothama Chaerkady, Jyoti Sharma, J Javier Díaz-Mejía, Nidhi Tyagi, Santosh Renuse, Harrys K C Jacob, Sneha M Pinto, Nandini A Sahasrabuddhe, Min-Sik Kim, Bernard Delanghe, Narayanaswamy Srinivasan, Andrew Emili, James B Kaper, Akhilesh Pandey   +14 more
doaj   +1 more source

Clinical Evaluation of the Efficacy and Safety of Co-Administration of Wuzhi Capsule and Tacrolimus in Adult Chinese Patients with Myasthenia Gravis

Neuropsychiatric Disease and Treatment, 2021
Yuyao Peng, Fei Jiang, Ran Zhou, Wanlin Jin, Yi Li, Weiwei Duan, Liqun Xu, Huan Yang Department of Neurology, Xiangya Hospital, Central South University, Changsha, 410008, People’s Republic of ChinaCorrespondence: Liqun Xu; Huan YangDepartment of ...
Peng Y, Jiang F, Zhou R, Jin W, Li Y, Duan W, Xu L, Yang H   +7 more
doaj  

Investigation of the Impact of CYP3A5 Polymorphism on Drug–Drug Interaction between Tacrolimus and Schisantherin A/Schisandrin A Based on Physiologically-Based Pharmacokinetic Modeling

Pharmaceuticals, 2021
Wuzhi capsule (WZC) is commonly prescribed with tacrolimus in China to ease drug-induced hepatotoxicity. Two abundant active ingredients, schisantherin A (STA) and schisandrin A (SIA) are known to inhibit CYP3A enzymes and increase tacrolimus’s exposure.
Qingfeng He, Fengjiao Bu, Hongyan Zhang, Qizhen Wang, Zhijia Tang, Jing Yuan, Hai-Shu Lin, Xiaoqiang Xiang   +7 more
doaj   +1 more source

wzc sequence alignment across 12 capsular types.

, 2013
wzc sequences of 17 strains (NTUH-K2044, DTS, Chedid, NTUH-K9534, Kauffmann E5051, VGH404, VGH484, NK245, VGH916, NTUH-KP13, NK8, 889/50, MGH 78578, NTUH-KP35, A1142, VGH698 and A1517) representing 12 capsular types (K1, K2, K5, K9, K10, K14, K20, K52 ...
Tzu-Lung Lin (123673), Meng-Chuan Wu (180675), Jin-Town Wang (123680), Yi-Jiun Pan (180680), Yen-Hua Chen (494789), Pei-Fang Hsieh (180668), Chun-Ru Hsu (440956)   +6 more
core   +1 more source

Wza gene knockout decreases Acinetobacter baumannii virulence and affects Wzy-dependent capsular polysaccharide synthesis

Virulence, 2020
To investigate the virulence of capsular polysaccharide export protein (Wza) in carbapenem-resistant Acinetobacter baumannii and its effect on capsule formation.
Tianshui Niu, Lihua Guo, Qixia Luo, Kai Zhou, Wei Yu, Yunbo Chen, Chen Huang, Yonghong Xiao   +7 more
doaj   +1 more source

Structural comparison CapAB/Wzc. A

, 2013
– Global superimposition. The structure of CapA1B1 (in cyan) has been superimposed with the CapA1B2 phosphorylated monomer (in blue) (PDB ID 3BFV) as well as with a subunit of the non-phosphorylated Wzc(K540M) octamer (in magenta) (PDB ID 3LA6).
Magali Aumont-Nicaise (161478), Sylvie Nessler (271816), Virginie Gueguen-Chaignon (271798), Aurore Fleurie (469897), Julien Nourikyan (469896), Solange Moréra (5656639), Vanesa Olivares-Illana (35761), Emmanuelle Béchet (5656636), Jakub Gruszczyk (469895), Céline Freton (469898), Christophe Grangeasse (271397)   +10 more
core   +1 more source

DataSheet2_The pharmacokinetic study of tacrolimus and Wuzhi capsule in Chinese liver transplant patients.docx

, 2022
Objectives: Wuzhi Capsule (WZC) is often administrated with tacrolimus in liver transplant patients to reduce the toxicity of tacrolimus and relieve the financial burden of patients. We aimed to investigate the interaction between Wuzhi Capsule (WZC) and
Binguo Liu (13797355), Fei Teng (201085), Rongrong Bian (13797352), Jingwen Zhai (11369733), Hua Wei (60877), Jiani Chen (4761183), Jinlong Qu (6893951), Wenyuan Guo (5941574)   +7 more
core   +1 more source