Results 101 to 110 of about 42,906 (302)

Actions of KMUP‐1, a xanthine and piperazine derivative, on voltage‐gated Na⁺ and Ca²⁺‐activated K⁺ currents in GH₃ pituitary tumour cells [PDF]

, 2015
Yi‐Ching Lo, Yu‐Ting Tseng, Chi‐Ming Liu, Bin‐Nan Wu, Sheng‐Nan Wu   +4 more
openalex   +1 more source

Single oral administration of dronabinol increases ocular blood flow in patients with glaucoma

Acta Ophthalmologica, EarlyView.
Abstract Purpose Glaucoma is a leading cause of irreversible blindness globally, primarily driven by elevated intraocular pressure (IOP). Still, some patients progress despite significant IOP lowering, potentially due to impaired ocular blood flow. This study aimed to evaluate the effects of dronabinol, a synthetic tetrahydrocannabinol derivative, on ...
Theresa Lindner, Viktoria Pai, Patrick Janku, Nikolaus Hommer, Anton Hommer, Marihan Abensperg‐Traun, Liudmyla Petric, Leopold Schmetterer, Gerhard Garhöfer, Doreen Schmidl   +9 more
wiley   +1 more source

Pyrogallol is a key component for xanthine oxidase inhibition by the leaves of Ammannia baecifera

, 2023
M. Rowshanul Habib, Yasuhiro Igarashi, Tao Zhou, Md. Abdul Aziz   +3 more
openalex   +2 more sources

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Update on diagnosis, nonpharmacological treatment and prevention of Equine Gastric Ulcer Syndrome (EGUS)

Equine Veterinary Education, EarlyView.
Summary The term Equine Gastric Ulcer Syndrome (EGUS) has been used since 1999. As there are important differences, the terms Equine Squamous Gastric Disease (ESGD) and Equine Glandular Gastric Disease (EGGD) were introduced in 2015. Risk factors like dietary management, training regimens and drug side effects, as described for NSAIDs, predispose ...
R. Lensing, A. K. Barton
wiley   +1 more source

A short peptide derived from late embryogenesis abundant proteins enhances acid tolerance in Escherichia coli via modulation of two‐component regulatory systems

The FEBS Journal, EarlyView.
Expression of the LEA‐K peptide in E. coli BL21 (DE3) improved bacterial viability under acidic stress (pH4), suggesting a protective function. RNA‐sequencing of LEA‐K‐expressing vs. non‐expressing cells revealed 283 differentially expressed genes (DEGs). In silico docking linked LEA‐K to two‐component systems (TCS) proteins (Rcs, BtsS/R, and EnvZ/OmpR)
Khaled Metwally, Shinya Ikeno
wiley   +1 more source

Exploring a Subpopulation of MASLD Associated With New Onset of CKD Using Supervised Clustering Techniques

Hepatology Research, EarlyView.
The supervised clustering of metabolic dysfunction‐associated steatotic liver disease (MASLD) using a SHapley Additive exPlanations (SHAP)‐converted matrix reveals distinct subpopulations that improved risk stratification for new onset of chronic kidney disease (CKD).
Itaru Hosaka, Marenao Tanaka, Tatsuya Sato, Yukinori Akiyama, Keitaro Nishizawa, Rie Matsumori, Hiroki Aida, Wataru Kawaharata, Kei Nakata, Koki Abe, Toru Suzuki, Hidemichi Kouzu, Naoya Yama, Nagisa Hanawa, Masato Furuhashi   +14 more
wiley   +1 more source

Synthesis of xanthine derivatives by microwave-assisted ring closure reaction [PDF]

, 2005
Joachim C. Burbiel, Jörg Hockemeyer, Christa E. Müller   +2 more
openalex   +1 more source

Elevated Salivary Theobromine and Long‐Term Improvement of Periodontal Health in Two Cohort Studies

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Background Theobromine, a methylxanthine mainly found in chocolate, has been suggested to possess various health‐promoting properties. This study aimed to investigate the long‐term effect of salivary theobromine levels on periodontitis severity using 7‐ and 10‐year follow‐up data from the prospective Studies of Health in Pomerania (SHIP‐TREND ...
Thomas Kocher, Sebastian‐Edgar Baumeister, Henry Völzke, Matthias Nauck, Peter Meisel, Karsten Suhre, Uwe Völker, Nele Friedrich, Birte Holtfreter   +8 more
wiley   +1 more source

CT, US and MRI of xanthine urinary stones: in-vitro and in-vivo analyses [PDF]

, 2020
Stephanie Shamir, Qi Peng, Alan H. Schoenfeld, Beth A. Drzewiecki, Mark C. Liszewski   +4 more
openalex   +1 more source