Synthesis and physical-chemical properties of 3-benzyl-8-propylxanthine and its water-soluble salts
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016 Aim. Selection of basic compounds is a key moment of the novel drug substances development process. Nowadays, it is possible to model the properties of biologically active substances with the help of computer technologies and the special software.
E. K. Mikhal’chenko +2 more
doaj +1 more source
Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy
Advanced Science, EarlyView.Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan +14 more
wiley +1 more source
Stereochemical Evidence for Decomposition of Reactive Intermediates by Active Site Water in the Metabolism of 8-Alkyl Xanthines by P450 1A2 [PDF]
, 2016 Stereochemical Evidence for Decomposition of Reactive Intermediates by Active Site Water in the Metabolism of 8-Alkyl Xanthines by P450 ...
Kent L. Kunze (2144473) +1 more
core +1 more source
Advanced Science, EarlyView.Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
The combined action of methyl xanthines with erythromycin, chloramphenicol and tetracycline on Staphylococcus aureus [PDF]
, 1979 Caffeine and theophylline act synergistically with erythromycin against Staphylococcus aureus.
Rawal, B. D., Charles, B. G.
core
Mechanisms involved in anti-aging effects of guarana (Paullinia cupana) in Caenorhabditis elegans
Brazilian Journal of Medical and Biological Research, 2018 Guarana (Paullinia cupana) is habitually ingested by people in the Amazon region and is a key ingredient in various energy drinks consumed worldwide.
L.P. Arantes +8 more
doaj +1 more source
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2010 Hereditary xanthinuria type I, a defect of purine metabolism, results from a genetic deficiency of xanthine oxidase. It is an uncommon cause of stone formation in children. We report here two children with xanthine urolithiasis. The first patient was an 8-year-old boy who presented with repeated episodes of hematuria evaluated with excretory urography,
Gargah Tahar +4 more
openaire +2 more sources
Advanced Science, EarlyView.Single‐cell transcriptomics reveals the cellular response of Macrobrachium hainanense to carbonate alkalinity stress. Alkalinity stress impairs branchial ammonia excretion, induces mitochondrial dysfunction, and drives cell‐type‐specific changes in gills and hemocytes.
Yiting Jin +6 more
wiley +1 more source
The Effect of Insulin, Fluoride and Methyl Xanthines on the Hypothalamic-Parotid Gland Endocrine Axis [PDF]
, 1975 The purpose of this study was to determine the effect of insulin and fluoride on dentinal fluid movement (FM) in high-sucrose fed rats as mediated through the hypothalamic-parotid gland endocrine axis. In conjunction with the fluoride study, the possible
Ondler, Reagan
core
Synergistic effect of methyl-substituted xanthines and neomycin sulphate on Staphylococcus aureus and Pseudomonas aeruginosa in vitro [PDF]
, 1973 Methyl-substituted xanthines, caffeine and theophylline, potentiate the antimicrobial action of neomycin on Staphylococcus aureus and Pseudomonas œruginosa in vitro.
Rawal, B. D., Charles, B. G.
core +1 more source