Results 1 to 10 of about 6,368 (267)
Effect of caffeine and other xanthines on liver sinusoidal endothelial cell ultrastructure [PDF]
Scientific Reports, 2023 Xanthines such as caffeine and theobromine are among the most consumed psychoactive stimulants in the world, either as natural components of coffee, tea and chocolate, or as added ingredients.
Hong Mao +12 more
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Experimental and Theoretical Studies on Acid Corrosion Inhibition of API 5L X70 Steel with Novel 1-N-α-d-Glucopyranosyl-1H-1,2,3-Triazole Xanthines [PDF]
Molecules, 2023 A series of novel 1-N-α-d-glucopyranosyl-1H-1,2,3-triazole xanthines was synthesized from azido sugars (glucose, galactose, and lactose) and propargyl xanthines (theophylline and theobromine) using a typical copper (I)-catalyzed azide–alkyne 1,3-dipolar ...
Alma Sánchez-Eleuterio +9 more
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Recent Advances in the Synthesis of Xanthines: A Short Review [PDF]
Scientifica, 2022 Xanthine and its derivatives are considered a pharmacologically potential moiety that manifests immense biological activities. Owing to this much diversity in the biological field, this scaffold has fascinated the attention of many researchers around the
Anandi Kapri, Nitin Gupta, Sumitra Nain
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Diagnosing Parkinson’s disease and monitoring its progression: Biomarkers from combined GC-TOF MS and LC-MS/MS untargeted metabolomics [PDF]
HeliyonParkinson's disease (PD) is a prevalent neurodegenerative disorder with a poorly understood etiology. An accurate diagnosis of idiopathic PD remains challenging as misdiagnosis is common in routine clinical practice.
Lina A. Dahabiyeh +4 more
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Molecules, 2021 Antimicrobial resistance is a major healthcare threat globally. Xanthines, including caffeine and pentoxifylline, are attractive candidates for drug repurposing, given their well-established safety and pharmacological profiles.
Anna Woziwodzka +6 more
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Metals, 2022 Metals stability and corrosion resistance are very important factors that influence the possibility of their applications. In order to study and foresee the behavior of metals during various applications in all kinds of conditions and media, numerous ...
Marija B. Petrović Mihajlović +4 more
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Pharmaceuticals, 2021 As life expectancy increases, dementia affects a growing number of people worldwide. Besides current treatments, phosphodiesterase 9 (PDE9) represents an alternative target for developing innovative small molecules to contrast neurodegeneration.
Giovanni Ribaudo +2 more
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eLife, 2021 Mutations in TP53 occur commonly in the majority of human tumors and confer aggressive tumor phenotypes, including metastasis and therapy resistance. CB002 and structural-analogs restore p53 signaling in tumors with mutant-p53 but we find that unlike ...
Liz Hernandez Borrero +8 more
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Chemistry, 2021 In this paper, a simple and clean process for the alkylation and arylation of nitrogen-containing heterocycles is reported. The reactions were conducted using the Q-tube® as a non-conventional technology, in water as a green solvent, at overboiling ...
Cecilia Scimmi +7 more
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Effects of early aminophylline therapy on clinical outcomes in premature infants
Pediatrics and Neonatology, 2023 Background: Aminophylline use and the association between clinical outcomes and therapy timing have been less investigated. The objective of this study was to determine the efficacy of early aminophylline use (within the first two days of life) in ...
Yi-Ting Chu +6 more
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