Ameliorating Acute Kidney Injury Induced by Ischemia-Reperfusion by Targeting Purine Metabolism. [PDF]
Zhao L, Zhang T, Zhou X.
europepmc +1 more source
Distinct classes of gut bacterial molybdenum-dependent enzymes produce urolithins. [PDF]
Bae M +7 more
europepmc +1 more source
Recherche de la xanthine oxydase appliquée à la mise en évidence du lait de vache ajouté au lait de chèvre. Mise au point d'un microtest [PDF]
D Monget +3 more
openalex +1 more source
Untersuchungen zum Ursprung der Substratspezifität von Enzymen der Amidohydrolase‐Superfamilie
Umfassende Analysen zweier Enzymklassen aus der Amidohydrolase‐Superfamilie (AHS) ergaben, dass die Katalyse über eine 1,4‐ bzw. 1,6‐nukleophile konjugierte Addition abläuft und diese Eigenschaft die Substratspezifität bestimmt. Obwohl alle Substrate und Produkte vollständig achiral sind, führt dieser mechanistische Unterschied zu einer invertierten ...
Lukas Drexler +3 more
wiley +1 more source
Xanthine Oxidase-Dependent Activation of NLPR3 Inflammasome in Epithelial Cells Sustains Inflammation in Inflammatory Bowel Disease. [PDF]
Di Petrillo A +15 more
europepmc +1 more source
Evaluation of the role of xanthine oxidase in myocardial reperfusion injury.
S. L. Thompson-Gorman, Jay L. Zweíer
openalex +1 more source
On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily
Comprehensive analyses of two enzyme classes from the amidohydrolase superfamily (AHS) revealed that catalysis proceeds either via 1,4 or 1,6 nucleophilic conjugate addition and that this property defines substrate specificity. Moreover, although all substrates and products are entirely achiral, this mechanistic difference results in an inverted ...
Lukas Drexler +3 more
wiley +1 more source
Unveiling of phosphodiesterase-5 hot residues binding to xanthine derivatives for erectile dysfunction therapy: A computational drug repurposing approach. [PDF]
Elzupir AO, Almahmoud SAJ.
europepmc +1 more source
Interactions between serum uric acid and gut microbiota: implications for metabolic health. [PDF]
Ali N.
europepmc +1 more source

