Results 61 to 70 of about 980 (152)

SYNTHESIS AND PHYSICAL-CHEMICAL PROPERTIES OF WATER-SOLUBLE 3-BENZYLXANTHINE DERIVATIVES

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Introduction Nowadays, research of novel biological active compounds with low toxicity, are carried out among different classes of organic compounds of natural and synthetic genesis.
K. V. Аleksandrova, S. V. Levich, O. S. Shkoda, D. M. Yurchenko   +3 more
doaj   +1 more source

Synthesis and physical-chemical properties of 3-benzyl-8-(5-mercapto-4-phenyl-[1,2,4]-triazole-3-ylmethylthiomethyl)xanthine and its s-substituted derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Aim. Currently, researches, devoted to obtain new active compounds, are carried out among various classes of organic compounds, and combination of several active heterocyclic fragments in one molecule is considered the key way in such researches ...
K. V. Аleksandrova, A. S. Shkoda, S. V. Levich, M. V. Dyachkov, D. M. Yurchenko   +4 more
doaj   +1 more source

Determination of Flavonoids, Phenolic Acids, and Xanthines in Mate Tea (Ilex paraguariensis St.-Hil.)

Journal of Analytical Methods in Chemistry, 2013
Raw material, different formulations of foods, and dietary supplements of mate demands control of the content of bioactive substances for which high performance thin layer chromatography (TLC), described here, presents simple and rapid approach for ...
Mirza Bojić, Vicente Simon Haas, Darija Šarić, Željan Maleš   +3 more
doaj   +1 more source

3-Substituted Xanthines as Promising Candidates for Quadruplex Formation: Computational, Synthetic and Analytical Studies

, 2011
Our computational studies suggest that 3-substituted xanthines are good candidates for tetrad and quadruplex structures. 3-Methylxanthine (3MX) has been synthesized from 7-benzylxanthine, and the existence of tetrameric and octameric aggregates of 3MX ...
Bickelhaupt, F.M., Kele, Z., Célia Fonseca Guerra, Gyula Batta, Zoltán Kupihár, Pádár, P., Zupihára, Z., Zoltán Kele, Petra Pádár, Szolomájer, J., Kovács, L., János Szolomájer, Batta, G., Gábor Paragi, F. Matthias Bickelhaupt, Paragi, G., Fonseca Guerra, C.; id_orcid, Lajos Kovács   +17 more
core   +1 more source

The combined action of methyl xanthines with erythromycin, chloramphenicol and tetracycline on Staphylococcus aureus

, 1979
Caffeine and theophylline act synergistically with erythromycin against Staphylococcus aureus.
Rawal, B. D., Charles, B. G.
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Caffeine Consumption through Coffee: Content in the Beverage, Metabolism, Health Benefits and Risks

Beverages, 2019
Caffeine (1,3,7-trimethylxanthine) is the most consumed psychoactive substance in the world, acting by means of antagonism to adenosine receptors, mainly A1 and A2A.
Juliana dePaula, Adriana Farah
doaj   +1 more source

Xanthine scaffold: scope and potential in drug development

Heliyon, 2018
Medicinal plants have been the basis for discovery of various important marketed drugs. Xanthine is one such lead molecule. Xanthines in various forms (caffeine, theophylline, theobromine, etc) are abode in tea, coffee, cocoa, chocolate etc.
Nivedita Singh, Ashwinee Kumar Shreshtha, M.S. Thakur, Sanjukta Patra   +3 more
doaj   +1 more source

Synergistic effect of methyl-substituted xanthines and neomycin sulphate on Staphylococcus aureus and Pseudomonas aeruginosa in vitro

, 1973
Methyl-substituted xanthines, caffeine and theophylline, potentiate the antimicrobial action of neomycin on Staphylococcus aureus and Pseudomonas œruginosa in vitro.
Rawal, B. D., Charles, B. G.
core   +1 more source

Airway smooth muscle as a target of asthma therapy: history and new directions

Respiratory Research, 2006
Ultimately, asthma is a disease characterized by constriction of airway smooth muscle (ASM). The earliest approach to the treatment of asthma comprised the use of xanthines and anti-cholinergics with the later introduction of anti-histamines and anti ...
Killian Kieran, Janssen Luke J
doaj   +1 more source

Synthèse de nouvelles xanthines, dérivées de 2-amino-2-oxazolines, antagonistes potentiels des récepteurs de l'adenosine

, 2005
Ce travail de thèse nous a permis de synthétiser un grand nombre de nouveaux dérivés de type 1- ou 3-[2-hydroxy-3-aryloxypropyl]xanthines. Ces composés ont été obtenus à partir d'un synthon original de type amidine, les 2-amino-2-oxazolines.
JARRY, Christian, MASSIP, Stéphane
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