Results 151 to 160 of about 112,529 (303)
Hyperuricaemia in type 1 Gaucher disease: is uric acid a biomarker for disease severity?
Abstract Background Elevated serum uric acid (SUA) levels were observed in Gaucher disease type 1 (GD1) patients followed for two decades in northern Israel. There are no previous reports regarding hyperuricaemia in GD1 patients. Aims We aimed to evaluate the frequency of hyperuricaemia in GD1 patients and its correlation to disease severity ...
Zufit Hexner‐Erlichman+4 more
wiley +1 more source
High uric acid (UA) facilitates diabetes progression and is responsible for developing other diseases, such as cardiovascular disease and renal disease. Lifestyle modifications could lower UA levels, but relevant evidence is required in patients with type 2 diabetes.
Jie Li, Ertao Zhang, Zhao Dong, Yan Liu
wiley +1 more source
This study reveals that our self‐developed xanthine derivative, KMUP‐3, suppresses osteoclastogenesis, inflammation, and pyroptosis by inhibiting the NLRP3 inflammasome. It also alleviates periodontal bone loss in periodontitis rats, highlighting its potential as a novel therapeutic option for periodontitis.
Shang‐En Huang+7 more
wiley +1 more source
The reduction of cytochrome c by hypoxanthine and xanthine oxidase [PDF]
D.B. Morell
openalex +1 more source
RNA elements and their biotechnological applications in plants
Summary Engineering of plants for improved traits and efficient heterologous protein production can be achieved by modifying or introducing cis‐ or trans‐acting RNA elements. The function of these elements depends not only on their nucleotide sequence but also on their highly dynamic higher order structures.
Filip Lastovka+3 more
wiley +1 more source
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn+12 more
wiley +1 more source
Factors influencing xanthine oxidase activity in rat skin [PDF]
Walter D. Block, Doris V. Johnson
openalex +1 more source