Results 11 to 20 of about 34,724 (282)

Modulation of IRAK4 as a therapeutic strategy against monosodium urate- and xanthine-induced inflammation in macrophages and HepG2 cells [PDF]

Frontiers in Immunology
BackgroundInterleukin-1 receptor-associated kinase 4 (IRAK4) is a pivotal mediator of Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) signaling, critically involved in innate immune activation and pro-inflammatory cytokine production ...
Sadiq Umar, Huan T. Chang, Huan T. Chang, Mark Maienschein-Cline, Sriram Ravindran   +4 more
doaj   +2 more sources

Kinetic mechanism of chicken liver xanthine dehydrogenase [PDF]

Biochemical Journal, 1988
The kinetic behaviour of chicken-liver xanthine dehydrogenase (xanthine/NAD+ oxidoreductase; EC 1.2.1.37) has been studied. Steady-state results, obtained from a wide range of concentrations of substrates and products, were fitted by rational functions of degree 1:1, 1:2, 2:2 and 3:3 with respect to substrates, and 0:1, 1:1, 0:2 and 1:2 with regard to ...
Pau Bruguera, Antonio López-Cabrera, Enric I. Canela   +2 more
openalex   +4 more sources

The reductive half-reaction of xanthine dehydrogenase from Rhodobacter capsulatus: the role of Glu232 in catalysis. [PDF]

J Biol Chem, 2014
Hall J, Reschke S, Cao H, Leimkühler S, Hille R.   +4 more
europepmc   +3 more sources

A rice XANTHINE DEHYDROGENASE gene regulates leaf senescence and response to abiotic stresses

Crop Journal, 2022
Xanthine dehydrogenase, a member of the molybdenum enzyme family, participates in purine metabolism and catalyzes the generation of ureides from xanthine and hypoxanthine.
Jiangmin Xu, Chenyang Pan, Han Lin, Hanfei Ye, Sheng Wang, Tao Lu, Qianyu Chen, Kairu Yang, Mei Lu, Qian Qian, Deyong Ren, Yuchun Rao   +11 more
doaj   +1 more source

Studies on Avian Xanthine Dehydrogenases

Journal of Biological Chemistry, 1965
Cornelius F. Strittmatter
openalex   +2 more sources

Xanthine dehydrogenase-1 silencing in Aedes aegypti mosquitoes promotes a blood feeding-induced adulticidal activity. [PDF]

FASEB J, 2017
Isoe J, Petchampai N, Isoe YE, Co K, Mazzalupo S, Scaraffia PY.   +5 more
europepmc   +2 more sources

Association of Mutations Identified in Xanthinuria with the Function and Inhibition Mechanism of Xanthine Oxidoreductase

Biomedicines, 2021
Xanthine oxidoreductase (XOR) is an enzyme that catalyzes the two-step reaction from hypoxanthine to xanthine and from xanthine to uric acid in purine metabolism.
Mai Sekine, Ken Okamoto, Kimiyoshi Ichida   +2 more
doaj   +1 more source

Association of Xanthine Oxidase and Neutrophil Activation Marker Elastase in Preeclampsia: A Case-control Study [PDF]

Journal of Clinical and Diagnostic Research, 2021
Introduction: Preeclampsia is an obstetric emergency for both mother and the foetus with unknown aetiology. Delivery is the only effective way in the prompt management.
Ramya Rajshekar, Vanishree Bambrana, CHIKKANAYAKANAHALLI Doddaiah Dayanand, Payal Ray, D Radhika   +4 more
doaj   +1 more source

Xanthine dehydrogenase/xanthine oxidase and oxidative stress [PDF]

AGE, 1997
Xanthine dehydrogenase (XDH) and xanthine oxidase (XOD) are single-gene products that exist in separate but interconvertible forms. XOD utilizes hypoxanthine or xanthine as a substrate and O2 as a cofactor to produce superoxide (·O2 (-)) and uric acid.
H Y, Chung, B S, Baek, S H, Song, M S, Kim, J I, Huh, K H, Shim, K W, Kim, K H, Lee   +7 more
openaire   +2 more sources

Exogenous application of xanthine and uric acid and nucleobase-ascorbate transporter MdNAT7 expression regulate salinity tolerance in apple

BMC Plant Biology, 2021
Background Soil salinity is a critical threat to global agriculture. In plants, the accumulation of xanthine activates xanthine dehydrogenase (XDH), which catalyses the oxidation/conversion of xanthine to uric acid to remove excess reactive oxygen ...
Tingting Sun, Tingting Pei, Lulu Yang, Zhijun Zhang, Mingjun Li, Yuerong Liu, Fengwang Ma, Changhai Liu   +7 more
doaj   +1 more source