Results 21 to 30 of about 78,058 (260)

Optimization of Ultrasound-Assisted Extraction of Ilex latifolia Thunb. Polysaccharide and Its Effect on the Inhibitory Activity of Xanthine Oxidase

open access: yesShipin gongye ke-ji, 2023
Objective: To optimize the extraction process of Ilex latifolia Thunb. polysaccharide and analyze its inhibitory activity of xanthine oxidase. Methods: A response surface optimization ultrasound-assisted method was used to study the effects of material ...
Zhongying LU, Mengqin ZHANG, Xiang CHEN
doaj   +1 more source

Crucial involvement of xanthine oxidase in the intracellular signalling networks associated with human myeloid cell function [PDF]

open access: yes, 2014
Xanthine oxidase (XOD) is an enzyme which plays a central role in purine catabolism by converting hypoxanthine into xanthine and then further into uric acid.
Abooali, Maryam   +5 more
core   +1 more source

Antihyperurisemic Activity of Aqueous Celery Infusion by Xanthine Oxidase Enzyme Inhibition

open access: yesMajalah Obat Tradisional, 2018
Hyperuricemia is a metabolic disorder because of excessive uric acid production. The high prevalence of hyperuresemia in the world, especially in Indonesia makes the research of antihyperurisemia drugs very needed today.
Atiqoh Zummah, Rahma Diyan Martha
doaj   +1 more source

Pharmacology and clinical drug candidates in redox medicine [PDF]

open access: yes, 2015
SIGNIFICANCE Oxidative stress is suggested to be a disease mechanism common to a wide range of disorders affecting human health. However, so far, the pharmacotherapeutic exploitation of this, for example, based on chemical scavenging of pro-oxidant ...
Casas, Ana I   +11 more
core   +2 more sources

Inhibition of Xanthine Oxidase Activity by Ethanolic Extract of Piperomia pellucida L., Acacypha indica L. and Momordica charantia L.

open access: yesIndonesian Biomedical Journal, 2016
BACKGROUND: Uric acid is a final result of purine catabolism, the enzymatic reactions in the body cells from amino acids or ribonucleotide dinucleotide. Peperomia pellucida L. (P. pellucida), Acalypha indica L. (A. indica) and Momordica charantia L.
Parawansah Parawansah   +3 more
doaj   +1 more source

Exercise Training Ameliorates Renal Oxidative Stress in Rats with Chronic Renal Failure

open access: yesMetabolites, 2022
In patients with chronic kidney disease, exercise training with moderate intensity protects renal function and improves mortality. However, the mechanisms of the renal protective effects of exercise training in chronic kidney disease have not been ...
Seiko Yamakoshi   +4 more
doaj   +1 more source

Reduction of leukocyte microvascular adherence and preservation of blood-brain barrier function by superoxide-lowering therapies in a piglet model of neonatal asphyxia [PDF]

open access: yes, 2019
Background: Asphyxia is the most common cause of brain damage in newborns. Substantial evidence indicates that leukocyte recruitment in the cerebral vasculature during asphyxia contributes to this damage. We tested the hypothesis that superoxide radical (
Aarti R. Shah   +9 more
core   +2 more sources

Cardiovascular and hepatic toxicity of cocaine: potential beneficial effects of modulators of oxidative stress [PDF]

open access: yes, 2015
Oxidative stress (OS) is thought to play an important role in the pharmacological and toxic effects of various drugs of abuse. Herein we review the literature on the mechanisms responsible for the cardiovascular and hepatic toxicity of cocaine with ...
Antonilli, Letizia   +5 more
core   +9 more sources

Participation of reactive oxygen species in regulation of Са2+ - activated К + channels of erythrocytes

open access: yesБюллетень сибирской медицины, 2009
In this study, we investigated the effects of preincubation with the reactive oxygen species-generating system xanthine oxidase/xanthine on Ca2+-dependent potassium permeability of erythrocyte membrane. The increase of intracellular calcium concentration
O. A. Trubacheva   +6 more
doaj   +1 more source

Alleviation of Hyperuricemia by Strictinin in AML12 Mouse Hepatocytes Treated with Xanthine and in Mice Treated with Potassium Oxonate

open access: yesBiology, 2023
Hyperuricemia, an abnormally high level of blood uric acid, is a major risk factor for gout. Although xanthine oxidase inhibitors were clinically used to lower blood uric acid level, the concerned side effects restricted their utilization. In this study,
Kuo-Ching Huang   +8 more
doaj   +1 more source

Home - About - Disclaimer - Privacy