Results 41 to 50 of about 7,321 (167)

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Increased Ethanol Productivity in Xylose-Utilizing Saccharomyces cerevisiae via a Randomly Mutagenized Xylose Reductase [PDF]

Applied and Environmental Microbiology, 2010
ABSTRACT Baker's yeast ( Saccharomyces cerevisiae ) has been genetically engineered to ferment the pentose sugar xylose present in lignocellulose biomass. One of the reactions controlling the rate of xylose utilization is catalyzed by xylose reductase (XR).
David, Runquist, Bärbel, Hahn-Hägerdal, Maurizio, Bettiga   +2 more
openaire   +2 more sources

Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae. [PDF]

PLoS Genetics, 2016
The inability of native Saccharomyces cerevisiae to convert xylose from plant biomass into biofuels remains a major challenge for the production of renewable bioenergy.
Trey K Sato, Mary Tremaine, Lucas S Parreiras, Alexander S Hebert, Kevin S Myers, Alan J Higbee, Maria Sardi, Sean J McIlwain, Irene M Ong, Rebecca J Breuer, Ragothaman Avanasi Narasimhan, Mick A McGee, Quinn Dickinson, Alex La Reau, Dan Xie, Mingyuan Tian, Jennifer L Reed, Yaoping Zhang, Joshua J Coon, Chris Todd Hittinger, Audrey P Gasch, Robert Landick   +21 more
doaj   +1 more source

DNA‐Enzyme Hybrid Nanostructures: Functional Materials to Modulate Enzymatic Activity

Small, Volume 22, Issue 43, 3 August 2026.
DNA–enzyme hybrid nanostructures enable precise spatial and stoichiometric control over enzyme organization, offering a powerful platform to modulate catalytic activity. This review critically evaluates key mechanistic hypotheses, including proximity effects, microenvironment changes, confinement, and stabilization, as well as highlighting ...
Manar Elnaggar, Amelie Heuer‐Jungemann
wiley   +1 more source

Beneath the Bark: Molecular Determinants of Adaptation and Infection in Bacterial Pathogens of Woody Hosts

Molecular Plant Pathology, Volume 27, Issue 8, August 2026.
Bacterial pathogens colonise woody hosts by integrating metabolic adaptation, effector‐mediated immune suppression, cell wall remodelling and EPS‐ and toxin‐supported persistence. ABSTRACT Bacterial pathogens of woody plants represent a pervasive yet underexplored threat to global agriculture and forestry, causing devastating diseases in fruit trees ...
Antonio Arroyo‐Mateo, Jesús Murillo, Luis Rodríguez‐Moreno, Cayo Ramos   +3 more
wiley   +1 more source

Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae

Biotechnology for Biofuels, 2009
Background Xylose reductase (XR) and xylitol dehydrogenase (XDH) from Pichia stipitis are the two enzymes most commonly used in recombinant Saccharomyces cerevisiae strains engineered for xylose utilization.
Hahn-Hägerdal Bärbel, Bengtsson Oskar, Gorwa-Grauslund Marie F   +2 more
doaj   +1 more source

Conserved symbiosis‐associated genes in the cycad Encephalartos natalensis suggest co‐option for cyanobacterial symbiosis

New Phytologist, Volume 251, Issue 4, Page 2168-2185, August 2026.
The heterocyst‐rich Encephalartos natalensis cyanobacterial zone in coralloid root suggests co‐option of conserved symbiosis‐associated genes. This figure was created in BioRender (BioRender.com/https://BioRender.com/n3qveqc). Summary Plant‐cyanobacterial symbioses have evolved independently at least four times across land plants, yet their underlying ...
Cassandra Schoeman, Danielle Roodt, Amy Mc Menamin, Oliver Bezuidt, Choaro Dithugoe, Desré Pinard, Eshchar Mizrachi   +6 more
wiley   +1 more source

Calcium and Nitrogen Availability Controls Root Exudation in Hydroponically Cultured Barley

Plant, Cell &Environment, Volume 49, Issue 8, Page 5210-5227, August 2026.
ABSTRACT Root exudation is a key component of plant‐rhizosphere interactome. It is increasingly evident that root exudates influence rhizospheric microbial communities and in turn can benefit plants through improved resource allocation. However, how suboptimal nutrient availability relates to control of root exudation is poorly understood.
Ibadete Denjali, Vijay Kumar, Joana Janzen, Marcus Persicke, László Cselényi, Refat Abdel‐Basset, Karl‐Josef Dietz   +6 more
wiley   +1 more source

Metabolic Engineering of Escherichia coli for Xylitol Production

Fermentation
Xylitol is a sugar–alcohol compound with broad applications in fields such as the food, dental, and pharmaceutical sectors. Although xylitol biosynthesis has gained attention, the current strategy for industrial xylitol production majorly relies on the ...
Jiapeng Li, Lei Zhang, Changzheng Li, Zhaoqing He, Xiongying Yan, Shihui Yang   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, Volume 600, Issue 14, Page 2063-2076, July 2026.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source