Klebsiella pneumoniae is a leading cause of nosocomial infections, including pneumonia, bacteremia, and urinary tract infections. Treatment options are increasingly restricted by the high prevalence of resistance to frontline antibiotics, including ...
Olga Ovchinnikova +2 more
exaly +6 more sources
The role of the tyrosine kinase Wzc (Sll0923) and the phosphatase Wzb (Slr0328) in the production of extracellular polymeric substances (EPS) by Synechocystis PCC 6803 [PDF]
Many cyanobacteria produce extracellular polymeric substances (EPS) mainly composed of heteropolysaccharides with unique characteristics that make them suitable for biotechnological applications.
José P Leite +2 more
exaly +14 more sources
Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent <i>Klebsiella pneumoniae</i> in Swine: Genomic Insights and Functional Validation. [PDF]
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Chen Z +15 more
europepmc +2 more sources
The effects of 5 MeV Au3+ ions irradiation damage on surface blistering and deuterium (D) retention behaviors in tungsten (W) and W-0.5 wt% ZrC alloy (WZC) have been studied after exposure to a low energy (38 eV D-1) D plasma under the fluence of ∼1 ...
Xue-Xi Zhang +5 more
doaj +2 more sources
Hypermucoviscosity in Klebsiella pneumoniae: manifestation, regulation, and roles in pathogenesis [PDF]
In recent years, Klebsiella pneumoniae (Kpn) has evolved into a global public health threat. Convergent Kpn lineages that are both hypervirulent and multidrug-resistant have emerged and can cause community-acquired, drug-resistant infections, with ...
Tamal Dey, Manoharan Shankar
doaj +2 more sources
Tyrosine phosphorylation of protein kinase Wzc from Escherichia coli K12 occurs through a two-step process. [PDF]
International audienceIn bacteria, several proteins have been shown to autophosphorylate on tyrosine residues, but little is known on the molecular mechanism of this modification.
Grangeasse, C., Doublet, P., Cozzone, Aj
core +6 more sources
Type C behavior pattern. Study of developmental and psychosocial factors and counterparts of WZC [PDF]
Type C personality – type C pattern – was introduced by T. Morris and S. Greer to define cancer personality, that is cancer-prone risk factor. It describes personality – behaviour pattern as negative emotionality: denial, non-expression of negative ...
Kubacka-Jasiecka, Dorota
core +5 more sources
In vivo evolution to hypermucoviscosity and ceftazidime/avibactam resistance in a liver abscess caused by Klebsiella pneumoniae sequence type 512 [PDF]
Carbapenemase-producing Klebsiella pneumoniae represents a major public health issue globally. Isolates with resistance to the newest drugs, like ceftazidime/avibactam (CZA), are increasingly reported.
Valerio Capitani +12 more
doaj +2 more sources
Ceftazidime-avibactam resistance in KPC-producing Klebsiella pneumoniae accompanied hypermucoviscosity acquisition [PDF]
Background Antimicrobial resistance and bacterial hypermucoviscosity, associated with escalating production of capsules, constitute major challenges for the clinical management of Klebsiella pneumoniae (K. pneumoniae) infections.
Yingyi Guo +14 more
doaj +2 more sources
A phage cocktail with bactericidal and virulence-attenuating effects against dairy-associated hypervirulent Klebsiella pneumoniae [PDF]
Klebsiella pneumoniae is an opportunistic pathogen associated with bovine mastitis and dairy contamination, threatening animal health and food safety. This study addresses iuc3-positive, multidrug-resistant, hypervirulent K.
Xing Ji +6 more
doaj +2 more sources

