Results 21 to 30 of about 300,913 (307)
Xanthine oxidase inhibitory activity of Arcangelisia flava
Acta Biochimica Indonesiana, 2022 Background: Hyperuricemia is characterized by elevated levels of uric acid in the blood, produced from its precursor's xanthine and hypoxanthine via xanthine oxidase.
Fatmawati +5 more
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Clinical Effects of Xanthine Oxidase Inhibitors in Hyperuricemic Patients
Medical Principles and Practice, 2020 This review aims to critically present the available clinical evidence supporting the treatment of chronic hyperuricemia with xanthine oxidase inhibitors.
A. Cicero +4 more
semanticscholar +1 more source
Definitions, 2020 Any substance that inhibits xanthine oxidase, an enzyme that catalyzes the oxidation of hypoxanthine to xanthine and xanthine to uric acid, along with the generation of reactive oxygen species (ROS).
見永 武芳
semanticscholar +1 more source
Hepatology, EarlyView., 2022 A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan +19 more
wiley +1 more source
Eicosapentaenoic acid and oxypurinol in the treatment of muscle wasting in a mouse model of cancer cachexia [PDF]
, 2012 Cancer cachexia is a wasting condition, driven by systemic inflammation and oxidative stress. This study investigated eicosapentaenoic acid (EPA) in combination with oxypurinol as a treatment in a mouse model of cancer cachexia. Mice with cancer cachexia
Hinch, Edward +4 more
core +11 more sources
Molecules, 2023 Dioscoreae hypoglaucae Rhizoma (DH) and Dioscoreae spongiosae Rhizoma (DS) are two similar Chinese herbal medicines derived from the Dioscorea family. DH and DS have been used as medicines in China and other Asian countries for a long time, but study on ...
Guo Rui +6 more
doaj +1 more source
Effect of oxidative stress on the activity of human osteoblastic MG63 cells
口腔疾病防治, 2017 Objective To investigate the morphology and proliferation viability in oxidative stress induced damage in human MG63 cells. Methods The MG63 cells were treated with superoxide anion (O2.⁃) produced by different con⁃ centrations of xanthine/xanthine ...
WANG Qiong
doaj +1 more source
Xanthine dehydrogenase/xanthine oxidase and oxidative stress [PDF]
AGE, 1997 Xanthine dehydrogenase (XDH) and xanthine oxidase (XOD) are single-gene products that exist in separate but interconvertible forms. XOD utilizes hypoxanthine or xanthine as a substrate and O2 as a cofactor to produce superoxide (·O2 (-)) and uric acid.
Hae Young Chung +7 more
openaire +2 more sources
Novel perspectives in redox biology and pathophysiology of failing myocytes: modulation of the intramyocardial redox milieu for therapeutic interventions - A review article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology [PDF]
, 2016 The prevalence of heart failure (HF) is still increasing worldwide, with enormous human, social, and economic costs, in spite of huge efforts in understanding pathogeneticmechanisms and in developing effective therapies that have transformed this ...
Angelini, Annalisa +8 more
core +9 more sources
Screening medicinal plant extracts for xanthine oxidase inhibitory activity
Тонкие химические технологии, 2022 Objectives. The study aimed to test the ethanol extracts of ten medicinal plants for xanthine oxidase inhibitory activity.Methods. The degree of xanthine oxidase inhibitory activity was determined by measuring the absorbance spectrophotometrically at 290
A. C. Ha, Ch. D.P. Nguyen, T. M. Le
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