Results 91 to 100 of about 980 (152)

Design and Synthesis of β-O-Glucosylated 5-(Arylidene)-6-Aminouracils: Towards Water-Soluble 8-Aryl Xanthines as Effective Enzyme Inhibitors

open access: yes
8-Aryl xanthines are selective enzyme inhibitors modified from naturally occurring methylxanthines. However, the low water solubility of substituted xanthines restricts their clinical applications.
Telli, Fatma Çetin   +7 more
core   +1 more source

Psychoactive substance consumption by Portuguese population [PDF]

open access: yes, 2019
BACKGROUND: Increasing consumption of psychoactive substances is a major social concern worldwide. OBJECTIVES: To investigate the prevalence of psychoactive substances consumption in the Portuguese population, lifetime and recently, the main reasons for
Pinto, Isabel C.   +4 more
core  

Mammalian Xanthine Oxidoreductase – Mechanism of Transition From Xanthine Dehydrogenase to Xanthine Oxidase

FEBS Journal, 2008
Reactive oxygen species are generated by various biological systems, including NADPH oxidases, xanthine oxidoreductase, and mitochondrial respiratory enzymes, and contribute to many physiological and pathological phenomena. Mammalian xanthine dehydrogenase (XDH) can be converted to xanthine oxidase (XO), which produces both superoxide anion and ...
Emil F. Pai   +2 more
exaly   +3 more sources

Xanthine oxidase and xanthine dehydrogenase

The FASEB Journal, 1995
Xanthine oxidase and xanthine dehy‐drogenase are enzymes involved in the metabolism of purines and pyrimidines in various organisms. Their relationship to one another has been the subject of considerable debate, primarily because of their proposed roles in ischemia/reperfasion damage in tissues.
Russ Hille, Takeshi Nishino
openaire   +1 more source

Xanthine urolithiasis

Urology, 2006
Xanthine calculi are uncommonly encountered stones. When they occur, they typically do so in association with inborn metabolic disorders such as hereditary xanthinuria or Lesch-Nyhan syndrome. They may also occur in association with states of profound hyperuricemia such as myeloproliferative disease after treatment with allopurinol.
Vernon M, Pais   +4 more
openaire   +2 more sources

The reactions of chloroperoxidase in the presence of xanthine/xanthine oxidase

Biochemical and Biophysical Research Communications, 1989
Spectral data are presented which indicate that chloroperoxidase is converted to compound II during the reaction with superoxide/hydrogen peroxide generated in the xanthine/xanthine oxidase system. Upon completion of compound II formation, compound II returns back to the native state of chloroperoxidase without formation of detectable intermediates. It
D, Metodiewa, M, Pickard, H B, Dunford
openaire   +2 more sources

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