Results 151 to 160 of about 65,785 (311)

Distinct classes of gut bacterial molybdenum-dependent enzymes produce urolithins. [PDF]

open access: yesProc Natl Acad Sci U S A
Bae M   +7 more
europepmc   +1 more source

Untersuchungen zum Ursprung der Substratspezifität von Enzymen der Amidohydrolase‐Superfamilie

open access: yesAngewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Umfassende Analysen zweier Enzymklassen aus der Amidohydrolase‐Superfamilie (AHS) ergaben, dass die Katalyse über eine 1,4‐ bzw. 1,6‐nukleophile konjugierte Addition abläuft und diese Eigenschaft die Substratspezifität bestimmt. Obwohl alle Substrate und Produkte vollständig achiral sind, führt dieser mechanistische Unterschied zu einer invertierten ...
Lukas Drexler   +3 more
wiley   +1 more source

Xanthine Oxidase-Dependent Activation of NLPR3 Inflammasome in Epithelial Cells Sustains Inflammation in Inflammatory Bowel Disease. [PDF]

open access: yesInflamm Bowel Dis
Di Petrillo A   +15 more
europepmc   +1 more source

On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 4, 22 January 2026.
Comprehensive analyses of two enzyme classes from the amidohydrolase superfamily (AHS) revealed that catalysis proceeds either via 1,4 or 1,6 nucleophilic conjugate addition and that this property defines substrate specificity. Moreover, although all substrates and products are entirely achiral, this mechanistic difference results in an inverted ...
Lukas Drexler   +3 more
wiley   +1 more source

Phosphodiesterase Inhibitor 3-Isobutyl-1-Methyl-Xanthine Affects Ovarian Morphology and Stimulates Reproduction in Rabbits

open access: green, 2010
Alexander V. Sirotkin   +4 more
openalex   +2 more sources

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