Results 91 to 100 of about 34,724 (282)

Reduction of leukocyte microvascular adherence and preservation of blood-brain barrier function by superoxide-lowering therapies in a piglet model of neonatal asphyxia [PDF]

, 2019
Background: Asphyxia is the most common cause of brain damage in newborns. Substantial evidence indicates that leukocyte recruitment in the cerebral vasculature during asphyxia contributes to this damage. We tested the hypothesis that superoxide radical (
Aarti R. Shah, Aarti R. Shah, Ernesto R. Gonzales, Jacob B. Ruden, Jeffrey M. Gidday, Kevin L. Quick, Laura L. Dugan, Laura L. Dugan, Nan Kennedy, T. S. Park   +9 more
core   +2 more sources

Early adversity and the comorbidity between metabolic disease and psychopathology

The Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas, Patricia Pelufo Silveira   +1 more
wiley   +1 more source

Relationship between plasma xanthine oxidoreductase activity and left ventricular ejection fraction and hypertrophy among cardiac patients.

PLoS ONE, 2017
Background and purposeXanthine oxidoreductase (XOR), which catalyzes purine catabolism, has two interconvertible forms, xanthine dehydrogenase and xanthine oxidase, the latter of which produces superoxide during uric acid (UA) synthesis.
Yuki Fujimura, Yohei Yamauchi, Takayo Murase, Takashi Nakamura, Shu-Ichi Fujita, Tomohiro Fujisaka, Takahide Ito, Koichi Sohmiya, Masaaki Hoshiga, Nobukazu Ishizaka   +9 more
doaj   +1 more source

Evaluation of Oxidative Stress in Red Blood Cells From Vitiligo Patients and Its Correlation With Disease Severity and Activity: A Cohort Case-Control Study. [PDF]

Health Sci Rep
ABSTRACT Background Exact pathogenesis of vitiligo is still ambiguous. Different theories explain the loss of melanocytes, such as autoimmune, biochemical, autocytotoxic, metabolic theories, or neural dysfunction theories. None of these theories have been proved yet.
Saleh YSN, Mohammed GF, Anani M, Bandy A, Bahaj SS, Marie RE.   +5 more
europepmc   +2 more sources

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

Bench-to-bedside review : targeting antioxidants to mitochondria in sepsis [PDF]

, 2010
Peer reviewedPublisher ...
A Dhanasekaran, A Dyson, A Filipovska, AL Hill, AM James, B Bedogni, BE Minter, CA Macias, CC Chuang, CE Cross, D Brealey, D Brealey, D Brealey, D Graham, DA Lowes, DA Lowes, DP Jones, E Borrelli, ED Crouser, ED Crouser, F Arnalich, FN Gellerich, G Escames, G Escames, GF Kelso, GS Supinski, H Bayir, H Bohrer, H Zhang, HC Cowley, Helen F Galley, HF Galley, HF Galley, HF Galley, HF Goode, I Spasojević, I Vanhorebeek, J Ripcke, JC Marshall, JF Turrens, JJ Pandit, JV Esplugues, K Yassen, K Zhao, KS Roser, L Packer, M Qunitero, MD Wheeler, MD Wheeler, MP Fink, MP Fink, MP Murphy, MW Fariss, P Ghafourifar, P Wipf, RAJ Smith, RAJ Smith, RL Paterson, RO Poyton, S González-Rubio, S Rinaldi, SS Sheu, V Mishra, V Vanasco, VJ Adlam, VP Skulachev, W Droge, Z Lacza   +67 more
core   +2 more sources

Lifestyle implications of the paradox and management of oxidative stress in sperm

The Journal of Physiology, EarlyView.
Abstract figure legend Lifestyle factors influencing male fertility. Schematic overview of lifestyle factors with beneficial (left) and detrimental (right) effects on male fertility. A balanced diet, regular moderate physical activity and stress management strategies support sperm function and redox homeostasis.
Giuseppe T. Patané, Ruben J. Moreira, Annamaria Russo, Maria L. Pereira, Pedro F. Oliveira, Davide Barreca, Marco G. Alves   +6 more
wiley   +1 more source

Malondialdehyde as an independent predictor of body mass index in adolescent girls [PDF]

Journal of Medical Biochemistry, 2023
Background: Given the fact that the studies that examined oxidative stress in relation to obesity that included late adolescents are scarce and show inconclusive results we aimed to investigate a wide spectrum of nitro-oxidative stress biomarkers i.e ...
Klisic Aleksandra, Malenica Maja, Kostadinovic Jelena, Kocic Gordana, Ninic Ana   +4 more
doaj  

Iso‐Nanozymes of Atomically Precise Copper Nanoclusters

Aggregate, Volume 7, Issue 2, February 2026.
This study introduces the novel concept of “iso‐nanozymes” through the application of atomically precise copper nanoclusters (Cu30/Cu32) to elucidate structure–activity relationships. The removal of two PPh3Cu+ units from Cu30 enhances its peroxidase‐like activity by 6.5‐fold relative to Cu32.
Jing Sun, Mengke Wang, Zong‐Jie Guan, Yunqing Kang, Xueli Sun, Yishu Wang, Rong Huo, Xuekun Gong, Xiaoxuan Xu, Chengrui Xin, Simin Li, Yusuke Yamauchi, Nanfeng Zheng, Xiyun Yan, Qingxiang Guo, Hui Shen   +15 more
wiley   +1 more source

Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity [PDF]

, 2015
Correction of human myeloid cell function is crucial for the prevention of inflammatory and allergic reactions as well as leukaemia progression. Caffeine, a naturally occurring food component, is known to display anti-inflammatory effects which have ...
Abooali, Maryam, Berger, Steffen M., Casely-Hayford, Maxwell A., Fasler-Kan, Elizaveta, Gibbs, Bernhard F., Gonçalves Silva, Isabel, Prokhorov, Alexandr, Sumbayev, Vadim V., Yasinska, Inna M.   +8 more
core   +3 more sources