Results 101 to 110 of about 25,112 (256)
Engineering yeast alcohol dehydrogenase. Replacing Trp54 by Leu broadens substrate specificity
Analysis of a crystal structure of alcohol dehydrogenase (Adh) from horse liver suggests that Trp54 in the homologous yeast alcohol dehydrogenase prevents the yeast enzyme from efficiently catalysing the oxidation of long-chain primary alcohols with ...
Weinhold, Elmar G., Benner, Steven A.
core
S.84-92A transcriptome analysis was performed of Saccharomyces cerevisiae undergoing isoamyl alcohol-induced filament formation. In the crucial first 5 h of this process, only four mRNA species displayed strong and statistically significant increases in ...
Brown, A.J.P. +6 more
core +1 more source
A personal 360° view of applications of ‘biomimetic’ molecular recognition
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley +1 more source
Enantiocomplementary Bioreduction of 1-(Arylsulfanyl)propan-2-ones
This study explored the enantiocomplementary bioreduction of substituted 1-(arylsulfanyl)propan-2-ones in batch mode using four wild-type yeast strains and two different recombinant alcohol dehydrogenases from Lactobacillus kefir and Rhodococcus ...
Emese Sándor +3 more
doaj +1 more source
Background 2,3-Butanediol (2,3-BDO) is a valuable chemical for industrial applications. Bacteria can produce 2,3-BDO with a high productivity, though most of their classification as pathogens makes them undesirable for the industrial-scale production ...
Ye-Gi Lee, Jin-Ho Seo
doaj +1 more source
Specific base catalysis by yeast alcohol dehydrogenase I with substitutions of histidine-48 by glutamate or serine residues in the proton relay system. [PDF]
Plapp BV +4 more
europepmc +1 more source
Description of the rate‐limiting hydrogen tunneling mechanism for plant 9‐ and 13‐lipoxygenases
Abstract Soybean lipoxygenase (GmLOX1), a plant 13‐LOX, has long been considered a model protein for non‐trivial, quantum hydrogen tunneling in enzyme catalysis. Hydrogen tunneling mechanisms have also been confirmed for LOXs across mammalian, fungal, and bacterial kingdoms.
Alex Kockler +7 more
wiley +1 more source
The Thr45Gly substitution in yeast alcohol dehydrogenase substantially decreases catalysis, alters pH dependencies, and disrupts the proton relay system. [PDF]
Pal S, Plapp BV.
europepmc +1 more source
RNA interference (RNAi) technologies, host‐induced gene silencing (HIGS) and spray‐induced gene silencing (SIGS), potentially offer sustainable crop protection. However, efficacy, costs, regulatory clarity, and socio‐environmental impacts require further evaluation for broader use.
Elisabetta Sergi +12 more
wiley +1 more source
Sirtuins as regulators of the yeast metabolic network
There is growing evidence that the metabolic network is an integral regulator of cellularphysiology. Dynamic changes in metabolite concentrations, metabolic flux, or networktopology act as reporters of biological or environmental signals, and are ...
Markus eRalser +3 more
doaj +1 more source

