Results 51 to 60 of about 44,980 (368)
Effects of early aminophylline therapy on clinical outcomes in premature infants
Pediatrics and Neonatology, 2023 Background: Aminophylline use and the association between clinical outcomes and therapy timing have been less investigated. The objective of this study was to determine the efficacy of early aminophylline use (within the first two days of life) in ...
Yi-Ting Chu +6 more
doaj
Deep Supramolecular Language Processing for Co‐Crystal Prediction
Angewandte Chemie, EarlyView.DeepCocrystal is a deep learning model that predicts co‐crystal formation by learning supramolecular interactions from molecular string representations. It achieves high accuracy, estimates uncertainty, and offers interpretable insights into its predictions. Validated prospectively, DeepCocrystal discovered novel diflunisal co‐crystals and is available
Rebecca Birolo +5 more
wiley +2 more sources
The inflluence of emulsifiers on physical properties and release parameters of creams with caffeine
Current Issues in Pharmacy and Medical Sciences, 2015 Caffeine is well known alkaloid chemical compound belonging to the methyl-xanthines group. It is an active substance that is found in many cosmetic products, as it has a stimulating action on both the central nervous system and the metabolism ...
Dwornicka Dorota +6 more
doaj +1 more source
Scientific Reports, 2021 Kombucha is a beverage made by fermenting sugared tea using a symbiotic culture of bacteria belonging to the genus Acetobacter, Gluconobacter, and the yeasts of the genus Saccharomyces along with glucuronic acid, which has health-promoting properties ...
Aleksandra Ziemlewska +5 more
doaj +1 more source
Progress in the discovery of selective, high affinity A2B adenosine receptor antagonists as clinical candidates [PDF]
, 2008 The selective, high affinity A2B adenosine receptor (AdoR) antagonists that were synthesized by several research groups should aid in determining the role of the A2B AdoR in inflammatory diseases like asthma or rheumatoid arthritis (RA) and angiogenic ...
A Stefanchi +41 more
core +2 more sources
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source
Molecules, 2019 8-Arylethynylxanthine derivatives are potent, selective adenosine A2A receptor antagonists, which represent (potential) therapeutics for Parkinson’s disease, Alzheimer’s dementia, and the immunotherapy of cancer.
Daniel Marx +3 more
doaj +1 more source
Dihydrofolate Reductase Inhibitors: The Pharmacophore as a Guide for Co-Crystal Screening
Molecules, 2021 In this work, co-crystal screening was carried out for two important dihydrofolate reductase (DHFR) inhibitors, trimethoprim (TMP) and pyrimethamine (PMA), and for 2,4-diaminopyrimidine (DAP), which is the pharmacophore of these active pharmaceutical ...
João A. Baptista +7 more
doaj +1 more source
Word Records From Webster\u27s Third [PDF]
, 1990 This article contains a list of words with interesting logological properties from Merriam-Webster\u27s Third New International Dictionary (1961) and 12000 Words: A Supplement to Webster\u27s Third (1986).
Cole, Chris
core +1 more source
Advanced Sensor Research, EarlyView.Magnetic particle spectroscopy and imaging represent promising tools, particularly when combined with manganese‐ferrite nanoparticles as versatile theranostic agents. Adjusting the manganese content allows for simultaneous multi‐color tracer detection and reactive oxygen species sensing via magnetic particle spectroscopy and imaging, creating new ...
Fabian H. L. Starsich +10 more
wiley +1 more source