Results 131 to 140 of about 58,088 (256)

Northeast China Traditional Kimchi (Paocai) Probiotic Resources Metabolized Uric Acid and Relieved Hyperuricemia in Mice

eFood, Volume 7, Issue 4, August 2026.
Traditional fermented Kimchi “paocai”, commonly consumed in Northeast China, was screened for probiotic resources capable of degrading uric acid in vitro and alleviating hyperuricemia in a mouse model. Abstract Current pharmacological therapies for hyperuricemia (HUA), though effective, pose safety concerns, including allopurinol‐induced severe dermal ...
Aman Khan, Xiaoyu Wang, Binyu Cui, Xiaoqian Zhou, Yingying Lu, Lifang Ma, Qizhuang Li, Dechun Yin, Weidong Wang   +8 more
wiley   +1 more source

Therapeutic Strategies for Hyperuricemia: From Small-Molecule Inhibitors to RNA Therapeutics. [PDF]

ACS Pharmacol Transl Sci
Yu X, Zhang M, Huang Y.
europepmc   +1 more source

Dioxomolybdenum(VI) Complexes Supported by Fluxional Bis(amide)‐Functionalized Aminophenolate Ligands

European Journal of Inorganic Chemistry, Volume 29, Issue 22, 1 August 2026.
New bis(amide) aminophenolate ligands form dioxomolybdenum(vi) and dioxotungsten(vi) complexes showing solvent‐dependent nuclearity. Whilst monomeric complexes featuring methoxide ligands are obtained in methanol, water triggers formation of μ‐oxo‐bridged dimers via oxo exchange, verified by 18O labelling.
Pasi Vikberg, Anssi Peuronen, Manu Lahtinen, Ari Lehtonen   +3 more
wiley   +1 more source

Study on Early Pregnancy Diagnosis of Sows Based on Body Fluid Metabolite Detection Combined with Machine Learning Models. [PDF]

Vet Sci
Feng Y, Gao R, Yang W, Lu H, Sun W, Zhang Y, Ren Y, Gao L, Li M, Li Q, Pu G, Zhang Y, Ai Z, Yan K, Huang T.   +14 more
europepmc   +1 more source

The Therapeutic Potential of H2S‐Releasing Platforms in Cardiovascular Applications

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 8, August 2026.
The Therapeutic Potential of H2S‐Releasing Platforms. ABSTRACT Once known as a toxic gas, hydrogen sulfide (H2S) is now making its way into many therapeutic applications. Similar to its other fellow endogenous gasotransmitters, nitric oxide and carbon monoxide, H2S is a small gas with a short half‐life, making it extremely capable of penetrating ...
Tia N. Shorter, Elizabeth J. Brisbois
wiley   +1 more source

Rationale for the Use of 8-Aminoguanine for the Management of Cystitis. [PDF]

Int J Urol
Birder LA, Stern JNH, Moldwin R, Jackson EK.   +3 more
europepmc   +1 more source

Zingerone Alleviates Acetaminophen‐Induced Liver Damage by Regulating Oxidative Stress, Inflammation, Apoptosis, Endoplasmic Reticulum Stress, and Autophagy

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Mechanism of action of zingerone on acetaminophen‐induced liver damage. ABSTRACT The aim of this study is to investigate the protective effect of zingerone (ZNG), an antioxidant agent, against acetaminophen (APAP)‐induced liver damage, which is used as an analgesic and antipyretic. For this purpose, twenty‐eight male rats were divided into four groups:
Serpil Aygörmez, Mustafa Makav, Sevda Eliş Yıldız, Elif Dalkılınç, Mushap Kuru, Şaban Maraşlı   +5 more
wiley   +1 more source

A universal fluorescent sensing platform based on "signal switching induced by enzyme catalyzed substrate hydrolysis" for high-throughput discovery of xanthine oxidase inhibitors from traditional Chinese medicine. [PDF]

Front Pharmacol
Liu G, Sun K, Lai S, Liu X, Ge Y, Wang P, Wang B, Li Y, Yu XA.   +8 more
europepmc   +1 more source

ON THE MECHANISM OF INHIBITION OF XANTHINE OXIDASE BY THE SUBSTRATE XANTHINE

Journal of Biological Chemistry, 1955
openaire   +2 more sources

Isobavachin Attenuates Renal and Cardiac Injury in Chronic Hyperuricemia via Modulation of NF‐κB and NLRP3 Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Isobavachin alleviates HUA‐induced oxidative stress, inflammation, and fibrosis in the kidney and heart, potentially through its dual role in promoting UA excretion and inhibiting NF‐κB signaling and NLRP3 inflammasome activation. ABSTRACT Hyperuricaemia (HUA) is a recognized risk factor for cardiovascular and renal diseases.
Yongmei Li, Yuexin Xu, Wenjie Ye, Zeqi Yu, Zhenkun Wu, Xinyi Liu, Xuhong Huang, Jianxin Pang, Zean Zhao, Ting Wu   +9 more
wiley   +1 more source