Results 51 to 60 of about 16,447 (208)
First case of hereditary xanthinuria in a Moroccan family
PAMJ Clinical Medicine, 2019 The xanthinuria is a rare hereditary autosomal recessive disease. It is related to xanthine oxidase deficiency also known as xanthine dehydrogenase, an enzyme involved in the metabolism of purine bases.
Aicha Ezoubeiri +4 more
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Plant, Cell &Environment, EarlyView.ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn +12 more
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Xanthine Oxidase and Xanthine Dehydrogenase from an Estivating Land Snail
Zeitschrift für Naturforschung C, 1995 Abstract During arousal from estivation in land snails. Otala lactea, active metabolic functions are restored within minutes and oxygen consumption increases dramatically. During the transition from the hypoxic conditions of estivation to normoxia it is possible that xanthine oxidase (XO ) in hepatopancreas contributes to the observed ...
Kenneth B. Storey, Marcelo Hermes-Lima
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The Role of Xanthine Oxidase in Pregnancy Complications: A Systematic Review
AntioxidantsXanthine oxidoreductase (XOR) is an enzyme involved in the oxidation of hypoxanthine and xanthine to uric acid. XOR has two isoforms: xanthine dehydrogenase and xanthine oxidase (XO).
Lorenzo Annesi +3 more
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Early adversity and the comorbidity between metabolic disease and psychopathology
The Journal of Physiology, EarlyView.Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas +1 more
wiley +1 more source
The role of xanthine dehydrogenase / xanthine oxidase in atherogenesis in patients with hyperlipidaemia [PDF]
Jugoslovenska medicinska biohemija, 2003 The activity of xanthine dehydrogenase/xanthine oxidase has been a target of considerable interest. In the metabolic pathway of purines, XO catalyzes the oxidation of xanthine and hypoxanthine to uric acid and thereby produces reactive oxygen metabolites.
Slavica Kundalic +4 more
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Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury
The Journal of Physiology, EarlyView.Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich +5 more
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Oxidative Stress: Signaling Pathways, Biological Functions, and Disease
MedComm, Volume 6, Issue 7, July 2025.Oxidative stress causes cellular damage across multiple systems, contributing to neurodegeneration (Alzheimer's, Parkinson's, Huntington's), cancer progression and resistance, cardiovascular diseases (atherosclerosis, heart failure), liver and kidney injury, metabolic disorders (diabetes, obesity), autoimmune diseases, musculoskeletal decline, retinal ...
Sixuan Liu +4 more
wiley +1 more source
Lack of conversion of xanthine dehydrogenase to xanthine oxidase during warm renal ischemia [PDF]
FEBS Letters, 1990 Irreversible transformation of xanthine dehydrogenase (XDH) to xanthine oxidase (XO) during ischemia was determined measuring XDH and total enzyme activity in kidneys before and after 60 min of clamp of the renal pedicle. Tissue levels of adenine nucleotides, xanthine and hypoxanthine were used as indicators of ischemia.
G. CIGHETTI +3 more
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Xanthine oxidoreductase: One enzyme for multiple physiological tasks
Redox Biology, 2021 Human xanthine oxidoreductase (XOR) is a multiple-level regulated enzyme, resulting from a complicated evolutionary process that assigned it many physiological roles.
Massimo Bortolotti +3 more
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