Results 91 to 100 of about 299,059 (319)

Diabetic Cardiovascular Disease Induced by Oxidative Stress. [PDF]

open access: yes, 2015
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality among patients with diabetes mellitus (DM). DM can lead to multiple cardiovascular complications, including coronary artery disease (CAD), cardiac hypertrophy, and heart failure
Adam, Matti   +9 more
core   +2 more sources

Therapeutic Effects of Xanthine Oxidase Inhibitors: Renaissance Half a Century after the Discovery of Allopurinol

open access: yesPharmacological Reviews, 2006
The prototypical xanthine oxidase (XO) inhibitor allopurinol, has been the cornerstone of the clinical management of gout and conditions associated with hyperuricemia for several decades.
P. Pacher, A. Nivorozhkin, C. Szabó
semanticscholar   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

PENGHAMBATAN AKTIVITAS XANTHINE OXIDASE OLEH EKSTRAK ETANOL AKAR SAMBILOTO (Andrographis paniculata, Ness) SECARA IN VITRO

open access: yesPharmaciana, 2012
Sambiloto root of which contained of flavonoids used by the people for traditional medicine. In the previous publication, an effective xanthine oxidase inhibitory activity of flavonoids was reported.
Ulfah Septianingsih   +2 more
doaj   +1 more source

Identification of a new mutation in the human xanthine dehydrogenase responsible for xanthinuria type I

open access: yesAdvances in Laboratory Medicine, 2021
Hereditary xanthinuria is a rare, autosomal and recessive disorder characterized by severe hypouricemia and increased xanthine excretion, caused by a deficiency of xanthine dehydrogenase/oxidase (XDH/XO, EC: 1.17.1.4/1.17.3.2) in type I, or by a ...
Collazo Abal Cristina   +5 more
doaj   +1 more source

In Vitro α-Amylase, α-Glucosidase, Pancreatic Lipase, Xanthine Oxidase Inhibiting Activity of Agaricus bisporus Extracts

open access: yesMycobiology, 2023
In this study, the α-amylase inhibitory activity, α-glucosidase inhibitory activity, pancreatic lipase inhibitory activity, and Xanthine Oxidase inhibitory activity of the fruiting body extracts of 5 varieties of Agaricus bisporus (AB) were confirmed ...
Jung Han Kim   +2 more
doaj   +1 more source

Sensitive superoxide detection in vascular cells by the new chemiluminescence dye L-012 [PDF]

open access: yes, 1999
The detection superoxide production in vascular cells is usually limited by a low sensitivity of available assays, We tested the applicability of the luminol derivate L-012 {[}8-amino-5-chloro-7-phenylpyridol{[}3,4-d]pyridazine-l,4(2H,3H)dione] to ...
Gloe, Torsten   +4 more
core   +1 more source

Inhibition of Xanthine Oxidase by Flavonoids [PDF]

open access: yesBioscience, Biotechnology, and Biochemistry, 1999
Various dietary flavonoids were evaluated in vitro for their inhibitory effect on xanthine oxidase, which has been implicated in oxidative injury to tissue by ischemia-reperfusion. Xanthine oxidase activity was determined by directly measuring uric acid formation by HPLC.
Michiko Seki   +2 more
openaire   +3 more sources

Guidelines for Studying the Oxidative Stress Damage Model on Drosophila melanogaster

open access: yesFuture Postharvest and Food, EarlyView.
This guideline introduced Drosophila as a research model to summarize in detail the research methods of indicators that can characterize oxidative stress. It generally includes four aspects such as generation of ROS, damage caused by ROS, antioxidant defense, and cell stress repair and apoptosis.
Quanyong Wu
wiley   +1 more source

An investigation of the antiplatelet effects of succinobucol (AGI-1067) [PDF]

open access: yes, 2016
Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet–platelet and platelet–vessel wall interactions, the aim of this study was to establish if antioxidant ...
Gnanadesika, Sukanya   +3 more
core   +1 more source

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