Characterization of a xylitol dehydrogenase from Aspergillus flavus and its application in l-xylulose production [PDF]
An NAD+-dependent xylitol dehydrogenase from A. flavus (AfXDH) was cloned and successfully expressed in Escherichia coli. AfXDH gene sequence revealed an open reading frame of 1,110 bp, encoding a polypeptide of 369 amino acids with a calculated ...
Anurag Kumar +7 more
doaj +2 more sources
Acquisition of a gene cluster in Clostridioides difficile PCR ribotype 023 strains enables xylitol utilization [PDF]
Hundreds of ribotypes of the gastrointestinal pathogen Clostridioides difficile have emerged over the last three decades, yet the factors driving their emergence are poorly understood.
Katherine J. Wozniak +6 more
doaj +2 more sources
Improving xylitol production by semi-rational engineering of xylitol dehydrogenase and optimizing cofactor regeneration in Gluconobacter oxydans [PDF]
Background Xylitol, a widely used sugar substitute in food and medicine, can be produced through microbial bioconversion using glucose as the primary substrate. In this process, a critical factor limiting xylitol production is the relatively low activity
Jun-Hao Su +4 more
doaj +2 more sources
Xylose fermentation efficiency of industrial Saccharomyces cerevisiae yeast with separate or combined xylose reductase/xylitol dehydrogenase and xylose isomerase pathways [PDF]
Background Xylose isomerase (XI) and xylose reductase/xylitol dehydrogenase (XR/XDH) pathways have been extensively used to confer xylose assimilation capacity to Saccharomyces cerevisiae and tackle one of the major bottlenecks in the attainment of ...
Joana T. Cunha +4 more
doaj +2 more sources
Metabolic engineering for sustainable xylitol production from diverse carbon sources in Pichia pastoris [PDF]
Xylitol, known for its health benefits, is a valuable compound in the food and pharmaceutical industries. However, conventional chemical production methods are often unsustainable for large-scale applications, prompting the need for alternative ...
Xiaocong Lu +8 more
doaj +2 more sources
Heterologous expression of Spathaspora passalidarum xylose reductase and xylitol dehydrogenase genes improved xylose fermentation ability of Aureobasidium pullulans [PDF]
Background Aureobasidium pullulans is a yeast-like fungus that can ferment xylose to generate high-value-added products, such as pullulan, heavy oil, and melanin.
Jian Guo +4 more
doaj +2 more sources
Identification of NAD-Dependent Xylitol Dehydrogenase from Gluconobacter oxydans WSH-003 [PDF]
Li Liu +4 more
doaj +2 more sources
Data for rapid ethanol production at elevated temperatures by engineered thermotolerant Kluyveromyces marxianus via the NADP(H)-preferring xylose reductase–xylitol dehydrogenase pathway [PDF]
A thermo-tolerant NADP(H)-preferring xylose pathway was constructed in Kluyveromyces marxianus for ethanol production with xylose at elevated temperatures (Zhang et al., 2015 [25]).
Biao Zhang +5 more
doaj +2 more sources
Background Commercial xylose purification produces xylose mother liquor (XML) as a major byproduct, which has become an inexpensive and abundant carbon source.
Lihua Zhang +5 more
doaj +1 more source
Background Xylitol has a wide range of applications in the pharmaceuticals, cosmetic, food and beverage industry. Microbial xylitol production reduces the risk of contamination and is considered as environment friendly and sustainable compared to the ...
Anup Kumar Singh +6 more
doaj +1 more source

