Results 61 to 70 of about 4,620 (190)
Depot-specific inflammation with decreased expression of ATM2 in white adipose tissues induced by high-margarine/lard intake. [PDF]
A high-fat diet has been recognized as an important risk factor of obesity, with variable impacts of different fatty acid compositions on the physiological process. To understand the effects of a high-margarine/lard diet, which is a major source of trans
Nannan Wang +8 more
doaj +1 more source
Struktur-Funktionsanalyse des Chemokins XCL1
Einleitung Chemokine vermitteln die Interaktion von Immunzellen. Das Chemokin XCL1 wird von aktivierten CD8+ T-Zellen und NK-Zellen sezerniert und besitzt die für Chemokine typische Tertiärstruktur, bestehend aus einem N-Terminus, einem antiparallelen β-Faltblatt, einer α Helix und einem freien C-Terminus von etwa 20 Aminosäuren.
openaire +2 more sources
BackgroundAlopecia areata (AA) is a disease featured by recurrent, non-scarring hair loss with a variety of clinical manifestations. The outcome of AA patients varies greatly.
Yuanquan Zheng +4 more
doaj +1 more source
Dendritic cells (DC) play a crucial role in generating and maintaining antiviral immunity. While DC are implicated in the antiviral defense by inducing T cell responses, they can also become infected by Cytomegalovirus (CMV).
Julia Cecilia Madela-Mönchinger +9 more
doaj +1 more source
Aberrant Tissue Positioning of Metallophilic Macrophages in the Thymus of XCL1‐Deficient Mice [PDF]
ABSTRACTMetallophilic macrophages hold a strategic position within the thymic tissue and play a considerable function in thymic physiology. The development and positioning of these cells within thymic tissue are regulated by complex molecular mechanisms involving different cytokine/chemokine axes.
Novica M. Milićević +6 more
openaire +2 more sources
Bordetella spp. block eosinophil recruitment to suppress the generation of early mucosal protection
Summary: Bordetella spp. are respiratory pathogens equipped with immune evasion mechanisms. We previously characterized a Bordetella bronchiseptica mutant (RB50ΔbtrS) that fails to suppress host responses, leading to rapid clearance and long-lasting ...
Nicholas J. First +9 more
doaj +1 more source
Enhanced ion conduction by enforcing structural disorder in Li-deficient argyrodites Li6−xPS5−xCl1+x
Solid electrolytes with high ionic conductivity and good stability are advantageous over the current liquid electrolytes in rechargeable Li-ion batteries.
Xuyong Feng +7 more
semanticscholar +1 more source
Summary: Transposable elements (TEs) can provide ectopic promoters to drive the expression of oncogenes in cancer, a mechanism known as onco-exaptation.
Ziwei Wang +9 more
doaj +1 more source
Single‐cell analyses reveal suppressive tumor microenvironment of human colorectal cancer
Profiling heterologous cell types within tumors is essential to decipher tumor microenvironment that shapes tumor progress and determines the outcome of therapeutic response.
Yan Mei +17 more
doaj +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source

