Results 81 to 90 of about 4,011 (296)

Effect of fermentation time on the content of bioactive compounds with cosmetic and dermatological properties in Kombucha Yerba Mate extracts

open access: yesScientific Reports, 2021
Kombucha is a beverage made by fermenting sugared tea using a symbiotic culture of bacteria belonging to the genus Acetobacter, Gluconobacter, and the yeasts of the genus Saccharomyces along with glucuronic acid, which has health-promoting properties ...
Aleksandra Ziemlewska   +5 more
doaj   +1 more source

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

open access: yesAdvanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang   +5 more
wiley   +1 more source

Synthèse de nouvelles xanthines, dérivées de 2-amino-2-oxazolines, antagonistes potentiels des récepteurs de l'adenosine [PDF]

open access: yes, 2005
Ce travail de thèse nous a permis de synthétiser un grand nombre de nouveaux dérivés de type 1- ou 3-[2-hydroxy-3-aryloxypropyl]xanthines. Ces composés ont été obtenus à partir d'un synthon original de type amidine, les 2-amino-2-oxazolines.
JARRY, Christian, MASSIP, Stéphane
core  

Antioxidant effect of naturally occurring xanthines on the oxidative damage of DNA bases [PDF]

open access: yes, 2017
The repair of the oxidised radicals of adenine and guanosine by several naturally occurring xanthines was studied. Each pair of DNA purine/xanthine was made to react with the sulphate radical and the decrease of the concentration of both compounds was ...
R. M.B. Dias   +4 more
core   +1 more source

Cafeína: revisão sobre métodos de análise Analytical methods for caffeine

open access: yesQuímica Nova, 2007
Gravimetric and Bailey-Andrew methods are tedious and provide inflated results. Spectrofotometry is adequate for caffeine analysis but is lengthy. Gas chromatography also is applied to the caffeine analysis but derivatization is needed.
Carlos A. B. De Maria   +1 more
doaj   +1 more source

From Sourcing to End‐of‐Life: Sustainability Challenges and Opportunities in Organic Bioelectronics

open access: yesAdvanced Science, EarlyView.
Organic bioelectronics bridges biology and electronics using organic mixed ionic/electronic conductors. This Perspective addresses sustainability across the full lifecycle of organic bioelectronic materials and devices, offering a framework to guide material sourcing, synthesis, fabrication, application, and end‐of‐life strategies toward bioelectronic ...
Gwennaël Dufil   +3 more
wiley   +1 more source

Separation of xanthines in hydro-organic and polar-organic elution modes on a titania stationary phase. [PDF]

open access: yes, 2014
International audienceHydrophilic interaction LC was investigated in hydro-organic and nonaqueous elution modes on a titania column by using a set of N-methyl xanthines as neutral polar probes.
Lassalle, Yannick   +2 more
core   +1 more source

Effects of substituent size upon adenosine receptor A1/A2 affinity of some newly synthesised 8-cycloalkyl xanthines. [PDF]

open access: yes, 1995
The activity of a series of 1,3-dipropyl-xanthines bearing C8-cycloalkyl substituents as antagonists at A1 and A2 adenosine receptors is examined. Pharmacological results showed that the size of the 8-substituent is an important feature for response in ...
Corsano S   +5 more
core  

SYNTHESIS AND PHYSICAL-CHEMICAL PROPERTIES OF WATER-SOLUBLE 3-BENZYLXANTHINE DERIVATIVES

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Introduction Nowadays, research of novel biological active compounds with low toxicity, are carried out among different classes of organic compounds of natural and synthetic genesis.
K. V. Аleksandrova   +3 more
doaj   +1 more source

Synthesis and physical-chemical properties of 3-benzyl-8-(5-mercapto-4-phenyl-[1,2,4]-triazole-3-ylmethylthiomethyl)xanthine and its s-substituted derivatives

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Aim. Currently, researches, devoted to obtain new active compounds, are carried out among various classes of organic compounds, and combination of several active heterocyclic fragments in one molecule is considered the key way in such researches ...
K. V. Аleksandrova   +4 more
doaj   +1 more source

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