Results 11 to 20 of about 44,980 (368)
Diagnosing Parkinson’s disease and monitoring its progression: Biomarkers from combined GC-TOF MS and LC-MS/MS untargeted metabolomics [PDF]
HeliyonParkinson's disease (PD) is a prevalent neurodegenerative disorder with a poorly understood etiology. An accurate diagnosis of idiopathic PD remains challenging as misdiagnosis is common in routine clinical practice.
Lina A. Dahabiyeh +4 more
doaj +2 more sources
Oral xanthines as maintenance treatment for asthma in children
The Cochrane Library, 2006 BACKGROUND Xanthines have been used in the treatment of asthma as a bronchodilator, though they may also have anti-inflammatory effects. The current role of xanthines in the long-term treatment of childhood asthma needs to be reassessed.
Francine M Ducharme
exaly +2 more sources
Mice, men, mustard and methylated xanthines: the potential role of caffeine and related drugs in the sensitization of human tumours to alkylating agents. [PDF]
British Journal of Cancer, 1981 The relationships between DNA damage from UV radiation, alkylating drugs and the methylated xanthines (MX) have been studied in normal and malignant rodent and human cells.
J. Byfield +5 more
semanticscholar +5 more sources
The specificity of xanthine oxidase [PDF]
Biochemical Journal, 1938 Vernon Booth
openalex +4 more sources
Structure of the Adenosine A2A Receptor in Complex with ZM241385 and the Xanthines XAC and Caffeine
Structure, 2011 Nathan Robertson +2 more
exaly +2 more sources
Uric Acid or 1-Methyl Uric Acid in the Urinary Bladder Increases Serum Glucose, Insulin, True Triglyceride, and Total Cholesterol Levels in Wistar Rats [PDF]
The Scientific World Journal, 2003 In animals deprived of food for a long period, a drop in the fat mass below 5% of the total body mass results in an increase in blood glucocorticoids and uric acid levels, followed by foraging activity.
T. Balasubramanian
doaj +3 more sources
Molecules, 2021 Antimicrobial resistance is a major healthcare threat globally. Xanthines, including caffeine and pentoxifylline, are attractive candidates for drug repurposing, given their well-established safety and pharmacological profiles.
Anna Woziwodzka +6 more
doaj +1 more source
eLife, 2021 Mutations in TP53 occur commonly in the majority of human tumors and confer aggressive tumor phenotypes, including metastasis and therapy resistance. CB002 and structural-analogs restore p53 signaling in tumors with mutant-p53 but we find that unlike ...
Liz Hernandez Borrero +8 more
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Pharmaceuticals, 2021 As life expectancy increases, dementia affects a growing number of people worldwide. Besides current treatments, phosphodiesterase 9 (PDE9) represents an alternative target for developing innovative small molecules to contrast neurodegeneration.
Giovanni Ribaudo +2 more
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Metals, 2022 Metals stability and corrosion resistance are very important factors that influence the possibility of their applications. In order to study and foresee the behavior of metals during various applications in all kinds of conditions and media, numerous ...
Marija B. Petrović Mihajlović +4 more
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