Results 191 to 200 of about 6,368 (267)

Distinguishing Isomeric Caffeine Metabolites through Protomers and Tautomers Using Cryogenic Gas-Phase Infrared Spectroscopy. [PDF]

Anal Chem
Geue N, Prabhu GRD, Renzi E, Walton-Doyle C, Meijer G, von Helden G, Pagel K.   +6 more
europepmc   +1 more source

Single oral administration of dronabinol increases ocular blood flow in patients with glaucoma

Acta Ophthalmologica, Volume 104, Issue 2, Page 225-232, March 2026.
Abstract Purpose Glaucoma is a leading cause of irreversible blindness globally, primarily driven by elevated intraocular pressure (IOP). Still, some patients progress despite significant IOP lowering, potentially due to impaired ocular blood flow. This study aimed to evaluate the effects of dronabinol, a synthetic tetrahydrocannabinol derivative, on ...
Theresa Lindner, Viktoria Pai, Patrick Janku, Nikolaus Hommer, Anton Hommer, Marihan Abensperg‐Traun, Liudmyla Petric, Leopold Schmetterer, Gerhard Garhöfer, Doreen Schmidl   +9 more
wiley   +1 more source

Untargeted Metabolomics and Chemometrics Elucidate Dynamic Plasma Profile Changes Induced by Cocoa Shell in Female Rats. [PDF]

Nutrients
Ramiro-Cortijo D, Rebollo-Hernanz M, Rodríguez-Rodríguez P, Ruvira S, Arribas SM, Martin-Cabrejas MA.   +5 more
europepmc   +1 more source

Insights Into Gut Barrier Dysfunction and Metabolic Alterations in Mycophenolate‐Induced Enteropathy

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Mycophenolic acid (MPA) is a widely used immunosuppressant whose use is often limited by gastrointestinal toxicity. Gut bacterial hydrolysis of liver‐derived MPA glucuronides increases local exposure to MPA, potentially impairing epithelial barrier function and cellular metabolism.
Clarisse Brossier, François‐Ludovic Sauvage, Christel Valencia‐Schmitt, Valérie Calco, Pascal Villa, Pierre Marquet, Roland Lawson   +6 more
wiley   +1 more source

Chromatographic Profiling of Artisanal Chocolates: Volatile Composition and Methylxanthines as Markers of Cocoa Content. [PDF]

J Food Sci
Altissimo J, Cardoso I, Araújo BQ, Pereira AR, Almeida JVM, Santos NAD, Costa VC, Carneiro Lima MTWD.   +7 more
europepmc   +1 more source

Quercetin Enhances Gastric Nitric Oxide Formation and Potentiates the Antihypertensive Effects of Oral Nitrite Administration

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 3, March 2026.
ABSTRACT Oral nitrite supplementation enhances nitric oxide (NO) bioavailability and lowers blood pressure. Quercetin may facilitate the reduction of nitrite to NO. However, the combined effects of nitrite and Quercetin on gastric NO formation and blood pressure have not been explored.
Mila Silva‐Cunha, Sandra O. Conde‐Tella, Macário A. Rebelo, Isadora L. M. Kemmer, Ana K. Lima‐Silva, Ediléia de S. P. Caetano, Jose E. Tanus‐Santos   +6 more
wiley   +1 more source

Comparative Evaluation and Profiling of Chemical Tools for the Nuclear Hormone Receptor Family 2. [PDF]

ACS Pharmacol Transl Sci
Lewandowski M, Busch R, Marschner JA, Merk D.   +3 more
europepmc   +1 more source

Elevated Salivary Theobromine and Long‐Term Improvement of Periodontal Health in Two Cohort Studies

Journal of Clinical Periodontology, Volume 53, Issue 3, Page 445-454, March 2026.
ABSTRACT Background Theobromine, a methylxanthine mainly found in chocolate, has been suggested to possess various health‐promoting properties. This study aimed to investigate the long‐term effect of salivary theobromine levels on periodontitis severity using 7‐ and 10‐year follow‐up data from the prospective Studies of Health in Pomerania (SHIP‐TREND ...
Thomas Kocher, Sebastian‐Edgar Baumeister, Henry Völzke, Matthias Nauck, Peter Meisel, Karsten Suhre, Uwe Völker, Nele Friedrich, Birte Holtfreter   +8 more
wiley   +1 more source

Protective Effects of Early Neonatal Methylxanthine Treatment on Cognitive and Language Outcomes in Premature Infants with and without High-Risk Perinatal Factors.

Dev Neurosci
McLeod RM, Rosenkrantz TS, Fitch RH.
europepmc   +1 more source

Evaluation of Oxidative Stress and Antioxidant Effects of Methylxanthines in Adult Zebrafish Exposed to Zinc Oxide Nanoparticles (ZnO-NPs). [PDF]

Medicina (Kaunas)
Pavel CD, Chiţescu CL, Dragostin OM, Dediu L, Aprodu I, Iacob AD, Vatcu R, Zamfir AS, Zamfir CL.   +8 more
europepmc   +1 more source