Results 41 to 50 of about 6,545 (188)

Aberrant Tissue Positioning of Metallophilic Macrophages in the Thymus of XCL1‐Deficient Mice [PDF]

The Anatomical Record, 2014
ABSTRACTMetallophilic macrophages hold a strategic position within the thymic tissue and play a considerable function in thymic physiology. The development and positioning of these cells within thymic tissue are regulated by complex molecular mechanisms involving different cytokine/chemokine axes.
Novica M. Milićević, Ivana M. Lalić, Sanja Z. Despotović, Darko N. Ćirić, Jűrgen Westermann, Rene De Waal Malefyt, Živana Milićević   +6 more
openaire   +2 more sources

Cytokines Elevated in HIV Elite Controllers Reduce HIV Replication In Vitro and Modulate HIV Restriction Factor Expression [PDF]

, 2017
A subset of HIV-infected individuals termed elite controllers (ECs) maintain CD4+ T cell counts and control viral replication in the absence of antiretroviral therapy (ART).
Abdel-Mohsen, M, Anastos, K, Crystal, H, Deeks, SG, Deng, X, Gange, SJ, Gibb, SL, Golub, ET, Greenblatt, RM, Heitman, JW, Inglis, HC, Jacobs, ES, Kaidarova, Z, Keating, SM, Landay, AL, Martin, JN, Norris, PJ, Pillai, SK, Villacres, MC, Wu, S, Young, M, Zhang, J   +21 more
core   +1 more source

Expression and Function of the C-Class Chemokine Lymphotactin (XCL1) in Wegener’s Granulomatosis [PDF]

The Journal of Rheumatology, 2009
Objective.In Wegener’s granulomatosis (WG), vasculitic lesions are characterized by prominent infiltration of polymorphonuclear neutrophils (PMN) and T cells, but underlying pathogenic mechanisms remain to be defined. We analyzed the expression and functional role of the C-class chemokine lymphotactin, XCL1, in WG.Methods.Sera and peripheral blood ...
Blaschke, Sabine, Brandt, Philip, Wessels, Johannes Theodor, Mueller, Georg Anton   +3 more
openaire   +3 more sources

Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells. [PDF]

, 2016
BackgroundOur previous studies showed that the non-psychoactive cannabinoid, cannabidiol (CBD), ameliorates the clinical symptoms in mouse myelin oligodendrocyte glycoprotein (MOG)35-55-induced experimental autoimmune encephalomyelitis model of multiple ...
Coppola, Giovanni, Gao, Fuying, Juknat, Ana, Kaushansky, Nathali, Kozela, Ewa, Vogel, Zvi   +5 more
core   +2 more sources

Do Quarks Obey D-Brane Dynamics? [PDF]

, 1999
The potential between two D0-branes at rest is calculated to be a linear. Also the potential between two fast decaying D0-branes is found in agreement with phenomenological heavy-quark potentials.Comment: 7 pages, no figures ...
A. H Fatollahi, Abbot L. F., Banks T., Bialas A., Close F. E., Collins P. D. B., Diamantini M. C., Dijkgraaf R., Fayyazuddin A., Gomes C., Kiritsis E., Peschanski R., Polchinski J., Polchinski J., Polyakov A. M., Schwartz J. H., Sen A., Taylor W., Vafa C. V.   +18 more
core   +5 more sources

Shared and distinct transcriptional programs underlie the hybrid nature of iNKT cells [PDF]

, 2013
Invariant natural killer T cells (iNKT cells) are innate-like T lymphocytes that act as critical regulators of the immune response. To better characterize this population, we profiled gene expression in iNKT cells during ontogeny and in peripheral ...
A Bendelac, A Bendelac, A Reschner, AK Savage, AM Fahrer, B Johnston, BM Sullivan, BN Weber, C Grégoire, C Kuylenstierna, C Paget, D Kovalovsky, DI Godfrey, DI Godfrey, DM Andrews, E Vivier, Gerald F Watts, H Sun, H Watarai, HD Marshall, J Shires, JE Gumperz, JL Matsuda, JL Matsuda, JL Matsuda, JM Coquet, Joonsoo Kang, K Inagaki-Ohara, K Miyazaki, L Gattinoni, L Gattinoni, LE Gordy, LL Lanier, M Brigl, M Brigl, M Brigl, M Maeda, M Salio, MA Cooper, Manfred Brigl, Michael B Brenner, MJ Townsend, MS Vincent, Nadia R Cohen, NC Fernandez, NR Cohen, NY Crowe, P Kastner, Patrick J Brennan, PD Thomas, PJ Brennan, RL O'Brien, S Honma, S Yu, T Kawamura, T Ota, T Walzer, T Willinger, Tal Shay, TSP Heng, V Cerundolo, W Huang da, X Yue, Y Makino   +63 more
core   +5 more sources

A novel predictive model for the recurrence of pediatric alopecia areata by bioinformatics analysis and a single-center prospective study

Frontiers in Medicine, 2023
BackgroundAlopecia areata (AA) is a disease featured by recurrent, non-scarring hair loss with a variety of clinical manifestations. The outcome of AA patients varies greatly.
Yuanquan Zheng, Yingli Nie, Jingjing Lu, Hong Yi, Guili Fu   +4 more
doaj   +1 more source

A team effort: natural killer cells on the first leg of the tumor immunity relay race [PDF]

, 2018
Recent work by Böttcher and colleagues defines a new role for Natural Killer cells in the anti-tumor immune response, arriving early into the tumor microenvironment before passing the baton to DC1 dendritic cells.
Duong, Ellen, Fessenden, Timothy B, Spranger-Zimmermann, Stefani   +2 more
core   +1 more source

Rat cytomegalovirus efficiently replicates in dendritic cells and induces changes in their transcriptional profile

Frontiers in Immunology, 2023
Dendritic cells (DC) play a crucial role in generating and maintaining antiviral immunity. While DC are implicated in the antiviral defense by inducing T cell responses, they can also become infected by Cytomegalovirus (CMV).
Julia Cecilia Madela-Mönchinger, Silver Anthony Wolf, Emanuel Wyler, Agnieszka Bauer, Marius Mischke, Lars Möller, Vanda Juranić Lisnić, Markus Landthaler, Anna Malyshkina, Sebastian Voigt   +9 more
doaj   +1 more source

Altered expression of autoimmune regulator in infant down syndrome thymus, a possible contributor to an autoimmune phenotype. [PDF]

, 2014
To access publisher's full text version of this article click on the hyperlink at the bottom of the pageDown syndrome (DS), caused by trisomy of chromosome 21, is associated with immunological dysfunctions such as increased frequency of infections and ...
Annerén, Göran, Berglund, Martin, Ekwall, Olov, Gudmundsdottir, Judith, Gustafsson, Jan, Kämpe, Olle, Lindgren, Susanne, Lundberg, Vanja, Sandström, Kerstin, Skogberg, Gabriel, Sunnegårdh, Jan, Telemo, Esbjörn, van der Post, Sjoerd   +12 more
core   +1 more source