Results 51 to 60 of about 4,838 (170)

Plastid Engineering for Photosynthesis‐Driven Synthesis of Hyaluronic Acid in Tobacco

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2541-2558, April 2026.
ABSTRACT Hyaluronic acid (HA) is a glycosaminoglycan composed of alternating units of N‐acetylglucosamine and glucuronic acid. High moisture retention, viscoelasticity and biocompatibility are unique features that make HA polymers attractive compounds for medical applications and aesthetic purposes.
Amanda Lopes, Omar Sandoval‐Ibáñez, Stéphanie Arrivault, David Rolo, F. Vanessa Loiacono, Alexander Erban, Daniel Karcher, Stephan Obst, Stephanie Ruf, Joachim Kopka, Ralph Bock   +10 more
wiley   +1 more source

Efficient anaerobic consumption of D-xylose by E. coli BL21(DE3) via xylR adaptive mutation

BMC Microbiology, 2021
Background Microorganisms can prioritize the uptake of different sugars depending on their metabolic needs and preferences. When both D-glucose and D-xylose are present in growth media, E.
Jung Min Heo, Hyun Ju Kim, Sang Jun Lee
doaj   +1 more source

Convergent Evolution and De Novo Reconstitution of Apiin Biosynthesis

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2562-2575, April 2026.
ABSTRACT Apiin, an active flavonoid apioside, occurs in phylogenetically distant plants, such as parsley and chilli pepper (Capsicum annuum L.). Its sporadic distribution suggests the existence of convergent apiin biosynthesis; however, the molecular mechanisms underlying this convergence remain unclear.
Zhen Xu, Zheng‐Shuang Zhu, Hai‐Zhu Jia, Jian‐Qiang Kong   +3 more
wiley   +1 more source

Development of Efficient Xylose Fermentation in Saccharomyces cerevisiae: Xylose Isomerase as a Key Component

, 2007
Metabolic engineering of Saccharomyces cerevisiae for ethanol production from D-xylose, an abundant sugar in plant biomass hydrolysates, has been pursued vigorously for the past 15 years. Whereas wild-type S. cerevisiae cannot ferment D-xylose, the keto-isomer D-xylulose can be metabolised slowly.
Van Maris, A.J.A. (author), Winkler, A.A. (author), Kuyper, M. (author), De Laat, W.T. (author), Van Dijken, J.P. (author), Pronk, J.T. (author)   +5 more
openaire   +4 more sources

Systematic Metabolic Engineering and Model‐Guided Optimization for High‐Level Production of L‐Theanine from Xylose in Escherichia coli

Advanced Science, Volume 13, Issue 17, 23 March 2026.
This study is pioneering in constructing the shortest known synthetic pathway for L‐theanine production from xylose within E coli. Through comprehensive metabolic engineering strategies, our engineered strain achieved the highest reported L‐theanine titer from xylose, with a titer of 95.42 g/L, and a yield of 0.55 g/g.
Haolin Han, Boyuan Xue, Guangqi Shan, Meng Meng, Shaojie Wang, Haijia Su   +5 more
wiley   +1 more source

Directed Evolution of Xylose Isomerase for Improved Xylose Catabolism and Fermentation in the Yeast Saccharomyces cerevisiae [PDF]

Applied and Environmental Microbiology, 2012
ABSTRACT The heterologous expression of a highly functional xylose isomerase pathway in Saccharomyces cerevisiae would have significant advantages for ethanol yield, since the pathway bypasses cofactor requirements found in the traditionally used oxidoreductase pathways. However, nearly all reported xylose
Lee, Sun-Mi, Jellison, Taylor, Alper, Hal S.   +2 more
openaire   +3 more sources

Neutron Crystallography Study of Host–Pathogen Recognition Enhanced by Hydrogen/Deuterium Exchange on Carbohydrates

ChemistryEurope, Volume 4, Issue 3, March 2026.
Neutron macromolecular crystallography enabled by deuteration of biomolecules reveals how the opportunistic pathogen Pseudomonas aeruginosa utilizes calcium‐dependent lectin for binding to human sugars. Neutron diffraction on the complex highlights hydrogen bond network, protonation of amino acids and role of calcium ion.
Theodore Arnaud, Chloé Tatol, Juliette M. Devos, Lukas Gajdos, Sébastien Vidal, Marek Korsak, Annabelle Varrot, Michaela Wimmerova, Sophie Feuillastre, Matthew P. Blakeley, Anne Imberty   +10 more
wiley   +1 more source

Safety evaluation of the food enzyme glucose isomerase from Streptomyces murinus (strain NZYM‐GA)

EFSA Journal, 2019
The food enzyme is a glucose isomerase (d‐xylose aldose‐ketose‐isomerase; EC 5.3.1.5) produced with a non‐genetically modified Streptomyces murinus strain NZYM‐GA by Novozymes A/S.
EFSA Panel on Food Contact Materials, Enzymes and Processing Aids (CEP), Vittorio Silano, José Manuel Barat Baviera, Claudia Bolognesi, Beat Johannes Brüschweiler, Pier Sandro Cocconcelli, Riccardo Crebelli, David Michael Gott, Konrad Grob, Evgenia Lampi, Alicja Mortensen, Gilles Rivière, Inger‐Lise Steffensen, Christina Tlustos, Henk Van Loveren, Laurence Vernis, Holger Zorn, Boet Glandorf, Lieve Herman, Francesca Marcon, André Penninks, Andrew Smith, Jaime Aguilera, Natalia Kovalkovicova, Yi Liu, Joaquim Maia, Karl‐Heinz Engel, Andrew Chesson   +27 more
doaj   +1 more source

Comparison of Three Xylose Pathways in Pseudomonas putida KT2440 for the Synthesis of Valuable Products

Frontiers in Bioengineering and Biotechnology, 2020
Pseudomonas putida KT2440 is a well-established chassis in industrial biotechnology. To increase the substrate spectrum, we implemented three alternative xylose utilization pathways, namely the Isomerase, Weimberg, and Dahms pathways.
Isabel Bator, Andreas Wittgens, Andreas Wittgens, Andreas Wittgens, Frank Rosenau, Frank Rosenau, Frank Rosenau, Till Tiso, Lars M. Blank   +8 more
doaj   +1 more source

The Weimberg pathway: an alternative for Myceliophthora thermophila to utilize d-xylose

Biotechnology for Biofuels and Bioproducts, 2023
Background With d-xylose being the second most abundant sugar in nature, its conversion into products could significantly improve biomass-based process economy. There are two well-studied phosphorylative pathways for d-xylose metabolism. One is isomerase
Defei Liu, Yongli Zhang, Jingen Li, Wenliang Sun, Yonghong Yao, Chaoguang Tian   +5 more
doaj   +1 more source